Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

UC Irvine researchers create new stem cell-derived cell type for treatment of Alzheimer's

UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

8 Nov 2012

Studies shake up Alzheimer’s hypotheses

Two studies in people at genetic risk for Alzheimer’s disease reveal very early changes in brain structure and function that may actually precede amyloid beta deposition.

6 Nov 2012

Comprehensive overview of vascular risk factors to Alzheimer's disease

Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer's disease.

6 Nov 2012

Researchers analyse hydrogen bonds in tiny fibrils of amyloid-beta peptide

Using solid-state nuclear magnetic resonance (NMR) spectroscopy, researchers at Luleå University of Technology in collaboration with Warwick University in the UK for the first time in the world managed to analyse hydrogen bonds in tiny fibrils of Amyloid-beta peptide , which probably causes Alzheimer's disease.

5 Nov 2012

PET scans allow scientists to study link between caffeine and neurodegenerative disorders

Molecular imaging with positron emission tomography (PET) has enabled scientists for the first time to visualize binding sites of caffeine in the living human brain to explore possible positive and negative effects of caffeine consumption.

2 Nov 2012

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease.

2 Nov 2012

Blocking hyaluronidase activity can help repair brain damage associated with MS

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

1 Nov 2012

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel central nervous system (CNS) therapies, today presented pharmacokinetic and pharmacodynamic data along with the previously reported statistically significant clinical results from its Phase 2b clinical trial of EVP-6124, a novel alpha-7 agonist, in patients with Alzheimer's disease.

1 Nov 2012

Integra Holdings, a biopharmaceutical holding company, announced by Yissum

Yissum Research and Development Company of the Hebrew University of Jerusalem, the technology transfer company of the Hebrew University, announced today the inception of its subsidiary, Integra Holdings, a holding company focusing on biopharmaceutical companies based on inventions of researchers from the Hebrew University.

31 Oct 2012

Children with migraine more likely to have below average school performance

Children with migraine are more likely to have below average school performance than kids who do not have headaches, according to new research published in the October 30, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

30 Oct 2012

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

A novel, orally administered drug candidate, TTP488, has demonstrated clinical evidence of slowing of cognitive decline over 18 months of therapy in patients with mild to moderate Alzheimer's disease.

30 Oct 2012

Notable Medicare lawsuit settlement could aid patients needing skilled nursing care, other types of therapy

News outlets explain how a recent Medicare settlement could have an important impact on people who need physical, occupational and other therapies for certain disabilities and chronic conditions.

30 Oct 2012

First Edition: October 29, 2012

Today's headlines include reports about how the presidential election's outcome could impact the insurance industry as well as the fate of people who are sick or uninsured.

29 Oct 2012

Scientists identify grid cells in the brains of rhesus monkeys

Primates' brains see the world through triangular grids, according to a new study published online Sunday in the journal Nature.

29 Oct 2012

Researchers discover that bean commonly used in Chinese cuisine protects against sepsis

Researchers at The Feinstein Institute for Medical Research have discovered that a bean commonly used in Chinese cuisine protects against the life-threatening condition sepsis.

29 Oct 2012

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD).

29 Oct 2012

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

29 Oct 2012

ApoE4 gene becomes less important to quality of life once people hit their 90s

A gene linked to the risk of developing Alzheimer's, heart disease and diabetes becomes less important to quality of life once people hit their 90s, a Mayo Clinic study shows. At that point, good friends and a positive attitude have a bigger impact, the researchers say.

26 Oct 2012

Feinstein Institute to study overall impact of WTC disaster on responders

The Feinstein Institute for Medical Research has been awarded a $1 million grant from the World Trade Center Health Program, which is administered by the National Institute for Occupational Safety and Health, part of the US Centers for Disease Control and Prevention, the National Institute for Occupational Safety and Health and Safety to comprehensively study the overall physical, mental and socioeconomic impact of the World Trade Center (WTC) disaster on responders, as well as identify the linkage between socioeconomic status and health among all occupations of WTC responders.

26 Oct 2012

Three new gene variants associated with BMI levels in adults

A large international study has identified three new gene variants associated with body mass index (BMI) levels in adults. The scientific consortium, numbering approximately 200 researchers, performed a meta-analysis of 46 studies, covering gene data from nearly 109,000 adults, spanning four ethnic groups.

26 Oct 2012

Alzheimer's Disease News and Research

Further Reading

UC Irvine researchers create new stem cell-derived cell type for treatment of Alzheimer's

Studies shake up Alzheimer’s hypotheses

Comprehensive overview of vascular risk factors to Alzheimer's disease

Researchers analyse hydrogen bonds in tiny fibrils of amyloid-beta peptide

PET scans allow scientists to study link between caffeine and neurodegenerative disorders

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Blocking hyaluronidase activity can help repair brain damage associated with MS

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

Integra Holdings, a biopharmaceutical holding company, announced by Yissum

Children with migraine more likely to have below average school performance

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

Notable Medicare lawsuit settlement could aid patients needing skilled nursing care, other types of therapy

First Edition: October 29, 2012

Scientists identify grid cells in the brains of rhesus monkeys

Researchers discover that bean commonly used in Chinese cuisine protects against sepsis

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

ApoE4 gene becomes less important to quality of life once people hit their 90s

Feinstein Institute to study overall impact of WTC disaster on responders

Three new gene variants associated with BMI levels in adults

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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