Inflammasome News and Research

RSS

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Inflammasome protects stem cells from becoming cancerous

13 Jan 2025

Study explains how the body’s internal clock influences inflammatory process of the immune system

New research from RCSI University of Medicine and Health Sciences has explained how the body’s internal clock influences the inflammatory process of the immune system.

17 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024

Study points to a strategy for inhibiting hyper-progression of melanoma

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

25 Nov 2024

From womb to midlife: Prenatal immune disruptions reshape memory and cognitive aging

Prenatal exposure to maternal pro-inflammatory cytokines shapes memory and immune function in offspring, with sex-specific effects emerging over 50 years.

24 Nov 2024

$Herba Siegesbeckiae subfraction HS-C protects against myocardial I/R injury$

Herba Siegesbeckiae subfraction HS-C protects against myocardial I/R injury

Announcing a new publication for Acta Materia Medica journal. Herba Siegesbeckiae (HS) has been traditionally used for managing cardio- and cerebro-vascular diseases.

5 Nov 2024

New study reveals molecular mechanism in Alzheimer's disease

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients.

18 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke.

25 Sep 2024

Study links periodontal bacteria to worsening rheumatoid arthritis

Periodontal disease, which affects the gums and tissues that surround the teeth, is one of the most prevalent dental conditions worldwide.

5 Sep 2024

Ohio State leads multi-million dollar research on long COVID solutions

A 2022 study suggesting that blocking a single molecule could protect against severe illness in COVID-19 has led to a $15 million federal grant supporting a comprehensive effort to learn more – with finding a solution to long COVID at the center of the new research.

23 Jul 2024

St. Jude researchers uncover NLRC5's role in immune response and cell death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

14 Jun 2024

New diagnostic and treatment approach could revolutionize bladder cancer care

A new diagnostic and treatment approach for bladder cancer will undergo a clinical trial in Queensland.

6 May 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Discovering the on-switch for rare genetic inflammatory diseases

University of Queensland researchers have discovered how the 'on-switch' for the body's inflammation machinery can get stuck and cause rare genetic inflammatory diseases.

18 Mar 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Cambridge scientists discover how fasting turns up the body's natural inflammation fighter

Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation – a potentially damaging side-effect of the body's immune system that underlies a number of chronic diseases.

30 Jan 2024