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Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Close to 70 percent of men with erectile dysfunction (ED) respond to the ED drug sildenafil. However, only about 50 percent of men with diabetes- a population commonly affected by ED- achieve positive results with sildenafil.

6 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

New research could reduce recurrence of prostate cancer

Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.

5 Sep 2017

New discovery suggests choanos ‘eavesdrop’ on bacteria to regulate their life history

To the surprise of scientists, bacteria can act as an aphrodisiac for one-celled marine organisms notable for being the closest living relative of all animals.

1 Sep 2017

Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

Researcher uses gold nanoparticles and lasers to target bladder cancer

A University of Colorado Cancer Center study takes a new approach to killing cancer: Why not fry it into oblivion with vibrating gold nanoparticles? "But what about the frickin' lasers?" you may ask. Don't worry. There are lasers. And bioluminescence too.

31 Aug 2017

New drug shows promise to treat women with estrogen positive metastatic breast cancer

Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease.

31 Aug 2017

Researchers decipher how some Listeria strains survive high food hygiene standards

Listeria monocytogenes is a foodborne pathogen that colonizes and reproduces on diverse food products including cheese or meat.

30 Aug 2017

HHMI scientists expand access to new resource for studying pediatric cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

30 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Traditional Chinese herb may hold key to new osteoporosis therapy for preventing bone loss

An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.

29 Aug 2017

Pathway from ADI to AUD symptoms influenced by ethnicity and genetics

Studies have shown that an early age of drinking initiation (ADI) increases the chance of developing an alcohol use disorder (AUD).

29 Aug 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Enzyme News and Research

Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Scientists show how receptors for drugs act inside cells

New research could reduce recurrence of prostate cancer

New discovery suggests choanos ‘eavesdrop’ on bacteria to regulate their life history

Scientists question CRISPR human embryo editing claims

St. Jude creates world’s largest collection of pediatric solid tumor samples

Researcher uses gold nanoparticles and lasers to target bladder cancer

New drug shows promise to treat women with estrogen positive metastatic breast cancer

Researchers decipher how some Listeria strains survive high food hygiene standards

HHMI scientists expand access to new resource for studying pediatric cancers

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Traditional Chinese herb may hold key to new osteoporosis therapy for preventing bone loss

Pathway from ADI to AUD symptoms influenced by ethnicity and genetics

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Biomedical engineering researchers aim to attack two banes of cardiovascular disease

Research paves way for new drugs that may prevent tumor repopulation after radiation therapy

CSUDH professor seeks novel lead compound to develop new drug for treating cancer

Scientists develop new system to identify and characterize regulatory DNA sequences

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

Rare transition metal can simplify design and preparation of antibody therapies

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo