Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Study provides new insight into causes of rare metabolic disorder

Just before Rare Disease Day 2017, a study from the Monell Center and collaborating institutions provides new insight into the causes of trimethylaminura, a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish.

14 Feb 2017

Scientists discover reason behind mosquitoes’ attraction towards people with malaria

Malaria mosquitoes prefer to feed -- and feed more -- on blood from people infected with malaria. Researchers from Stockholm University, the Swedish University of Agricultural Sciences and KTH Royal Institute of Technology have discovered why.

9 Feb 2017

Adjusting KYNA levels can have significant effects on schizophrenia-like behavior, mice study finds

A new study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia-like behavior. The study appeared in the latest issue of the journal Biological Psychiatry.

7 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered.

19 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread.

1 Dec 2016

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.

29 Nov 2016

Metabolomics research at the Phenome Centre Birmingham

An interview with Professor Mark Viant, University of Birmingham, UK, Executive Director of Phenome Centre Birmingham and Director of the NERC Biomolecular Analysis Facility.

From Bruker BioSpin - NMR, EPR and Imaging 28 Nov 2016

Stuttering linked to changes in speech and language-based brain circuits

Researchers at Children's Hospital Los Angeles have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter.

23 Nov 2016

Researchers develop new rapid diagnostic test for cocaine in urine and oral fluid

Academics in the University of Surrey's Department of Chemistry have developed a new diagnostic test for cocaine and benzoylecgonine (the main metabolite for cocaine) in urine and oral fluid.

21 Nov 2016

New bioinformatic framework identifies protein that plays key role in diabetic kidney disease

A new bioinformatic framework developed by researchers at University of California San Diego School of Medicine has identified key proteins significantly altered at the gene-expression level in biopsied tissue from patients with diabetic kidney disease, a result that may reveal new therapeutic targets.

16 Nov 2016

Researchers develop new blood test that can accurately diagnose concussions

Scientists from Children's Health Research Institute, a program of Lawson Health Research Institute, and Western University have developed a new blood test that identifies with greater than 90 per cent certainty whether or not an adolescent athlete has suffered a concussion.

7 Nov 2016

Metabolite News and Research

Further Reading

Study provides new insight into causes of rare metabolic disorder

Scientists discover reason behind mosquitoes’ attraction towards people with malaria

Adjusting KYNA levels can have significant effects on schizophrenia-like behavior, mice study finds

Researchers identify new mechanism that protects from bacterial infections

Researcher develops new method to accurately identify elusive molecules

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Research unlocks potential new therapies for inflammatory diseases

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Metabolomics research at the Phenome Centre Birmingham

Stuttering linked to changes in speech and language-based brain circuits

Researchers develop new rapid diagnostic test for cocaine in urine and oral fluid

New bioinformatic framework identifies protein that plays key role in diabetic kidney disease

Researchers develop new blood test that can accurately diagnose concussions

Researchers identify potential approach for preventing neurological problems caused by blast-related TBI

Study shows metabolite concentration can be controlled in bioreactors using OPC enabled BioProfile FLEX analyser

Choline deficiency in sows during pregnancy impacts nutrient composition of milk

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

New lab-on-a-chip system can detect effects of toxic substances on hemoglobin in blood

Unknown exposure to second-hand smoke linked to increased mortality in non-smokers

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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