Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress.

2 Jul 2021

Study uncovers common neural mechanism for cognitive impairment in autism and schizophrenia

Many neurodevelopmental disorders share similar symptoms, such as learning disabilities or attention deficits.

30 Jun 2021

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Experts estimate more than 6 million Americans are living with Alzheimer's dementia. But a recent study, led by the University of Cincinnati, sheds new light on the disease and a highly debated new drug therapy.

28 Jun 2021

Virtual reality can help boost brain rhythms linked to learning and memory

A new discovery in rats shows that the brain responds differently in immersive virtual reality environments versus the real world.

28 Jun 2021

Study delves into the link between smoking and suicidal behaviors

Psychiatry and Clinical Psychology residents Iván Echeverria, Miriam Cotaina and Antonio Jovani, from the Hospital Provincial of Castellón, doctor Ana Benito and doctor Gonzalo Haro from the TXP research group of the CEU UCH, and doctor Rafael Mora, have published the results of their latest research: a meta-analysis on suicide, the first cause of external death in Spain.

25 Jun 2021

Hippocampal neurons fire during specific moments in time

Neurons in the hippocampus fire during specific moments in time, according to research recently published in JNeurosci. The cells may contribute to memory by encoding information about the time and order of events.

24 Jun 2021

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias?

21 Jun 2021

Study reveals the interplay between proteins that control the body's stress response

The biological mechanisms behind stress-related psychiatric conditions, including major depressive disorder and post-traumatic stress disorder (PTSD), are poorly understood.

21 Jun 2021

UIC discovery may lead to new treatments for alcohol use disorder and depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

14 Jun 2021

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function.

10 Jun 2021

Researchers map brain activity that flows when people learn a new skill

In a study of healthy volunteers, National Institutes of Health researchers have mapped out the brain activity that flows when we learn a new skill, such as playing a new song on the piano, and discovered why taking short breaks from practice is a key to learning.

9 Jun 2021

New study has implications for research and advancements in Alzheimer’s and related memory disorders

Scientists have observed for the first time what it looks like in the key memory region of the brain when a mistake is made during a memory trial.

9 Jun 2021

Researchers identify genomic cellular map associated with hippocampal sclerosis

A multidisciplinary team led by researchers from the Spanish Research Council identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy.

8 Jun 2021

Study offers a deeper understanding of the molecular basis for schizophrenia

A study conducted by a group of Brazilian researchers contributes to a deeper understanding of the molecular basis for schizophrenia, and potentially to the development of more specific and effective treatments for the disease.

8 Jun 2021

Pitt researchers use a unique and powerful MRI device to study sickle cell disease

Sickle Cell Disease (SCD) is a genetically inherited group of red blood cell disorders. According to the CDC, an estimated 90,000 to 100,000 people in the United States live with this disease, and it disproportionately affects Black or African Americans; it occurs in roughly 1 in every 500 individuals in this demographic.

3 Jun 2021

Research offers new hope for people affected by the microdeletion of chromosome 22

One person in 2000 suffers from a microdeletion of chromosome 22 that can lead to the development of psychotic disorders, such as schizophrenia, in adolescence.

1 Jun 2021

Study reveals a novel neuronal code for spatial perception

The brain is often likened to a computer: its hardware - neurons organized in complex circuits, its software - a plethora of codes that govern the neurons' behavior.

1 Jun 2021

Genomic study identifies marked differences between two halves of the hippocampus

A study of gene activity in the brain's hippocampus, led by UT Southwestern researchers, has identified marked differences between the region's anterior and posterior portions. The findings, published today in Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help lead to new, targeted treatments.

29 May 2021

Blood oxygen levels may explain why memory loss is an early symptom of Alzheimer's disease

In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.