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Study: Empagliflozin shows mixed results in heart attack patients

Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Interatrial shunt may offer differential benefits based on heart failure type

Patients with heart failure who had a small shunt inserted between the heart's left and right atria did not see any significant benefits overall compared with those who received a placebo procedure after a median of 22 months follow-up, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

In patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran reduced triglyceride levels by an average of 74% after 24 weeks of use without causing any significant safety concerns, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Study questions routine use of beta blockers after heart attack

Taking beta blockers after a heart attack did not significantly reduce the risk of death or a second heart attack among people with normal heart pumping ability, as indicated by an ejection fraction of 50% or higher, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Study shows promise of zilebesiran injection in reducing systolic blood pressure

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure by between 4 to 12 mmHg on average at three months in patients whose blood pressure had remained uncontrolled despite compliance with their medication regimen, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Blood-based DNA test spares bladder cancer patients from unnecessary treatments

Testing for tumor DNA in the blood can successfully identify advanced bladder cancer patients who will not relapse following surgery, new research shows.

4 Apr 2024

Unlocking role of the cerebellum in reward-based learning

If you reward a monkey with some juice, it will learn which hand to move in response to a specific visual cue – but only if the cerebellum is functioning properly.

4 Apr 2024

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Study reviews the advancements in pharmacological treatments for neuropsychiatric syndromes in neurodegenerative disorders, discussing the complexities of managing symptoms such as depression, disinhibition, apathy, psychosis, and agitation to improve patient care.

3 Apr 2024

Statins slightly up diabetes risk but cardiovascular benefits remain, finds study

Statin therapy modestly increases diabetes diagnoses but offers substantial cardiovascular benefits, outweighing the slight rise in glycemia, especially in those near diabetes diagnostic thresholds.

2 Apr 2024

Stem cell therapy safe and potentially beneficial for spinal cord injury patients

A Mayo Clinic study shows stem cells derived from patients' own fat are safe and may improve sensation and movement after traumatic spinal cord injuries.

1 Apr 2024

Statins linked to slight diabetes risk but benefits outweigh the concerns

Statin use is associated with a moderate, dose-dependent increase in the risk of new-onset diabetes, particularly in individuals close to the diabetes threshold, yet the cardiovascular benefits of statin therapy remain substantial.

28 Mar 2024

ADHD medication proves most effective in treating symptoms, new study finds

A comprehensive overview of treatment options available for ADHD for children and adolescent individuals.

27 Mar 2024

No consistent pattern found in health responses to blueberry interventions, study shows

A blueberry intervention using quartile divisions to define inter-individual responses in vascular and cognitive endpoints.

22 Mar 2024

Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

The metabolic implications of iodine consumption and elucidated the underlying mechanisms.

21 Mar 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Mouse models shed light on the effects of metformin use during pregnancy on offspring

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently.

18 Mar 2024

Apple cider vinegar shows promise for weight management in overweight and obese individuals

Small daily quantities of apple cider vinegar for 12 weeks aid weight management in people who are overweight or obese, suggest the results of a small comparative clinical trial, published in the open access journal BMJ Nutrition, Prevention & Health.

18 Mar 2024

Vitamin D supplementation shows limited benefits for bone and heart health in hypertensive patients

Study evaluates the impact of vitamin D supplementation on bone health and cardiovascular risk factors in hypertensive patients, finding no significant improvements except in PTH levels, highlighting the complexity of vitamin D metabolism.

17 Mar 2024

Researchers find link between gut bacteria and the success of milk-allergy oral immunotherapy

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences in Japan have discovered a link between gut bacteria and the success of milk-allergy oral immunotherapy.

14 Mar 2024

Placebo News and Research

Study: Empagliflozin shows mixed results in heart attack patients

Interatrial shunt may offer differential benefits based on heart failure type

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study questions routine use of beta blockers after heart attack

Study shows promise of zilebesiran injection in reducing systolic blood pressure

Blood-based DNA test spares bladder cancer patients from unnecessary treatments

Unlocking role of the cerebellum in reward-based learning

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Statins slightly up diabetes risk but cardiovascular benefits remain, finds study

Stem cell therapy safe and potentially beneficial for spinal cord injury patients

Statins linked to slight diabetes risk but benefits outweigh the concerns

ADHD medication proves most effective in treating symptoms, new study finds

No consistent pattern found in health responses to blueberry interventions, study shows

Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

Mouse models shed light on the effects of metformin use during pregnancy on offspring

Apple cider vinegar shows promise for weight management in overweight and obese individuals

Vitamin D supplementation shows limited benefits for bone and heart health in hypertensive patients

Researchers find link between gut bacteria and the success of milk-allergy oral immunotherapy

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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