Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scientists study how cancer spreads through the body

Because of results seen in flat lab dishes, biologists have believed that cancers cells move through the body in a slow, aimless fashion, resembling an intoxicated person who cannot walk three steps in a straight line.

12 Mar 2014

Parkinson disease patients with higher CSF experience faster cognitive decline

Counterintuitive Findings Offer New Insights into Parkinson Disease Pathology, According to New Research Published in The American Journal of Pathology

12 Mar 2014

Oncologists use mathematical model to develop treatment plans for cancer patients

Physics applies to everything. So when Vittorio Cristini, PhD, started researching cancer, he applied physics. The result he got was a set of mathematical equations that describe, for each person, how many of their tumor cells a cancer treatment could kill.

12 Mar 2014

Decision-making accuracy can be improved by postponing onset of decision

Columbia University Medical Center (CUMC) researchers have found that decision-making accuracy can be improved by postponing the onset of a decision by a mere fraction of a second.

10 Mar 2014

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Based on the pioneering work of Dr. Claire Lugassy and Dr. Raymond Barnhill at UCLA's Jonsson Comprehensive Cancer Center, a new study provides additional support for a process by which melanoma cells, a deadly form of skin cancer, can spread throughout the body by creeping like tiny spiders along the outside of blood vessels without ever entering the blood stream, and that this process is exacerbated by exposure to ultraviolet (UV) light.

10 Mar 2014

Tissue analysis near tumors holds promise for earlier detection, new treatments

Seemingly healthy cells may in fact hide clues that lung cancer will later develop, according to a study led by researchers at The University of Texas MD Anderson Cancer Center The research is published online in the Journal of the National Cancer Institute.

9 Mar 2014

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Three longtime allies have joined forces to create the new Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence.

7 Mar 2014

Treating long wait-times dictate long-term success of spinal cord stimulation therapy

Success rates soared to 75% for patients who waited less than 2 years for a spinal cord stimulator (SCS) implant, compared with 15% for patients whose implants happened 20 years after the onset of pain, according to a retrospective analysis.

7 Mar 2014

Scientists identify important step toward shutting down growth of prostate cancer cells

Scientists at UT Southwestern Medical Center have identified an important step toward potentially shutting down the growth of prostate cancer cells.

7 Mar 2014

New findings shed light on how gene mutation causes motor neurone disease

Researchers have discovered a mechanism that may explain how a recently discovered mutation causes two devastating neurological diseases.

6 Mar 2014

New drug is effective against superbug MRSA

"I routinely call hospitals and request their yearly antibiotic susceptibility testing data," said Washington University in St. Louis' Timothy Wencewicz. "The log might say, for example, that they've treated hundreds of patients for Acinetobacter baumanni, a bacterium brought into U.S. hospitals by soldiers wounded in the Iraq war, with 30 different antibiotics.

6 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Agenus Inc., a biopharmaceutical company developing a portfolio of immuno-oncology candidates, including checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants, today announced its financial results and business highlights for the fourth quarter and year ended December 31, 2013.

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

Cell-cycle arrest biomarkers validated for acute kidney injury

Saeed A. Jortani, Ph.D., associate clinical professor in the University of Louisville's Department of Pathology and Laboratory Medicine, headed up one of three labs in the United States involved in determining two new markers for acute kidney injury (AKI). The research group's paper, "Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication," was posted online Feb. 25 by the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2014

Study: Facebook use may increase risk of eating disorders, low self-esteem

Facebook has become a global phenomenon and an active space for social comparison. With the increase in technology use, there is a positive correlation with decreased body image in young women.

5 Mar 2014

Blast exposure may cause brain damage even without symptoms of TBI

Veterans exposed to explosions who do not report symptoms of traumatic brain injury (TBI) may still have damage to the brain's white matter comparable to veterans with TBI, according to researchers at Duke Medicine and the U.S. Department of Veterans Affairs.

4 Mar 2014

Researchers identify drug using yeast model that reduces levels of toxic protein in brains of AD patients

Using a yeast model of Alzheimer's disease (AD), Whitehead Institute researchers have identified a drug that reduces levels of the toxic protein fragment amyloid-β (Aβ) and prevents at least some of the cellular damage caused when Aβ accumulates in the brains of AD patients.

4 Mar 2014

Majority of women experience reproductive coercion and intimate partner violence

Enough women experience reproductive coercion - male behavior to control contraception and pregnancy outcomes - that a research team now recommends health care providers address the subjects with their patients and tailor family planning discussions and recommendations accordingly.

4 Mar 2014

Five women scientists to receive ‘L’Oréal-UNESCO For Women in Science Awards'

On March 19th the L'Oréal Foundation and UNESCO will present the L'Oréal-UNESCO For Women in Science awards to five outstanding women scientists.

3 Mar 2014

Pathology News and Research

Further Reading

Scientists study how cancer spreads through the body

Parkinson disease patients with higher CSF experience faster cognitive decline

Oncologists use mathematical model to develop treatment plans for cancer patients

Decision-making accuracy can be improved by postponing onset of decision

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Tissue analysis near tumors holds promise for earlier detection, new treatments

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Treating long wait-times dictate long-term success of spinal cord stimulation therapy

Scientists identify important step toward shutting down growth of prostate cancer cells

New findings shed light on how gene mutation causes motor neurone disease

New drug is effective against superbug MRSA

Scientists reveal how a genetic code variation results in devastating brain diseases

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Cell-cycle arrest biomarkers validated for acute kidney injury

Study: Facebook use may increase risk of eating disorders, low self-esteem

Blast exposure may cause brain damage even without symptoms of TBI

Researchers identify drug using yeast model that reduces levels of toxic protein in brains of AD patients

Majority of women experience reproductive coercion and intimate partner violence

Five women scientists to receive ‘L’Oréal-UNESCO For Women in Science Awards'

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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