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Altered protein and mutated clusters of genes in Alzheimer’s disease

Alzheimer's disease (AD) diagnosis and treatment has been a challenge and this is mainly due to the varying degrees of degeneration and cognitive damage seen in different patients. The researchers from the University of California San Diego School of Medicine for the first time used the transcriptome to assess the proteins made from the genes in patients with AD, that could help in diagnosis.

23 Jul 2019

Study finds factors associated with recovery among Indigenous people with suicidal thoughts

The higher prevalence of suicide among Indigenous peoples in Canada has been extensively documented, but little research has focused on factors associated with recovery among those who have had suicidal thoughts.

23 Jul 2019

Alzheimer's Association awards $3 million grant to support Longeveron's innovative clinical trial

The Alzheimer's Association has awarded Longeveron LLC, a Miami-based biopharmaceutical company that develops cellular therapies for aging-related diseases, a $3 million grant to be applied to the company's mesenchymal stem cell Alzheimer's research.

23 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Study finds striking differences in use of electronic health records among physicians

Modernizing health records by making them electronic has gained momentum as technology evolves and policies push health care toward digital solutions. But the same trend has not been evident for physicians who remain in private practice, new research finds.

22 Jul 2019

Aging nerve cells fail to take out the intracellular "trash"

Researchers at the Perelman School of Medicine at the University of Pennsylvania, have found that with age the neurons or nerve cells fail to perform an activity that they could when they were younger. The team explains that normal cells take out protein and other “trash” or “garbage” through a process of autophagy. This rids the cell of the dysfunctional proteins and aggregates of unused proteins.

22 Jul 2019

New book explains about the molecular mechanisms implicated in skeletal muscle aging

Sarcopenia, the progressive loss of muscle mass and associated muscle weakness during aging, affects the functional capacity and general health in adult people radically and renders frail elders susceptible to serious injury from sudden falls and fractures.

21 Jul 2019

Hearing loss linked to mental, physical, and social illnesses in older people

Hearing loss is the world's fourth-leading cause of years lived with disability. The condition may worsen an array of mental, physical, and social complications. As over 90% of hearing loss is age-related, its burden is notably growing amid aging populations.

21 Jul 2019

Hearing loss in older people linked to outdoor activity restriction, anxiety, memory loss

Hearing loss is the world's fourth-leading cause of years lived with disability. The condition may worsen an array of mental, physical, and social complications.

19 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Alzheimer's gene may affect cognitive health before adulthood, study finds

The Apolipoprotein E (APOE) is a major cholesterol carrier that aids in lipid transport and injury repair in the brain. It packages cholesterol and other fats and moves them through the bloodstream. APOE polymorphic alleles are the major genetic factors for the risk of Alzheimer’s disease (AD).

19 Jul 2019

Testosterone replacement therapy associated with increased risk of stroke, heart attack

Aging men with low testosterone levels who take testosterone replacement therapy are at a slightly greater risk of experiencing an ischemic stroke, transient ischemic attack, or myocardial infarction, especially during the first two years of use, reports a study appearing in The American Journal of Medicine, published by Elsevier.

18 Jul 2019