Prophylaxis News and Research

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Llama-derived nanobody VHH21 destroys the spike-trimer of SARS-CoV-2

Neutralizing antibodies that merely block receptor binding are losing ground against heavily mutated SARS-CoV-2 Omicron sub-variants.

14 Aug 2025

Inside the CDC, shooting adds to trauma as workers describe projects, careers in limbo

Centers for Disease Control and Prevention workers whose jobs have been reinstated after dizzying Trump administration disruptions say they remain stuck in a budgetary, political, and professional limbo.

11 Aug 2025

Personalizing endometrial cancer prevention through diet and lifestyle

This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.

7 Aug 2025

A tourist ended up with a wild bat in her mouth — and nearly $21,000 in medical bills

In retrospect, Erica Kahn realizes she made two big mistakes. The first was choosing to temporarily forgo health insurance when she was laid off from her job.

31 Jul 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Study highlights gaps in preeclampsia risk assessment and aspirin use

A new study sponsored by Mirvie, which is the first to evaluate U.S. Preventive Services Task Force (USPSTF) guidelines for preeclampsia risk and aspirin prescription in a single, nationally representative, prospective population, found while high-risk factors had sufficient value in estimating risk, there's limited value for the moderate risk category - leading to nonspecific recommendations for aspirin use, a recognized prevention tool.

18 Jul 2025

Challenges in identifying high risk patients for preeclampsia using USPSTF guidelines

Preeclampsia (PE) is a hypertensive disease that complicates 7-10% of pregnancies. While recent advances in understanding the underlying causes of PE have been made, predicting its occurrence has historically been difficult because it is a complex condition that likely results from a variety of causes and can present in different ways.

17 Jul 2025

Many HIV-exposed newborns miss preventive treatment after birth

Newborns exposed to HIV during pregnancy or birth should receive preventive antiretroviral medication immediately after delivery to reduce the risk of transmission from mother to child.

16 Jul 2025

New WHO guidelines recommend injectable lenacapavir for HIV prevention

The World Health Organization (WHO) released today new guidelines recommending the use of injectable lenacapavir (LEN) twice a year as an additional pre-exposure prophylaxis (PrEP) option for HIV prevention, in a landmark policy action that could help reshape the global HIV response.

14 Jul 2025

Research highlights an increase in informal use of doxyPEP/PrEP among key populations in the Netherlands

New research analyzing an online survey of 1,633 respondents found 15% recent use of doxycycline post- and pre-exposure prophylaxis (doxyPEP/PrEP) among men who have sex with men (MSM), transgender and gender diverse people in the Netherlands according to a recent study published by Eurosurveillance.

4 Jul 2025

Twice-yearly injection could transform HIV prevention efforts

Preventative therapies for HIV-1 (Human Immunodeficiency Virus type 1) have made leaps and bounds over the past decade. A once-daily pill named PrEP, or pre-exposure prophylaxis, has been a stalwart for HIV prevention-but only if people take it consistently and can routinely access a pharmacy.

3 Jul 2025

Partial match stem cell transplants show strong survival rates

Blood cancer patients who may have previously struggled to find a donor for transplantation now have more options.

26 Jun 2025

IL-6 and CRP offer limited boost for predicting infections after lung cancer surgery

Early postoperative levels of IL-6 and CRP are independently associated with infection risk after pulmonary cancer surgery. However, adding these biomarkers to standard clinical predictors provides only limited improvement in infection prediction.

25 Jun 2025

New RSV guideline aims to standardize pediatric care across China

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infections (ALRTIs) in children under five and poses a persistent threat to child health worldwide.

20 Jun 2025

New insights into gout management strategies and cardiovascular outcomes

The European Alliance of Associations for Rheumatology - recommends that serum urate should be maintained at <6 mg/dL (360 µmol/L) and <5 mg/dL (300 µmol/L) in those with severe gout.

15 Jun 2025

Study finds sharp rise in HIV prevention medication use among American youth

Eight times more American young adults now take medication to protect them from HIV than a decade ago, a new study finds.

23 May 2025

Maternal RSV vaccine and nirsevimab sharply cut infant hospitalizations, new data show

Widespread use of maternal RSV vaccination and nirsevimab during the 2024–2025 U.S. RSV season led to a significant reduction in RSV-associated hospitalizations among infants aged 0–7 months. The largest benefits were seen in the youngest and most vulnerable infants, particularly during peak winter months.

20 May 2025

UArizona researchers uncover new way to ease postoperative pain in women

University of Arizona Health Sciences researchers identified a potential way to reduce female post-operative pain by inhibiting pituitary prolactin generated by pre-operative stress.

20 May 2025

Repeated antibiotics in preterm infants linked to long-term lung problems

Repeated perinatal antibiotic exposure in very low-birth-weight preterm infants was associated with impaired lung function and a higher risk of asthma at early school age. The findings underscore the need for cautious antibiotic use and targeted respiratory health strategies in this high-risk group.

18 May 2025

Older adults in sub-Saharan Africa face growing HIV epidemic

Prevention and treatment campaigns are not adequately targeting the particular needs of the 50+ years age group.

15 May 2025