Living Cells News and Research

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Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces and Metrology 17 Oct 2017

Dietary supplement could be promising therapeutic target for seizure disorders

Seizure disorders -- including epilepsy -- are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability.

13 Oct 2017

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.

13 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

UNLV researchers develop new method for extracting large numbers of stem cells from wisdom teeth

Stem cells. Few research discoveries hold as much promise of single-handedly expanding medical treatment options as they do. Miraculously able to act as transformers - either re-creating or morphing into a variety of cell types found within the organisms they originate from - stem cells offer humanity hope for new, more effective therapies against a number of chronic and terminal diseases. And finding them is surprisingly easy.

4 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

IUPUI cell biologist receives $1.9 million grant to tackle age-related hearing loss

Cell biologist Benjamin J. Perrin of the School of Science at Indiana University-Purdue University Indianapolis is advancing knowledge of age-related hearing loss with the goal of informing possible therapeutic cell-regeneration approaches to the often-debilitating problem.

14 Sep 2017

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

Using a microscope invented at the Marine Biological Laboratory (MBL), a collaborative team of biologists, instrument developers, and computational scientists has for the first time measured the density of a relatively inscrutable, highly condensed form of chromosomal material that appears in the cells of human beings and other eukaryotes.

13 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

For several decades, scientists have recognized the key role that a molecule known as GTP, one of the building blocks of RNA, plays in the development of cancer and other diseases.

13 Sep 2017

Optical Microscopy Resolution Revolution

I will talk about the simple but fundamental idea that allowed breaking the diffraction barrier in fluorescence microscopy as well as about MINFLUX nanoscopy, the latest development in the field that for the first time provides true molecular resolution with visible light and standard objective lenses.

From Pittcon 12 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Scientists uncover stem cell response to prolonged irradiation

Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells.

24 Aug 2017

Chemist develops new sugar-coated probe to easily detect low pH in living cells

The human body is engaged in a constant tightrope walk to maintain the right pH, because when our cells' acid-alkaline balance goes wrong, it can go wrong in a big way.

11 Aug 2017

Pitt researcher aims to develop 'smart biomaterials' for reprogramming mammalian cell signaling

Through a process called cell signaling, cells collaborate on necessary functions such as responding to changes in the environment, fighting off threats to the body, or regulating the basic processes that keep the body alive.

4 Aug 2017

UMD scientists develop new bio-compatible ionic current-generating battery

Engineers at the University of Maryland have invented an entirely new kind of battery. It is bio-compatible because it produces the same kind of ion-based electrical energy used by humans and other living things.

24 Jul 2017

Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Scientists gain new insights into protein network that regulates programmed cell death

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases.

14 Jul 2017

Living Cells News and Research

Using AFM to study cell mechanics and function

Dietary supplement could be promising therapeutic target for seizure disorders

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

MIT researchers develop new technique to screen for genes that protect against diseases

UNLV researchers develop new method for extracting large numbers of stem cells from wisdom teeth

Scientists manipulate living cells to produce fluorinated bioplastics

Researchers produce fluorinated molecules in living cells

Analytical Science in Precision Medicine

IUPUI cell biologist receives $1.9 million grant to tackle age-related hearing loss

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

Optical Microscopy Resolution Revolution

Seeing the full picture, real-time analysis of live-cells

Scientists uncover stem cell response to prolonged irradiation

Chemist develops new sugar-coated probe to easily detect low pH in living cells

Pitt researcher aims to develop 'smart biomaterials' for reprogramming mammalian cell signaling

UMD scientists develop new bio-compatible ionic current-generating battery

Scientists manage to permeate living cells with small antibodies

Scientists gain new insights into protein network that regulates programmed cell death

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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