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FairJourney Bio launches cryo-EM services with advanced laboratories in San Diego, USA

FairJourney Bio (FJBio), a leading global provider of antibody discovery and development services, today announced the expansion of its portfolio with the launch of state-of-the-art cryo-electron microscopy (cryo-EM) services, supported through the Company's advanced laboratories in San Diego, CA.

12 Jan 2026

Researchers develop enhanced antibodies to unleash the immune system against cancer

Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.

8 Jan 2026

New antibody mechanisms disrupt bacterial adhesion in urinary tract infections

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

7 Jan 2026

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.

7 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Repurposed drug combination shows strong promise against liver fibrosis

The study shows that this drug pair works far better together than either agent alone, offering a realistic and potentially fast path toward a new antifibrotic therapy.

6 Jan 2026

COVID-19 immunity stays specific and barely boosts protection against common cold coronaviruses

This study shows that SARS-CoV-2 infection and vaccination generate strong, highly specific spike-binding immune responses with only modest effects on immunity to endemic common cold coronaviruses. Pre-existing coronavirus immunity patterns remain largely intact, indicating that SARS-CoV-2 has integrated into the human viral landscape without broadly reshaping cross-reactive protection.

5 Jan 2026

Novel mRNA therapy rejuvenates immune function in aging mice

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.

17 Dec 2025

Circadian control of neutrophils limits heart damage after myocardial infarction

Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program. Activating a CXCL12–CXCR4 checkpoint repositions neutrophils, limiting inflammatory injury without impairing antimicrobial defense.

15 Dec 2025

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

13 Dec 2025

New findings show why the human intestine uniquely presents gluten to T cells

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity and specialized machinery for processing gluten. Their ability to deamidate and present gliadin peptides positions them as key initiators of immune responses relevant to coeliac disease.

11 Dec 2025

Why soybean oil may fuel weight gain

Researchers investigate how soybean oil may disrupt fat metabolism to potentially increase the risk of obesity.

4 Dec 2025

Researchers identify key differences between two subtypes of chronic lymphocytic leukemia

Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL.

18 Nov 2025

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with a five-year survival rate near 50%.

13 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Ligand News and Research

FairJourney Bio launches cryo-EM services with advanced laboratories in San Diego, USA

Researchers develop enhanced antibodies to unleash the immune system against cancer

New antibody mechanisms disrupt bacterial adhesion in urinary tract infections

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

TAAR1 mutation impairs brain signaling in schizophrenia

Repurposed drug combination shows strong promise against liver fibrosis

COVID-19 immunity stays specific and barely boosts protection against common cold coronaviruses

Novel mRNA therapy rejuvenates immune function in aging mice

Circadian control of neutrophils limits heart damage after myocardial infarction

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

New findings show why the human intestine uniquely presents gluten to T cells

Why soybean oil may fuel weight gain

Researchers identify key differences between two subtypes of chronic lymphocytic leukemia

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Integrating physicochemical laws into future AI models for better drug design

Novel computational platform can design synthetic protein receptors from scratch

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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