Ovaries News and Research

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Researchers uncover how chromosome crossovers protect fertility

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

24 Sep 2025

Loss of Trp53 gene affects immune responses in ovarian cancer

A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled "Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma."

24 Sep 2025

Study identifies immune biomarkers for personalized therapies in pediatric germ cell tumors

A study conducted by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos (formerly Barretos Cancer Hospital) in the state of São Paulo, Brazil, has identified possible biomarkers that could guide the development of more personalized therapies for pediatric germ cell tumors (GCTs).

18 Sep 2025

CoQ10 shows promise in boosting female fertility by reviving aging eggs

Researchers reviewed evidence on Coenzyme Q10 (CoQ10) and found it may enhance mitochondrial function, improve oocyte quality, and counteract age-related fertility decline. The review highlights promising results from clinical, preclinical, and in vitro studies but calls for larger trials to confirm safety, dosing, and effectiveness.

16 Sep 2025

Adjusting fertility drug timing boosts ovulation success in rat models

Researchers at Osaka Metropolitan University have found that changing the timing of fertility drugs to match the follicle maturity period significantly increases the number of ovulated oocytes-the cells that develop into eggs-during artificial fertilization, even in rats that typically produce few oocytes.

27 Aug 2025

First comprehensive road map shows how the ovarian reserve forms in primates

UCLA scientists have developed the first comprehensive road map showing how the ovarian reserve forms in primates, providing crucial insights into women's health that could revolutionize treatments for infertility and hormonal disorders such as polycystic ovary syndrome, or PCOS.

26 Aug 2025

Study finds link between epigenetic aging and colorectal cancer risk in postmenopausal women

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 7, 2025, titled "Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer."

19 Aug 2025

Diagnostic mimicry and management of rare pure form of ovarian cancer

A new case report was published in Volume 12 of Oncoscience on July 28, 2025, titled "A rare case of pure non-gestational ovarian choriocarcinoma: Diagnostic mimicry and management strategies."

14 Aug 2025

New insights into depressive symptoms in premature ovarian insufficiency

Premature menopause has been described as a life-changing diagnosis with profound physical, psychological, and social consequences. Affected women not only experience the effects of estrogen deficiency, but they also experience the unanticipated loss of reproductive function.

16 Jul 2025

Night shift work linked to irregular periods and hormonal imbalances

Women who work night shifts may have an increased risk for irregular periods and hormonal imbalances, according to a study being presented Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

14 Jul 2025

Study: Obesity-linked cancer deaths have tripled in the United States

Cancer deaths linked to obesity have tripled in the United States over the past two decades, according to a study being presented Sunday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

13 Jul 2025

PCOS patients often feel dismissed, misunderstood and underserved by the healthcare system

A new study from the University of Colorado Anschutz Medical Campus reveals that individuals living with Polycystic Ovary Syndrome (PCOS) often feel dismissed, misunderstood and underserved by the healthcare system.

7 Jul 2025

New combination therapy inhibits tumor growth and blocks drug-induced resistance in ovarian cancer

A pairing of two experimental drugs inhibits tumor growth and blocks drug-induced resistance in ovarian cancer, according to a preclinical study led by Weill Cornell Medicine investigators.

7 Jul 2025

Embryos from women with PCOS carry distinctive epigenetic memory

Novel research presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) has found that embryos from women with polycystic ovary syndrome (PCOS) carry a distinctive 'epigenetic memory' that could explain why the condition often runs in families.

1 Jul 2025

Study links hormone therapy to breast cancer risk in younger women

Scientists at the National Institutes of Health (NIH) have found that two common types of hormone therapy may alter breast cancer risk in women before age 55.

1 Jul 2025

Mayo Clinic researchers discover how ovarian cancer may begin

Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.

24 Jun 2025

Caloric restriction may help delay decline in reproductive function associated with aging

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 20, 2025, titled "Short-term moderate caloric restriction in the rhesus macaque attenuates markers of ovarian aging in select populations."

24 Jun 2025

Low FODMAP diet shown to improve gastrointestinal symptoms in women with endometriosis

A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.

23 Jun 2025

BRCA mutations sharply increase risk of implant-associated lymphoma

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely to develop breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare T-cell lymphoma, compared with similar women without these genetic mutations, according to a study published today in Blood Advances.

14 Jun 2025

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled "A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation."

13 Jun 2025