Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Annual Depression on College Campuses Conference to be held March 7-8

How can college students draw upon their own strengths, resilience, and sense of social connectedness to help them maintain mental health and wellness? Researchers, students and U-M community members will discuss this question at the annual Depression on College Campuses Conference, held March 7-8. The conference - which is marking its 10th anniversary - features workshops and sessions focused on reframing the discussion about mental health on college campuses by emphasizing the importance of student strengths in preventing depression.

2 Feb 2012

Leading medical groups collaborate to ensure consistent, responsible uptake of TAVR

With the U.S. Food and Drug Administration's recent approval of transcatheter aortic valve replacement (TAVR) for patients with aortic valvular stenosis, the American College of Cardiology Foundation (ACCF), along with the American Association for Thoracic Surgery (AATS), the Society for Cardiovascular Angiography and Interventions (SCAI) and the Society of Thoracic Surgeons (STS), today released an expert consensus document to provide important guidance on its use.

1 Feb 2012

Nearly one in four women have another surgery following partial mastectomy

Nearly one in four women who undergo a partial mastectomy for treatment of breast cancer have another surgery to remove additional tissue (reexcision), and there is substantial surgeon and institutional variation in the rate of reexcisions that cannot be explained by patients' clinical characteristics, according to a study in the February 1 issue of JAMA.

1 Feb 2012

Potential way to block second wave of death from pneumonia treatment

An international research team may have found a way to block a second wave of death that can result from pneumonia treatment.

1 Feb 2012

Crizotinib can treat ROS1-driven tumors

A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S.

1 Feb 2012

HSP40/70 linked to hepatitis C infection

Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks viral replication, which can lead to liver cancer and cirrhosis.

31 Jan 2012

ASI's GenASIs for detection of chromosomal aberrations in bladder cancer receives FDA approval

Applied Spectral Imaging (ASI) announced today that ASI's GenASIs Scan & Analysis, SpotScan used for the detection of chromosomal aberrations in bladder cancer has been cleared by the United States Food and Drug Administration (FDA) for marketing in the US.

30 Jan 2012

Leprosy pathogen exploits micro-RNAs to weaken immune response

A team of UCLA scientists has found that the pathogen that causes leprosy has a remarkable ability to avoid the human immune system by inhibiting the antimicrobial responses important to our defenses.

30 Jan 2012

Book launch marks anniversary of GABBA Program

On Monday 30th January at 6 p.m. in the Rectory of the University of Porto (Praça Gomes Teixeira), the Secretary of State for Science, Leonor Parreira and the ex-Minister for Science, Technology and Higher Education, Mariano Gago, will attend the commemoration ceremony for the 15th anniversary of the Graduate Program in Basic and Applied Biology (GABBA) at the University of Porto.

30 Jan 2012

Pinpoint Genomics makes Pinpoint Dx Lung Assay available to clinicians, patients

Pinpoint Genomics, Inc. announced the publication of key data relating to its Pinpoint Dx Lung Assay in the journal The Lancet, and the availability of its Pinpoint Dx Lung Assay to clinicians and patients exclusively through the company's laboratory in Mountain View, CA.

30 Jan 2012

Researchers develop new MRS technique to diagnose brain tumors

Researchers at UT Southwestern Medical Center have developed what they believe to be the first clinical application of a new imaging technique to diagnose brain tumors.

30 Jan 2012

Susan Mallery finds breakthrough treatment for oral cancer

Dr. Susan Mallery, a professor in the College of Dentistry at The Ohio State University and Oral Pathology Consultant at the Ohio State University and James Cancer hospitals, has dedicated her nearly 30-year career to studying new strategies to preventing oral cancer.

30 Jan 2012

Reason for language development delay in boys – Testosterone: Study

For the new study researchers collected umbilical cord blood from 767 Australian newborns and tested for testosterone. Newborn boys are exposed to 10 times the levels of testosterone before birth, compared to girls. Sex hormones, like testosterone, are known to play a key role in shaping how the brain develops. Then, the researchers evaluated the children’s language skills when they were 1, 2 and 3 years of age.

29 Jan 2012

Researchers identify possible cause for loss of tumor suppressor genes

Researchers at Queen's University in Kingston, Canada have identified a possible cause for the loss of a tumour suppressor gene (known as PTEN) that can lead to the development of more aggressive forms of prostate cancer.

27 Jan 2012

GenPath, BioReference Labs to introduce OnkoMatch solid tumor genotype test

BioReference Laboratories, Inc. and its GenPath Oncology business unit and through its exclusive commercialization agreement with the Massachusetts General Hospital (MGH) is introducing its groundbreaking solid tumor genotype test.

27 Jan 2012

Scientists connect two signature characteristics of pancreatic cancer

Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms of cancer.

27 Jan 2012

Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

New links between leukemia cells and osteoblasts

University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia.

27 Jan 2012

Breakthroughs in Alzheimer’s disease research

Researchers are closer to understanding Alzheimer’s disease using a new stem cell technique. They have successfully replicated Alzheimer’s disease neurons with stem cells for the first time.

26 Jan 2012

UCSF team develops methods that may help predict brain tumor recurrence

After people with low-grade glioma, a type of brain cancer, undergo neurosurgery to remove the tumors, they face variable odds of survival - depending largely on how rapidly the cancer recurs. Even though their doctors monitor the tumor closely with sophisticated imaging, it is difficult to determine with certainty whether cancer has returned in a more malignant state that requires aggressive treatment.

25 Jan 2012