Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers identify mechanism that appears to underlie non-familial form of Parkinson's

Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement disorder.

26 Sep 2012

Fly neurons may uncover secrets of Alzheimer's disease

Although they're a common nuisance in the home, fruit flies have made great contributions to research in genetics and developmental biology. Now a Tel Aviv University researcher is again turning to this everyday pest to answer crucial questions about how neurons function at a cellular level - which may uncover the secrets of neurological disorders such as Alzheimer's disease.

26 Sep 2012

Researchers identify several kinase inhibitors that help generate many iPSCs

The process researchers use to generate induced pluripotent stem cells (iPSCs)-a special type of stem cell that can be made in the lab from any type of adult cell-is time consuming and inefficient. To speed things up, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) turned to kinase inhibitors.

26 Sep 2012

LifeBridge Health’s Center for Memory & Behavioral Disorders to be opened on Oct. 2

The Center for Memory & Behavioral Disorders at LifeBridge Health opens its doors on the campus of Levindale Hebrew Geriatric Center and Hospital on Tuesday, October 2 to provide comprehensive initial evaluation services to people with dementia and behavioral disorders.

25 Sep 2012

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness in reversing memory loss in two animal models of Alzheimer's disease.

25 Sep 2012

Alzheimer's can involve mixture of proteins from different neurodegenerative diseases

Neurodegenerative diseases such as Alzheimer's or Parkinson's are characterised by the loss of nerve cells and the deposition of proteins in the brain tissue. A group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has now demonstrated that Alzheimer's disease does not just - as previously believed - involve the proteins that are attributed to Alzheimer's, but instead the condition can involve a mixture of interacting proteins from different neurodegenerative diseases.

24 Sep 2012

Smoking, obesity and lack of insurance may be shortening life span for some Americans

The New York Times reports that the nation's life-expectancy trend has reversed by four years since 1990 for the country's least-educated whites.

21 Sep 2012

Simultaneous computer brain exercises and electromagnetic stimulation for Alzheimer's disease treatment

World Alzheimer's Day - As the planet turns its attention to World Alzheimer's Day, an emerging technology using focused computer brain exercises may offer new hope to Alzheimer's patients and their families.

21 Sep 2012

Childhood emotional neglect may increase risk of stroke in later adulthood

The results from a new study by neurological researchers from the Rush Alzheimer's Disease Center at Rush University Medical Center suggest that people who were emotionally neglected as children may have a higher risk of stroke in later adulthood.

21 Sep 2012

First extensive analysis of Allen Human Brain Atlas

Scientists at the Allen Institute for Brain Science reported in the latest issue of the journal Nature that human brains share a consistent genetic blueprint and possess enormous biochemical complexity. The findings stem from the first deep and large-scale analysis of the vast data set publicly available in the Allen Human Brain Atlas.

21 Sep 2012

Researchers use nanoparticles to deliver drugs to mitochondria within cells

Nanoparticles have shown great promise in the targeted delivery of drugs to cells, but researchers at the University of Georgia have refined the drug delivery process further by using nanoparticles to deliver drugs to a specific organelle within cells.

21 Sep 2012

Navidea commences enrollment in [18F]NAV4694 Phase 2 study for Alzheimer's

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that enrollment has commenced at two sites participating in its Phase 2, open-label, safety and efficacy PET imaging study of [18F]NAV4694 for detection of cerebral β-amyloid plaque in subjects diagnosed with probable Alzheimer's disease (AD).

19 Sep 2012

BACE2 enzyme could represent powerful new tool against Alzheimer's

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme - known as BACE2 - destroys beta-amyloid, a toxic protein fragment that litters the brains of patients who have the disease.

18 Sep 2012

Brain-healthy lifestyle may prevent symptoms of Alzheimer's

Alzheimer's disease is the sixth leading cause of death in the U.S., and that figure isn't going down. In fact, as America's older population grows, deaths from Alzheimer's continue to rise, and have increased 66 percent since 2000. If current population trends continue and no cure is found, the actual number of people living with the disease could double every 20 years.

18 Sep 2012

Healthcare costs could total more than household assets for elderly at end of life

For more than 25% of elderly US citizens, healthcare costs incurred during the last 5 years of life will amount to more than their total household assets, show data reported in the Journal of General Internal Medicine.

17 Sep 2012

VTT, GE Healthcare enter collaboration for AD research

Scientists from VTT Technical Research Centre of Finland in collaboration with the University of Eastern Finland have recently discovered a serum biochemical signature which predicts progression to Alzheimer's disease months or even years before the first symptoms of the disease occur. The goal of the new collaboration between VTT and GE Healthcare is to validate this biomarker in a large patient cohort as well as to discover novel biomarker candidates.

17 Sep 2012

Alzheimer's pathology might be increased in patients after surgery and anesthesia

A syndrome called "post-operative cognitive decline" has been coined to refer to the commonly reported loss of cognitive abilities, usually in older adults, in the days to weeks after surgery. In fact, some patients time the onset of their Alzheimer's disease symptoms from a surgical procedure.

15 Sep 2012

Brandeis University biology professor receives NIH Director's New Innovator award

Chances are you didn't spend much time this morning getting your shoes on or thinking about which route you would take to work. But for people suffering with debilitating diseases such as ALS (Lou Gehrig's disease) or Alzheimer's, such simple functions -- and even activities like breathing and eating -- can be a struggle.

15 Sep 2012

Experimental diabetes drug shows promise against Alzheimer's

A drug designed for diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer's, a study by scientists at the University of Ulster has revealed.

15 Sep 2012

Moderate exercise may help people cope with future anxiety and stress

Moderate exercise may help people cope with anxiety and stress for an extended period of time post-workout, according to a study by kinesiology researchers in the University of Maryland School of Public Health published in the journal Medicine and Science in Sports and Exercise.

14 Sep 2012

Alzheimer's Disease News and Research

Further Reading

Researchers identify mechanism that appears to underlie non-familial form of Parkinson's

Fly neurons may uncover secrets of Alzheimer's disease

Researchers identify several kinase inhibitors that help generate many iPSCs

LifeBridge Health’s Center for Memory & Behavioral Disorders to be opened on Oct. 2

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

Alzheimer's can involve mixture of proteins from different neurodegenerative diseases

Smoking, obesity and lack of insurance may be shortening life span for some Americans

Simultaneous computer brain exercises and electromagnetic stimulation for Alzheimer's disease treatment

Childhood emotional neglect may increase risk of stroke in later adulthood

First extensive analysis of Allen Human Brain Atlas

Researchers use nanoparticles to deliver drugs to mitochondria within cells

Navidea commences enrollment in [18F]NAV4694 Phase 2 study for Alzheimer's

BACE2 enzyme could represent powerful new tool against Alzheimer's

Brain-healthy lifestyle may prevent symptoms of Alzheimer's

Healthcare costs could total more than household assets for elderly at end of life

VTT, GE Healthcare enter collaboration for AD research

Alzheimer's pathology might be increased in patients after surgery and anesthesia

Brandeis University biology professor receives NIH Director's New Innovator award

Experimental diabetes drug shows promise against Alzheimer's

Moderate exercise may help people cope with future anxiety and stress

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