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New study reveals silent onset of rheumatoid arthritis

Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier.

24 Sep 2025

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.

24 Sep 2025

HIV protein Tat found to increase vulnerability to tuberculosis

According to the World Health Organization, tuberculosis accounts for one in three deaths among people living with HIV.

18 Sep 2025

Review highlights immunomodulatory and therapeutic effects of ginseng

Ginseng has long been used in traditional medicine to replenish Qi and address deficiency syndromes, often manifesting as fatigue and immune compromise.

13 Sep 2025

Electrical stimulation reprograms macrophages to reduce inflammation

Scientists from Trinity College Dublin have discovered that electrically stimulating "macrophages" – one of the immune systems key players – can "reprogramme" them in such a way to reduce inflammation and encourage faster, more effective healing in disease and injury.

2 Sep 2025

Impaired blood flow alters immunity and fuels tumor progression

Cutting off blood flow can prematurely age the bone marrow, weakening the immune system's ability to fight cancer, according to a new study from NYU Langone Health.

19 Aug 2025

Stem-like peripheral helper T cells found to sustain inflammation in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives.

17 Aug 2025

Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients

For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease.

7 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Study uncovers inflammatory pathways that contribute to asthma flare-ups in children

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

1 Aug 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Myeloid cells play central role in immune response after polytrauma

Gaining insights into the complex pathways and key cell populations involved in immune dysregulation can aid the development of therapeutic approaches to treat polytrauma, which is associated with poor patient outcomes.

21 Jul 2025

Boosting gut-friendly foods may slow biological aging, large US study finds

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

20 Jul 2025

New global guidelines aim to make clozapine safer and more accessible

The most effective antipsychotic drug for people with treatment-resistant schizophrenia is clozapine.

3 Jul 2025

Gene therapy brings back hearing in young and adult deaf patients

Gene therapy can improve hearing in children and adults with congenital deafness or severe hearing impairment, a new study involving researchers at Karolinska Institutet reports.

3 Jul 2025

Cannabis smoking changes your DNA, leaving epigenetic scars

Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic footprint on blood DNA. These methylation changes strongly overlap with those from tobacco and may serve as biomarkers of smoke exposure.

30 Jun 2025

IL-6 and CRP offer limited boost for predicting infections after lung cancer surgery

Early postoperative levels of IL-6 and CRP are independently associated with infection risk after pulmonary cancer surgery. However, adding these biomarkers to standard clinical predictors provides only limited improvement in infection prediction.

25 Jun 2025

First patient treated in international clinical trial for rare muscle-weakness disease

The first patient enrolled in a planned international clinical trial has been treated at HonorHealth Research Institute with a new type of immune therapy for those with a rare muscle-weakness disease known as Myasthenia Gravis.

16 Jun 2025

Biweekly chemotherapy dosing reduces toxicity in colorectal cancer patients

Patients with metastatic colorectal cancer who were treated with a biweekly dose of trifluridine-tipiracil (TAS-102) saw similar treatment effectiveness and reduced toxicity compared with treatment using standard dosing schedules, according to a recent study in The Oncologist that was co-authored by a Fox Chase Cancer Center physician.

6 Jun 2025

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members said. They didn't realize the drug could kill her.

4 Jun 2025