Renin News and Research

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Renin, also known as angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.

Presidential advisory by the American Heart Association: connecting cardiovascular, kidney, and metabolic health

The interplay among chronic kidney disease, metabolic risk factors, and the cardiovascular system.

11 Oct 2023

Insomnia's toll on the heart: study highlights cardiovascular event risks

Researchers performed a meta-analysis to evaluate the incidence of cardiovascular (CV) events among individuals with insomnia.

26 Sep 2023

Is hemp the superfood vegetarians have been waiting for?

This recent study in the journal Nutrients delves into the nutritional power of hemp seeds, highlighting their potential as a rich source of proteins, essential fatty acids, and dietary fiber—particularly valuable for vegetarians. The paper also suggests that hemp could offer numerous health benefits, from antioxidant activity to potentially aiding in metabolic and cardiovascular diseases, paving the way for more focused research.

22 Sep 2023

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

The University of Kentucky's Vice President for Research and leading cardiovascular scientist is being recognized for her foundational work in the field of hypertension with a prestigious award from the American Heart Association (AHA).

12 Sep 2023

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Researchers investigated the complexity of polypharmacy and whether frequent dose adjustments were required for co-medications and drug pairs in hospital settings.

7 Sep 2023

Is drinking water hardness associated with cardiovascular disease mortality?

Total drinking water hardness can protect against cardiovascular disease mortality.

30 Aug 2023

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

28 Aug 2023

Kidney–Gut axis: study shows potential link between gut dysbiosis and chronic kidney disease

Researchers reviewed published scientific work on the kidney-gut axis.

22 Aug 2023

Could plant-based diets help treat cardiovascular diseases?

In a recent article published in Nutrients, researchers identified a knowledge gap about the molecular mechanisms by which plant-based diets target cardiovascular diseases (CVDs).

22 Aug 2023

The impact of oat consumption on the gut microbiota

The relationship between the gut microbiome and oat consumption.

15 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

Study finds impaired beta cell function associated with severe COVID-19-induced hyperglycemia

A recent study aimed to investigate whether hyperglycemia persisted in COVID-19 survivors during a six-month follow-up.

19 Jul 2023

Vitamin D supplementation reduces risk of major cardiovascular events in older adults

Research investigates the impact of vitamin D supplementation on the incidence of major cardiovascular events in older adults. It examines whether monthly doses of vitamin D can alter the occurrence of heart-related problems.

4 Jul 2023

The link between Covid-19 and Alzheimer's disease established

Renin-angiotensin system, or RAS, is a physiological mechanism essential to human body function. The SARS-CoV-2 virus causes overactivation and malfunction of this system.

21 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Mutated gene protects the kidney from hypertension-induced damage

A mutation that causes severe hypertension also protects the kidneys from being damaged, reports a team led by Enno Klußmann of the Max Delbrück Center and the DZHK in "Kidney International".

30 May 2023

New review unravels phthalates’ role in heart disease

Researchers review existing data on the impact of phthalate exposure on cardiovascular health.

25 May 2023

Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations

The first investigator-initiated study of remote pulmonary artery pressure monitoring has found that it improves quality of life and reduces heart failure hospitalizations in patients with chronic heart failure.

22 May 2023

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Despite the success of vaccines for preventing COVID-19, and of drugs for treating the disease, outcomes for severely ill patients admitted to the hospital remains poor.

11 Apr 2023