Sarcoma News and Research

RSS

Study provides new insights into the genetic underpinnings of pediatric cancers

Largescale changes in the genome inherited from parents are significant risk factors for pediatric solid tumors, such as Ewing sarcoma, neuroblastoma, and osteosarcoma, according to a new study.

2 Jan 2025

Scientists create blood test to enhance cancer treatment effectiveness

Scientists from RMIT University and the Doherty Institute have developed a new blood test that could screen cancer patients to help make their treatment safer and more effective.

16 Dec 2024

Soft tissue sarcoma rates vary between active-duty military servicemen and general population

A recent analysis reveals that the incidence rates of soft tissue sarcomas - cancers in muscle, fat, blood vessels, nerves, and tendons - are lower in young U.S. active-duty military servicemen compared with those in the general population, but higher in middle-aged servicemen, perhaps due to greater cumulative exposure to toxins.

9 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

STAG2 loss linked to increased aggression in Ewing sarcoma

Ewing sarcoma is a tumor of the bones and soft tissues that occurs in children and young people. Like all childhood cancers, it is rare – 9 to 10 cases per million inhabitants per year – but it is very aggressive. 25% of patients do not respond well to regular therapy and they often experience relapses.

29 Nov 2024

UQ researchers move closer to developing topical cream for skin cancers in transplant patients

A topical cream to help prevent and treat skin cancers in organ transplant patients is a step closer to development.

28 Nov 2024

Common heart failure drug reduces risk of chemotherapy-induced heart damage in cancer patients

A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines, according to preliminary late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

CAR T cell therapy breakthroughs bring new hope for treating solid tumors

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor environments, with promising clinical results.

13 Nov 2024

New discovery reveals how mutant RAS genes drive tumor growth

Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling at the cell surface.

11 Nov 2024

Multi-omics-based classification of gastrointestinal stromal tumors lays groundwork for precision treatment

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these tumors.

5 Nov 2024

PIONEER software breaks down barriers in protein-protein interaction research

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication.

24 Oct 2024

Scientists map the genetic landscape of drug resistance in cancers

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective second-line therapies.

18 Oct 2024

Diagnostic performance of GPT-4 in analyzing radiology findings from brain tumors

GPT-4 demonstrates diagnostic capabilities in brain radiology, achieving 73% accuracy for final diagnoses and 94% for differential diagnoses in recent research.

3 Oct 2024

UCLA Health researchers showcase advances in radiation oncology at ASTRO

UCLA Health Jonsson Comprehensive Cancer Center researchers and physicians who specialize in treating patients with radiation therapies will present data on the latest radiation oncology research and clinical trial results at the 66th annual American Society for Radiation Oncology (ASTRO) meeting in Washington D.C., Sept. 29 to Oct. 2.

27 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

UCLA develops largest collection of patient-derived organoids for sarcoma research

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.

20 Sep 2024

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide.

18 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

EZH2's role in cancer progression and therapy explored

Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of the Polycomb-repressive complex 2 (PRC2), which plays a crucial role in transcriptional repression through the methylation of histone H3 on lysine 27 (H3K27me3).

9 Aug 2024