Ovaries News and Research

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Embryos from women with PCOS carry distinctive epigenetic memory

Novel research presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) has found that embryos from women with polycystic ovary syndrome (PCOS) carry a distinctive 'epigenetic memory' that could explain why the condition often runs in families.

1 Jul 2025

Study links hormone therapy to breast cancer risk in younger women

Scientists at the National Institutes of Health (NIH) have found that two common types of hormone therapy may alter breast cancer risk in women before age 55.

1 Jul 2025

Mayo Clinic researchers discover how ovarian cancer may begin

Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.

24 Jun 2025

Caloric restriction may help delay decline in reproductive function associated with aging

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 20, 2025, titled "Short-term moderate caloric restriction in the rhesus macaque attenuates markers of ovarian aging in select populations."

24 Jun 2025

Low FODMAP diet shown to improve gastrointestinal symptoms in women with endometriosis

A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.

23 Jun 2025

BRCA mutations sharply increase risk of implant-associated lymphoma

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely to develop breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare T-cell lymphoma, compared with similar women without these genetic mutations, according to a study published today in Blood Advances.

14 Jun 2025

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled "A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation."

13 Jun 2025

Difficult childhood experiences linked to increased risk of endometriosis later in life

A new study from Karolinska Institutet involving over a million women links difficult childhood experiences to the risk of being diagnosed with endometriosis later in life.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer

A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer – and offers a potential pathway for new treatments.

9 Jun 2025

Discovery unravels two populations of gonadotrophs in the pituitary gland

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought.

21 May 2025

Lipid overload in ascites weakens immune response in ovarian cancer

A Ludwig Cancer Research study has identified a key mechanism by which advanced ovarian cancers suppress anti-tumor immune responses and resist immunotherapies.

13 May 2025

Simple oral swab test could revolutionize IVF success rates

About 15 per cent of all couples of reproductive age are involuntarily childless. A major reason why so many need assisted reproduction is that nowadays more and more people are putting off starting a family.

13 May 2025

Testosterone use not linked to increased gynecological cancer risk in early years

Transmasculine and gender-diverse individuals who use testosterone are not at increased risk of gynecological cancer in the first years of hormone therapy.

12 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Maternal testosterone levels shape boys' activity and girls' strength by age 7

Boys born to mothers with PCOS or high third-trimester testosterone levels are less physically active at age 7, particularly on weekends. Girls exposed to high prenatal testosterone show reduced muscle strength but not lower activity levels.

10 May 2025

Ovary and fallopian tube removal linked to lower death risk in BRCA carriers with breast cancer

Women diagnosed with breast cancer who carry particular BRCA1 and BRCA2 genetic variants are offered surgery to remove the ovaries and fallopian tubes as this dramatically reduces their risk of ovarian cancer.

8 May 2025

New molecule offers hope for chlamydia treatment

Researchers at Umeå University, Sweden, and Michigan State University, USA, have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health.

8 May 2025

Study shows brain estrogen directly regulates appetite in mice

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed that neuroestrogen boosts leptin sensitivity, suggesting new targets for obesity treatment.

2 May 2025

Endometriosis raises the risk of premature menopause in women

Women who suffer from endometriosis have an increased risk of premature and early menopause, both naturally and surgically, University of Queensland researchers have found.

30 Apr 2025