Electron Microscopy News and Research

RSS

Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt crystals do occur even at low salt concentrations in nanoscales, and that it can accelerate the aggregation of the neurotoxic amyloid-β peptides implicated in its pathogenesis.

27 Jul 2020

Study captures unexpected features of SARS-Cov-2 spike protein

The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the COVID-19 pandemic.

22 Jul 2020

Harvard scientists uncover the real reason behind goosebumps

If you've ever wondered why we get goosebumps, you're in good company -- so did Charles Darwin, who mused about them in his writings on evolution.

20 Jul 2020

Involvement of nicotine receptors in COVID-19

Researchers from the University of Bristol, Oxford Brookes University and the University of California San Diego neatly demonstrated how the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits high affinity for nicotinic acetylcholine receptors (nAChRs), with significant implications for coronavirus disease (COVID-19) pathology and infectivity. Their findings are published on the bioRxiv* preprint server.

20 Jul 2020

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

An interdisciplinary team from Frankfurt and Jena has developed a kind of bait with which to fish protein complexes out of mixtures.

20 Jul 2020

Researchers determine how SARS-CoV-2 inhibits protein synthesis

Researchers from Munich and Ulm have determined how the pandemic coronavirus SARS-CoV-2 inhibits the synthesis of proteins in infected cells and shown that it effectively disarms the body's innate immune system.

19 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Pioneering method reveals the dynamics of HIV Gag lattice structure

Viruses are scary. They invade our cells like invisible armies, and each type brings its own strategy of attack. While viruses devastate communities of humans and animals, scientists scramble to fight back.

16 Jul 2020

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

Researchers at Duke University in Durham, USA, have made an important discovery about the spike protein on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could have a broad impact on vaccine studies.

14 Jul 2020

UQ researchers reveal three-dimensional structure of important enzyme

Advanced herbicides and treatments for infection may result from the unravelling of a 50-year-old mystery by University of Queensland researchers.

11 Jul 2020

Study shows how plants operate on a molecular level

New research from the University of Virginia School of Medicine reveals how plants create the load-bearing structures that let them grow - much like how building crews frame a house.

10 Jul 2020

Structure of the SARS-CoV-2 spike protein provides clues to its evolution

Researchers at the Francis Crick Institute have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.

9 Jul 2020

SARS-CoV-2 spike protein hidden as pH changes

Now, a new study published on the preprint server bioRxiv in July 2020 reports the role of pH in helping the virus escape neutralization by antibodies, by inducing a key conformational switch.

7 Jul 2020

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack.

6 Jul 2020

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress - a new study confirms.

3 Jul 2020

Researchers isolate protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

3 Jul 2020

New study supports a causal relation of SARS-CoV-2 with COVID toes

There's considerable controversy over whether "COVID toes"—red sores or lesions on the feet and hands in children and young adults—are truly caused by COVID-19.

2 Jul 2020

Interactive cloud-based data portal provides access to treasure trove of pediatric solid tumor data

An innovative, interactive cloud-based data portal debuted this week that lets academic researchers mine the world's largest and most comprehensive collection of scientific resources for studying pediatric solid tumors and their related biology.

26 Jun 2020

Effective neutralization of SARS-CoV-2 by synthetic nanobodies targeting the spike protein

In their recent bioRxiv paper, a multinational group of researchers reported rapid isolation and characterization of nanobodies from a synthetic library (known as sybodies) that target the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein – with a strikingly high neutralization ability.

24 Jun 2020

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

A seminal study by US researchers, currently available on the bioRxiv* preprint server, demonstrates how structure-based design can be efficiently employed to develop molecular probes targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike and its domains, with possible future use in diagnostics, treatment and vaccine development.

24 Jun 2020

Electron Microscopy News and Research

Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Study captures unexpected features of SARS-Cov-2 spike protein

Harvard scientists uncover the real reason behind goosebumps

Involvement of nicotine receptors in COVID-19

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

Researchers determine how SARS-CoV-2 inhibits protein synthesis

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Pioneering method reveals the dynamics of HIV Gag lattice structure

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

UQ researchers reveal three-dimensional structure of important enzyme

Study shows how plants operate on a molecular level

Structure of the SARS-CoV-2 spike protein provides clues to its evolution

SARS-CoV-2 spike protein hidden as pH changes

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

Researchers isolate protective antibodies for rare, polio-like disease in children

New study supports a causal relation of SARS-CoV-2 with COVID toes

Interactive cloud-based data portal provides access to treasure trove of pediatric solid tumor data

Effective neutralization of SARS-CoV-2 by synthetic nanobodies targeting the spike protein

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

Life Science Microscopy eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News