Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

CHMP recommends approval of Gilenya for treatment of multiple sclerosis in children, adolescents

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended approval of Gilenya (fingolimod) for the treatment of children and adolescents 10 to 17 years of age with relapsing remitting forms of multiple sclerosis.

24 Sep 2018

New therapeutic vaccine helps immune cells fight HPV-related head and neck cancer

A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus-related head and neck cancer.

24 Sep 2018

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

A clinical trial testing infusions of combination antibodies in people living with HIV has begun at the National Institutes of Health.

20 Sep 2018

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

Sesen Bio, Inc., a late-stage clinical company developing fusion protein therapies for the treatment of cancer, today announced that the company will present its three-month Phase 3 VISTA Trial data during a poster session at the Global Congress on Bladder Cancer 2018.

20 Sep 2018

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

An analysis of the NRG Oncology clinical trial NRG-GY003 suggests that adding ipilimumab, a monoclonal antibody that targets the protein receptor CTLA-4, to a regimen with the checkpoint inhibitor nivolumab could improve the proportion with tumor response and progression-free survival hazard rates for women with recurrent epithelial ovarian cancer.

19 Sep 2018

Alector announces initiation of Phase 1 trial of AL001 for treating frontotemporal dementia

Alector, a privately held biotechnology company pioneering immuno-neurology, a novel therapeutic approach for the treatment of neurodegeneration, today announced the initiation of its Phase 1 trial called INFRONT, which is evaluating AL001, the company's product candidate for the treatment of a genetically-defined sub-population of patients with frontotemporal dementia.

19 Sep 2018

Purifying Proteins from Mammalian Cell Culture

In many cases mammalian cells are the only option to produce recombinant proteins with correct post-translational modifications, e.g. glycosylation, which are required for proper function of the therapeutic protein.

From Sartorius 18 Sep 2018

Amyloid β protein makes comeback as therapeutic target for Alzheimer's disease

For many years amyloid β protein was considered to be a promising therapeutic target in Alzheimer's disease but, for a long time, research results were very disappointing.

18 Sep 2018

LEO Pharma and MorphoSys announce expansion of strategic alliance to develop peptide-derived drugs

LEO Pharma A/S, a global leader in medical dermatology, and MorphoSys AG today announced an expansion of their existing strategic alliance to include peptide-derived therapeutics.

18 Sep 2018

Investigational nasal influenza vaccine tested in children and teens

An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit site at Saint Louis University, St. Louis, Missouri.

17 Sep 2018

New discovery could improve diagnosis and treatment of lupus in black Africans

Two variants of an autoimmune disease that affects thousands but is hard to diagnose are relatively common among black Africans, research shows.

17 Sep 2018

Researchers develop new blood test to detect early stage pancreatic cancer

Pancreatic cancer is currently very difficult to detect while it is still resectable. A new blood test developed by researchers at Lund University in Sweden, Herlev Hospital, Knight Cancer Center and Immunovia AB, can detect pancreatic cancer in the very earliest stages of the disease.

17 Sep 2018

FDA approves Teva’s AJOVY injection for preventive treatment of migraine in adults

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has approved AJOVY injection for the preventive treatment of migraine in adults.

17 Sep 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Researchers describe mechanism that sets stage for fate decision of T cells

After a pathogen infects the body, the immune system responds with a remarkable -- and remarkably complicated -- cascade of events.

14 Sep 2018

Rare antibodies could be key ingredients in therapeutics capable of neutralizing many Ebola types

Two new studies by scientists at Scripps Research are bringing Ebola virus's weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection--not only for Ebola virus, but for other closely related pathogens as well.

13 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

Discovery provides new hope for anti-HIV vaccine

Researchers have discovered that the RNA genome of the HIV virus can influence the immune response generated, and thus influence human survival.

10 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Neutrophil nanosponges provide hope for rheumatoid arthritis

Scientists in San Diego have developed nanosponges coated in neutrophil membranes that can prevent rheumatoid arthritis.

3 Sep 2018

Antibody News and Research

Further Reading

CHMP recommends approval of Gilenya for treatment of multiple sclerosis in children, adolescents

New therapeutic vaccine helps immune cells fight HPV-related head and neck cancer

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

Alector announces initiation of Phase 1 trial of AL001 for treating frontotemporal dementia

Purifying Proteins from Mammalian Cell Culture

Amyloid β protein makes comeback as therapeutic target for Alzheimer's disease

LEO Pharma and MorphoSys announce expansion of strategic alliance to develop peptide-derived drugs

Investigational nasal influenza vaccine tested in children and teens

New discovery could improve diagnosis and treatment of lupus in black Africans

Researchers develop new blood test to detect early stage pancreatic cancer

FDA approves Teva’s AJOVY injection for preventive treatment of migraine in adults

FDA approves new treatment for people with hairy cell leukemia

Researchers describe mechanism that sets stage for fate decision of T cells

Rare antibodies could be key ingredients in therapeutics capable of neutralizing many Ebola types

Mouse study suggests new therapeutic approach to treat heart failure

Discovery provides new hope for anti-HIV vaccine

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Neutrophil nanosponges provide hope for rheumatoid arthritis

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