Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.

22 Oct 2025

Research reveals how immune cells orchestrate the release of toxic granules

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules – microscopic packages that destroy virus-infected or cancerous cells.

17 Oct 2025

Global cancer cases and deaths expected to soar by 2050 despite advances in treatment

There has been a rapid increase in the global number of cancer cases and deaths between 1990 and 2023, despite advances in cancer treatment and efforts to tackle cancer risk factors over that same time period.

24 Sep 2025

Population aging identified as largest contributor to the increasing burden of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

16 Sep 2025

UC researcher wins $300,000 grant to investigate the underlying causes of eosinophilic esophagitis

Patients with eosinophilic esophagitis (EoE) often describe the condition as painful, disruptive and frightening.

11 Sep 2025

New guidelines for managing interstitial lung disease associated with connective tissue diseases

EULAR - The European Alliance of Associations for Rheumatology - has worked with the European Respiratory Society (ERS) to develop new clinical practice guidelines for interstitial lung disease (ILD) associated with connective tissue diseases (CTD).

5 Sep 2025

PEPITEM shows promise in treating osteoporosis by enhancing bone health

Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in PEPITEM molecule, and demonstrated the biological of activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.

2 Sep 2025

Gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

1 Sep 2025

New core dataset advances standardized care and research in systemic lupus erythematosus

The European Alliance of Associations for Rheumatology - has published new recommendations on core datasets to be used in systemic lupus erythematosus (SLE).

22 Aug 2025

Johns Hopkins team develops a more reliable AI for early cancer detection

Two studies led by Johns Hopkins Kimmel Cancer Center, Ludwig Center, and Johns Hopkins Whiting School of Engineering researchers report on a powerful new method that significantly improves the reliability and accuracy of artificial intelligence (AI) for many applications. As an example, they apply the new method to early cancer detection from blood samples, known as liquid biopsy.

19 Aug 2025

Mayo Clinic identifies cellular 'fountain of youth' in aging immune systems

The immune system is meant to protect the body from infection and disease. But with age, it can become less capable of doing so.

14 Aug 2025

‘A fear pandemic’: Immigration raids push patients into telehealth

Jacob Sweidan has seen his patients through the federal immigration raids of the 1990s, a sitting governor's call to abolish birthright citizenship, and the highly publicized workplace crackdowns and family separation policies of President Donald Trump's first term.

14 Aug 2025

New research explores foot positioning to treat knee osteoarthritis

Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an uncurable disease in which the cartilage cushion inside a joint breaks down.

13 Aug 2025

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

12 Aug 2025

Australian study finds lasting relief for back pain through cognitive functional therapy

Australian research has shown that a personalized program that helps people with chronic, disabling low back pain better understand their condition and take charge of its management produces large benefits that are sustained over three years.

5 Aug 2025

Early immunotherapy shows promise for treating anti-IgLON5 disease

Researchers ask physicians to consider anti-IgLON5 disease if certain symptoms are present, as the only promising approach is early treatment.

5 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Spinning's positive impact on hip osteoarthritis uncovered

A new study by Bournemouth University (BU) and University Hospitals Dorset (UHD) has revealed the benefits of spinning for patients with hip osteoarthritis. The study was funded by the National Institute for Health Research (NIHR) and will be published in Lancet Rheumatology at 23:30 UK time on Thursday 31st July 2025.

1 Aug 2025

New research links age-related gene changes to symptom decline

UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.

29 Jul 2025

Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025