Nephrology News and Research

RSS

Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Suppression of cdc42 activity could be a promising therapy for nephrotic syndrome

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

6 Aug 2025

New blood markers predict kidney disease and mortality in diabetes

Kidney complications in diabetes often progress silently, putting patients at risk of life-threatening outcomes long before any symptoms appear. Identifying individuals with diabetes who are at risk of rapid kidney function decline or early death has challenged doctors for decades, with traditional markers like serum creatinine and urinary albumin falling short of accurately predicting these risks.

29 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025

Assisted reproductive technology raises pregnancy risks in women with kidney transplants

Women with kidney transplants who use assisted reproductive technology (ART) to conceive might face higher risks of complications during pregnancy, according to new research from the University of Cincinnati College of Medicine.

7 Jul 2025

Study reveals persistent inequalities in children's access to kidney transplants across the UK

New research, presented at the ESOT Congress 2025, reveals persistent inequalities in children's access to life-saving kidney transplants across the UK.

1 Jul 2025

Autoantibodies against vinculin linked to childhood kidney disease

19 Jun 2025

Vaccination linked to better kidney outcomes in hospitalized COVID-19 patients

Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests.

14 Jun 2025

Study: Deceased-donor kidney transplants do not benefit all patients equally

A major international study, being presented today at the 62nd ERA Congress, reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

New biomarker identified for predicting microvascular health of the kidneys

In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

27 May 2025

TMEM219 inhibition shows promise in restoring intestinal health in IBD

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases.

15 May 2025

Multidimensional sleep health linked to better cardiometabolic outcomes

Healthy sleep includes multiple components, such as number of hours of sleep per night, how long it takes to fall asleep, daytime functioning and self-reported sleep satisfaction, and addressing these different dimensions of sleep may help to reduce cardiometabolic health and related risk factors, according to a new American Heart Association scientific statement published today in Circulation: Cardiovascular Quality and Outcomes.

14 Apr 2025

Six promising biomarkers could improve early and accurate detection of kidney injury

Critical Path Institute® (C-Path) and Boston Medical Center (BMC) published results for six biomarkers that could improve the early and accurate detection of kidney injury, leading to both the development of safer medications and better health outcomes for all patients.

28 Mar 2025

High blood pressure can lead to structural changes in the kidneys

A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes.

27 Mar 2025

Conversations on AFM: Exploring the nanomechanics of living cells

In this interview Prof. Dr. Kristina Kusche-Vihrog speaks about the nanomechanics of living cells and their implications for cardiovascular disease.

From Bruker BioAFM 27 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

How to bridge the historical divide between physical and mental wellness

In a comprehensive Genomic Press Interview published today in Brain Medicine, psychiatry resident Dr. Nicholas Fabiano reveals how a personal injury transformed into groundbreaking research on the intersection of physical and mental health.

4 Mar 2025

Doctors speaking the patient's language linked to lower cardiovascular disease risk

A positive patient-doctor relationship is an ingredient to a healthy life, and new research has zeroed in on the impact common language in the relationship can have by decreasing cardiovascular disease for the benefit of a longer life.

21 Feb 2025

Innovative method improves understanding of cellular and molecular mechanisms in kidney diseases

Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic kidney disease (CKD), at both the cellular and molecular levels.

19 Feb 2025