Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study reveals atomic-level structure of the human peptidase enzyme meprin β

An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic-level structure of the human peptidase enzyme meprin β (beta).

5 Oct 2012

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

New research proves the validity of one of the most promising approaches for combating Alzheimer's disease (AD) with medicines that treat not just some of the symptoms, but actually stop or prevent the disease itself, scientists are reporting. The study, in the journal ACS Medicinal Chemistry Letters, also identifies a potential new oral drug that the scientists say could lead the way.

5 Oct 2012

Mexiletine improves patient-reported stiffness in nondystrophic myotonia

An older medication originally approved to treat heart problems eases the symptoms of a very rare muscle disease that often leaves its sufferers stiff and in a good deal of pain, physicians and researchers report in the Oct. 3 issue of the Journal of the American Medical Association.

4 Oct 2012

New nanodevice lays foundations for future development of novel therapies against aging

A team of Spanish scientists has developed an intelligent nanodevice that lays the foundations for the future development of new therapies against aging. The device consists of nanoparticles that can selectively release drugs in aged human cells.

4 Oct 2012

Georgia Tech's ClockMe system helps older adults identify early signs of dementia

With baby boomers approaching the age of 65 and new cases of Alzheimer's disease expected to increase by 50 percent by the year 2030, Georgia Tech researchers have created a tool that allows adults to screen themselves for early signs of dementia. The home-based computer software is patterned after the paper-and-pencil Clock Drawing Test, one of health care's most commonly used screening exams for cognitive impairment.

4 Oct 2012

Lecture to discuss insights into genes and neurodegenerative diseases gleaned from baker's yeast

Insights into our genes and neurodegenerative diseases gleaned from humble baker's yeast, among other things, will be showcased by genetics experts at a free public lecture.

4 Oct 2012

UMass Amherst biophysicist receives 2013 Margaret Oakley Dayhoff Award

University of Massachusetts Amherst biophysicist Jenny Ross has won one of the top national honors in her field, the 2013 Margaret Oakley Dayhoff Award, from the Biophysical Society of Rockville, Md. It is given to a woman who has achieved prominence for "substantial contributions to science," while showing very high promise for ideas and leadership in the early stages of her biophysical research career.

3 Oct 2012

New mouse model could foster ALS, Paget's and dementia breakthroughs

Efforts to treat disorders like Lou Gehrig's disease, Paget's disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.

3 Oct 2012

Low serum levels of IGF-1 and IGFBP-3 associated with Alzheimer's in men

Low serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) are associated with Alzheimer's Disease in men, but not women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Oct 2012

Obesity from high-energy diets may impair brain, fuel overeating

"Betcha can't eat just one!" For obese people trying to lose weight, the Lays potato chip advertising slogan hits a bit too close to home as it describes the daily battle to resist high calorie foods.

3 Oct 2012

Memory impairments linked to object perception among people with early stage Alzheimer's

A new study from Georgia Tech and the University of Toronto suggests that memory impairments for people diagnosed with early stage Alzheimer's disease may be due, in part, to problems in determining the differences between similar objects.

2 Oct 2012

Omega-3 fatty acid supplements could slow key biological process linked to aging

Taking enough omega-3 fatty acid supplements to change the balance of oils in the diet could slow a key biological process linked to aging, new research suggests.

2 Oct 2012

Common RNA pathway links frontotemporal lobar dementia with ALS

Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine, shows that a common pathway links them.

1 Oct 2012

Rapamycin can alleviate frontotemporal lobar degeneration

A southern Taiwan-based National Cheng Kung University (NCKU) research team has discovered that rapamycin, a drug as a autophagy activator is a possible treatment to alleviating frontotemporal lobar degeneration (FTLD), one of the mainly causes of dementia, and so far no medication can be used.

29 Sep 2012

Longer looks: In-depth in the ER; Brains are saved as high school football season begins

Eric Morgan, in his 20s and planning to get married, arrives at Highland Hospital's emergency room, shaken that he has been diagnosed with a testicular tumor that is likely cancer. Surgeons at a private hospital have turned him away for lack of insurance but tell him it's "urgent" he get care.

28 Sep 2012

CJD presents major diagnostic problems

Most patients with sporadic Creutzfeldt-Jakob disease are initially misdiagnosed, with most not receiving a correct diagnosis until they are two-thirds of the way through their disease course, show findings in the Archives of Neurology.

27 Sep 2012

Combination of two neuroprotective therapies shows promise against Alzheimer's

The combination of two neuroprotective therapies, voluntary physical exercise, and the daily intake of melatonin has been shown to have a synergistic effect against brain deterioration in rodents with three different mutations of Alzheimer's disease.

27 Sep 2012

Accera to sponsor National Memory Screening Day of Alzheimer's Foundation of America

Accera, Inc., a privately-held, commercial-stage, healthcare company focused on the discovery and development of innovative clinical applications to address acute and chronic neurodegenerative diseases, announced today that it is a silver sponsor of the Alzheimer's Foundation of America's (AFA) National Memory Screening Day (NMSD) on November 13, 2012 during National Alzheimer's Disease Awareness Month.

27 Sep 2012

Assisted Living Federation of America launches Stop Alzheimer's Petition

Today the Assisted Living Federation of America (ALFA) has launched the Stop Alzheimer's Petition, which urges the President of the United States and members of Congress to make preventing and effectively treating Alzheimer's disease and other forms of dementia a priority on Capitol Hill.

27 Sep 2012

Adult stem cells can prevent Alzheimer's disease

In the first study of its kind, researchers at Korea's leading university and the RNL Bio Stem Cell Technology Institute announced this week the results of a study that suggests an astounding possibility: adult stem cells may not only have a positive effect on those suffering from Alzheimer's disease, they can prevent the disease.

27 Sep 2012

Alzheimer's Disease News and Research

Further Reading

Study reveals atomic-level structure of the human peptidase enzyme meprin β

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

Mexiletine improves patient-reported stiffness in nondystrophic myotonia

New nanodevice lays foundations for future development of novel therapies against aging

Georgia Tech's ClockMe system helps older adults identify early signs of dementia

Lecture to discuss insights into genes and neurodegenerative diseases gleaned from baker's yeast

UMass Amherst biophysicist receives 2013 Margaret Oakley Dayhoff Award

New mouse model could foster ALS, Paget's and dementia breakthroughs

Low serum levels of IGF-1 and IGFBP-3 associated with Alzheimer's in men

Obesity from high-energy diets may impair brain, fuel overeating

Memory impairments linked to object perception among people with early stage Alzheimer's

Omega-3 fatty acid supplements could slow key biological process linked to aging

Common RNA pathway links frontotemporal lobar dementia with ALS

Rapamycin can alleviate frontotemporal lobar degeneration

Longer looks: In-depth in the ER; Brains are saved as high school football season begins

CJD presents major diagnostic problems

Combination of two neuroprotective therapies shows promise against Alzheimer's

Accera to sponsor National Memory Screening Day of Alzheimer's Foundation of America

Assisted Living Federation of America launches Stop Alzheimer's Petition

Adult stem cells can prevent Alzheimer's disease

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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