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Study provides a new target for therapeutic intervention in Parkinson's disease

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson's disease.

14 Nov 2021

Study improves understanding of the link between obesity and gum disease

Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.

12 Nov 2021

Study: Patients meeting a particular criteria need invasive procedures to treat chronic neck pain

The use of radiofrequency ablation--targeted heat from an electrical current to ease nerve pain--may be helpful for treating chronic neck pain, but only in patients meeting particular criteria, conclude evidence-based consensus guidelines, published online in the journal Regional Anesthesia & Pain Medicine.

12 Nov 2021

Potential therapeutic targets of hydrogen for treatment of the COVID-19

A recent article provided a review of a study led by academician Zhong Nanshan, in China, on COVID-19 treatment by inhalation of a mixed gas composed of hydrogen and oxygen.

12 Nov 2021

COVID-19 vaccination humoral immune response in individuals with diabetes

A new study investigated the humoral immune response and side effects related to COVID-19 vaccines in individuals with type 1 diabetes and type 2 diabetes.

12 Nov 2021

Will the future of global health rely upon addressing air pollution?

We speak to Dr. Philip Landrigan about his latest research into air pollution and how African countries are in a prime position to take action against it.

12 Nov 2021

Bariatric surgery lowers risk of liver disease, heart complications in patients with fatty liver disease

A Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric weight loss surgery significantly lowered their future risk of liver disease complications and serious cardiovascular disease compared with patients who did not have surgery.

11 Nov 2021

Combination treatment improves overall survival for melanoma patients with brain metastases

Combination treatment with immune checkpoint inhibitors nivolumab and ipilimumab demonstrates overall survival for patients with melanoma that has spread to the brain, according to Phase II study results published today in The Lancet Oncology by researchers from The University of Texas MD Anderson Cancer Center.

11 Nov 2021

Low amount of caffeine intake during pregnancy may help reduce gestational diabetes risk

Good news for pregnant coffee lovers: Consuming a low amount of caffeine during pregnancy could help to reduce gestational diabetes risk, according to researchers in the Perelman School of Medicine at the University of Pennsylvania and the National Institutes of Health. The findings were published Monday in JAMA Network Open.

11 Nov 2021

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Phage-like particle system provides a platform for quick and easy vaccine generation

In this study, researchers report on the development of a monovalent lambda PLP-based vaccine against SARS-CoV-2 or MERS-Cov through decoration with the spike RBD proteins from either virus.

11 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

Researchers uncover new genetic link to non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases. It is often associated with obesity and diabetes and is considered a manifestation of metabolic syndrome.

10 Nov 2021

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

Older women with sarcopenia less likely to experience hot flashes

The loss of muscle mass is a natural part of aging. Older women with sarcopenia (age-related loss of muscle mass and function) are at an increased risk of reduced mobility, diminished quality of life, heart disease, and fall-related injuries.

10 Nov 2021

Western boom cities see spike in harmful ozone

The reduction of harmful ground-level ozone across most of the U.S. over the past several decades has been an air pollution success story.

10 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Rare diseases are usually caused by a single genetic defect. Nevertheless, the search for the cause and the assessment of the effects is highly complex and difficult.

9 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

Inflammation News and Research

Study provides a new target for therapeutic intervention in Parkinson's disease

Study improves understanding of the link between obesity and gum disease

Study: Patients meeting a particular criteria need invasive procedures to treat chronic neck pain

Potential therapeutic targets of hydrogen for treatment of the COVID-19

COVID-19 vaccination humoral immune response in individuals with diabetes

Will the future of global health rely upon addressing air pollution?

Bariatric surgery lowers risk of liver disease, heart complications in patients with fatty liver disease

Combination treatment improves overall survival for melanoma patients with brain metastases

Low amount of caffeine intake during pregnancy may help reduce gestational diabetes risk

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

Phage-like particle system provides a platform for quick and easy vaccine generation

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

Researchers uncover new genetic link to non-alcoholic steatohepatitis

The autoantibody profile in COVID-19 patients with MIS-C

Older women with sarcopenia less likely to experience hot flashes

Western boom cities see spike in harmful ozone

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

COVID-19 and loss of sense of smell

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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