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Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Researchers investigated the effectiveness of the SARS-CoV-2 Omicron-variant induced immunity, whether it is cross-protective against other variants, and if earlier infection with the SARS-CoV-2 Delta variant offers protection against Omicron.

20 Jan 2022

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

A new bioRxiv* preprint study led by Michelle Monje of Stanford University in California finds that a mild COVID-19 infection can produce long-term neurological damage. Persistent cognitive complications are one of many symptoms of long COVID, and the latest results suggest the severity of COVID-19 induced brain fog is similar to cancer’s “chemobrain.”

16 Jan 2022

Exploring why children have milder COVID-19 infections compared to adults

A new study has revealed that an activated pre-exposure innate interferon response in airways together with significantly reduced systemic interferon-stimulated populations are associated with relatively milder severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children.

23 Dec 2021

Distinct plasma proteins linked to presence and course of COVID-19

In a study published in Viruses, researchers have examined the difference in protein levels in COVID-19 patients.

10 Dec 2021

Lunaphore highlights novel spatial biology research at SITC 2021

Lunaphore today announced new research from collaborators at the University of Birmingham.

From Lunaphore 7 Dec 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

A recent study has demonstrated that SARS-CoV-2 infection induces a significantly lower interferon response than rhinovirus infection.

24 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

SARS-CoV-2 infection inhibited by CCR2 signaling

A new study discusses the role of monocytes in protecting individuals from SARS-CoV-2.

15 Nov 2021

Investigation of Budesonide's mechanism of action against SARS-CoV-2

Researchers look to gain an understanding of the mechanism of action of budesonide in improving the prognosis of patients with SARS-CoV-2 infection.

1 Nov 2021

Novel proteomics approach predicts severe COVID-19 outcomes

Researchers in the United States, Canada, and the UK have developed a potential new approach to predicting severe and critical outcomes among patients with coronavirus disease 2019 (COVID-19).

6 Oct 2021

The role of ZBP1 in promoting SARS-CoV-2-induced cytokine expression

A new study reported that the ZBP1-induced inflammatory signaling pathway is dependent on ubiquitination and RIPK3’s scaffolding ability, independent of cell death.

5 Oct 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

Scientists identify potential biomarkers to predict COVID-19 outcomes

A team of scientists from the United States has recently examined the trajectory of early immune biomarkers in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. They have identified specific plasma proteins that can accurately predict the clinical and virological outcomes in SARS-CoV-2 infected patients. The study is currently available on the medRxiv* preprint server.

31 Aug 2021

How early interferon curbs SARS-CoV-2 infection

A new study available in the Journal of Experimental Medicine focuses on the importance of interferon in SARS-CoV-2 infection.

30 Aug 2021

Study reveals effective strategy to extend the benefit of immunotherapy for prostate cancer

It's a scientific riddle tangled up in a complex web. How do you turn an immune cold cancer into one that responds to immunotherapy?

2 Aug 2021

Smoother silicone breast implants can reduce inflammation and other immune system reactions

According to researchers at Johns Hopkins Medicine, the Massachusetts Institute of Technology (MIT) and Rice University in Houston, silicone breast implants with a smoother surface design have less risk of producing inflammation and other immune system reactions than those with more roughly textured coatings.

22 Jun 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

The role of natural killer cells in fight against viral infections including SARS-CoV-2

In an effort to further understand the role of NK cells in combatting COVID-19, a group of researchers explored NK cells in acute viral infections, citing flavivirus and influenza virus infections as examples.

17 Jun 2021