Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Study demonstrates effectiveness of NeuroStar TMS Therapy System in women with postpartum depression

An unfortunate fact facing mothers in the U.S. is that postpartum depression is the most common complication of childbirth. Approximately 10 to 15 percent of women who give birth each year – or roughly 600,000 women – experience postpartum depression symptoms.

18 May 2016

Magic mushroom compound may offer potential new way for antidepressant research

Psilocybin – a hallucinogenic compound derived from magic mushrooms – may offer a possible new avenue for antidepressant research, according to a new study published in The Lancet Psychiatry today.

17 May 2016

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Repeat intravenous treatment with low doses of the anesthetic drug ketamine quickly reduced suicidal thoughts in a small group of patients with treatment-resistant depression.

11 May 2016

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that mindfulness based cognitive therapy (MBCT) is most helpful when antidepressant drugs are not used.

10 May 2016

Formal mental health therapies offer little relief from postpartum depression for low-income mothers of color

Health care providers and human service agencies often manage postpartum depression with formal mental health treatments and antidepressant therapies, but for new, low-income mothers of color these interventions often provide little relief from the mood disorder that sometimes follows childbirth, according to a new study led by a University at Buffalo researcher.

5 May 2016

High-intensity exercise, group activity reduce depression among older dementia patients

Both a high-intensity functional exercise programme and a non-exercise group activity, conducted among older care facility residents with dementia, reduced high levels of depressive symptoms. However, exercise had no superior effect on depression, according to a dissertation from Umea University.

3 May 2016

Exposure to SSRI during gestation increases chances of adolescent offspring depression

A study to be published in the May 2016 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) reports that use of certain antidepressants during pregnancy can result in offspring depression by early adolescence.

28 Apr 2016

MBCT could be effective treatment to prevent recurrence of depression

The largest meta-analysis so far of Mindfulness-Based Cognitive Therapy (MBCT) for recurrent depression has found that MBCT is an effective treatment option that can help prevent the recurrence of major depression. The study used anonymised individual patient data from nine randomized trials of MBCT. It suggests that for the millions of people who suffer recurrent depression it provides a treatment choice and an alternative or addition to other approaches such as maintenance anti-depressants.

28 Apr 2016

Nutritional supplements can enhance effectiveness of antidepressants

An international evidence review has found that certain nutritional supplements can increase the effectiveness of antidepressants for people with clinical depression.

26 Apr 2016

Antidepressant Wellbutrin linked to long-term modest weight loss

Group Health researchers have found that bupropion (marketed as Wellbutrin) is the only antidepressant that tends to be linked to long-term modest weight loss.

21 Apr 2016

Study explores effectiveness of cognitive behavioral therapy in primary care for depressed teenagers

Depressed teenagers who received cognitive behavioral therapy in their primary care clinic recovered faster, and were also more likely to recover, than teens who did not receive the primary care-based counseling, according to a Kaiser Permanente study published today in the journal Pediatrics.

21 Apr 2016

Depression combined with behavioral, metabolic symptoms increases risk of type 2 diabetes

Depression may compound the risk of developing type 2 diabetes in people with such early warning signs of metabolic disease as obesity, high blood pressure and unhealthy cholesterol levels, according to researchers from McGill University, l'Université de Montréal, the Institut de recherches cliniques de Montréal and the University of Calgary.

13 Apr 2016

Long-term medication use reduces risk of relapse and improves symptoms in BDD patients

People with Body Dysmorphic Disorder (BDD) fare better and are less likely to relapse when treated with medication on a long-term basis, according to researchers at Rhode Island Hospital and Massachusetts General Hospital.

11 Apr 2016

Northwestern Medicine study reveals psychotherapy can alleviate genetically depressed rats

Genes are not destiny in determining whether an individual will suffer from depression, reports a new Northwestern Medicine study. Environment is a major factor, and nurture can override nature.

30 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Parent, caregiver's depression linked to worsening symptoms in asthmatic child

Studies have shown that children with asthma are at higher risk for depression. Research also has shown an association between a parent or caregiver's depression and worsening symptoms in an asthmatic child.

14 Mar 2016

Antidepressants may play role in dental implant failure

Antidepressants, commonly used to treat anxiety, pain and other disorders, may play a role in dental implant failure, according to a new pilot study by University at Buffalo researchers.

8 Mar 2016

New study assesses link between depression, anxiety and antidepressants and outcome of IVF

Depression and anxiety, and not necessarily the use of antidepressant medication, are associated with lower pregnancy and live birth rates following in vitro fertilisation, according to a large register study from Karolinska Institutet in Sweden. The findings are published in the journal Fertility & Sterility and can be of interest to clinicians treating infertility and for women with depression or anxiety planning to undergo fertility treatment.

8 Mar 2016

Antidepressant initiation more frequent among people with Alzheimer's disease even before diagnosis

Antidepressants are frequently initiated in persons with Alzheimer's disease already before the diagnosis, shows a recent study from the University of Eastern Finland. Among persons with Alzheimer's disease, the initiation of antidepressant use was most common during the six months after the Alzheimer's diagnosis, and more frequent than among comparison persons without Alzheimer's disease even 4 years after the diagnosis. The results were published in International Journal of Geriatric Psychiatry.

4 Mar 2016

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016