Nitric Oxide News and Research

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Sitting harms blood vessel function, but cocoa flavanols can stop it

This study shows that cocoa flavanols can preserve endothelial function during sitting, suggesting dietary strategies to mitigate cardiovascular risks.

17 Dec 2025

External signals control oncolytic bacteria for precise cancer therapy delivery

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.

13 Dec 2025

Glycation stress drives aortic stiffening through oxidative stress and senescence

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled "Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence."

12 Dec 2025

Bedfont® Scientific Limited expands global access to FeNO testing in India

Bedfont® Scientific Limited, world leaders in breath analysis, with over 48 years of experience in designing and manufacturing medical breath analysis devices, has collaborated with Rbeck Healtech Private to make Fractional exhaled Nitric Oxide (FeNO) testing more accessible in India.

From NObreath 1 Dec 2025

Evidence links severe gum disease to erectile dysfunction and broader men’s health risks

A healthy mouth is also key to a healthy body, as gum disease has been linked to non-communicable diseases such as diabetes, cardiovascular disease, rheumatoid arthritis and Alzheimer's.

20 Nov 2025

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Pertussis, or whooping cough, remains a highly contagious respiratory infection caused by Bordetella pertussis. Despite inclusion of pertussis vaccines in immunization programs since the 1970s, outbreaks have re-emerged globally due to waning immunity and bacterial evolution.

19 Nov 2025

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Heated tobacco and cigarettes cause the same gut and vascular damage, study finds

Italian researchers found that both heated tobacco products (HTPs) and conventional cigarettes trigger oxidative stress, endotoxemia, and gut barrier disruption in adults and children. The findings challenge the perception that HTPs are a safer alternative to smoking.

3 Nov 2025

Hydroxytyrosol from olives shows new promise as a brain-protective compound

This review highlights hydroxytyrosol's role as a neuroprotective agent, activating key pathways for mental and vascular health through olive-derived compounds.

29 Oct 2025

Study finds small but significant sprint gains from dark chocolate milk intake

A new study found that consuming dark chocolate milk before exercise modestly enhanced anaerobic sprint performance in healthy young adults. The gains, seen in total effort time and power output, were small but potentially meaningful for competitive athletes.

23 Oct 2025

Does eating watermelon lower blood pressure?

Researchers reviewed the role of watermelon as a natural source of L-citrulline and its potential to improve cardiovascular health by enhancing nitric oxide production. While promising effects on blood pressure and arterial stiffness were seen in at-risk groups, long-term and dose-specific studies are still needed to confirm clinical benefits.

15 Oct 2025

Discovery of CPD gene mutations sheds light on rare congenital hearing loss

Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing loss, an international team of researchers has discovered.

14 Oct 2025

Engineered antibody triggers powerful anti-tumor response in advanced cancers

Many advanced cancers develop resistance to treatment and become highly aggressive, often leaving patients with limited treatment options.

13 Oct 2025

Rising temperatures put older hearts in danger

Research reveals aging hearts struggle with extreme heat, increasing cardiovascular risks for older adults as climate change intensifies global temperatures.

7 Oct 2025

Exercise beats yoga for improving heart and blood vessel health

Researchers compare the effects of physical exercise and yoga on cardiovascular function.

7 Oct 2025

Lysosomal acidity fine-tunes reactive species production in macrophages

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis.

21 Sep 2025

How processed red meat might drive neurodegenerative diseases

The relationship between processed red meat and neurodegenerative diseases is complex, with potential risks and protective effects requiring more investigation.

15 Sep 2025

Review highlights immunomodulatory and therapeutic effects of ginseng

Ginseng has long been used in traditional medicine to replenish Qi and address deficiency syndromes, often manifesting as fatigue and immune compromise.

13 Sep 2025

Bedfont® to showcase the innovative Smokerlyzer® and NObreath® respiratory devices at ERS 2025

Bedfont® Scientific Limited, an innovative med-tech company with over 48 years of knowledge and expertise in the manufacture of medical breath analysis devices, are seeking new strategic distribution partners at this year's European Respiratory Society (ERS) Congress.

From Bedfont® Scientific Ltd 9 Sep 2025

Beetroot juice lowers blood pressure in older adults by reshaping oral bacteria

Dietary nitrate from beetroot juice lowered blood pressure in older adults but not in younger participants in a double-blind crossover trial. The effect was linked to oral microbiome changes, including reduced Prevotella and higher plasma nitrite, without improvements in endothelial function

2 Sep 2025