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Modern humans interbred with multiple Denisovan populations, suggests study

The findings are based on a new study led by Murray Cox from Massey University in New Zealand and made possible by sampling efforts led by Herawati Sudoyo from the Eijkman Institute for Molecular Biology in Jakarta, Indonesia.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Rare gut condition is more predictable from individual's genetic makeup, study finds

Hirschsprung disease - a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool - is more predictable from an individual's genetic makeup than previously envisioned.

11 Apr 2019

Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

New strategy for editing and repairing genetic mutation associated with microduplications

Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR/Cas9 and a seldom-used DNA repair pathway.

11 Apr 2019

German Research Foundation recently approves new research unit

"Cytomegalovirus, beware of this new research group!" This could be the motto of a new research unit recently approved by the German Research Foundation. It is titled: "Advanced concepts in cellular control of cytomegalovirus ".

11 Apr 2019

Genetics may play a role in developing cancer therapy-induced cardiomyopathy

Recent advances in the development of cancer therapies have increased long-term survival and prognosis.

10 Apr 2019

Researchers map genetic mutation behind incurable disease

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis.

10 Apr 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus.

9 Apr 2019

Researchers discover mechanism to form influenza A virus

The influenza A virus is known to form new strains every year. These strains are the result of small variations occurring at the level of the genome, which cause the virus to become different and no longer recognized by the immune system.

9 Apr 2019

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019

Study: Non-thermal plasma can inactivate 99.9% of dangerous airborne viruses

Dangerous airborne viruses are rendered harmless on-the-fly when exposed to energetic, charged fragments of air molecules, University of Michigan researchers have shown.

9 Apr 2019

'Battle royale' of oral pathogen helps explain how dangerous bacteria persist in hospital environment

Hundreds of different bacterial species are living inside your mouth. Some are highly abundant, while others are scarce. A few of these oral bacteria are known pathogens. Others are benign, or even beneficial.

9 Apr 2019

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals.

8 Apr 2019

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidad Carlos III de Madrid, the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz have led a study which demonstrates the viability of a gene editing strategy for recessive dystrophic epidermolysis bullosa (also known as butterfly chilidren) with the tool CRISPR/Cas9 in preclinical models with this disease.

8 Apr 2019

Genome News and Research

Modern humans interbred with multiple Denisovan populations, suggests study

Study describes vulnerability shared by large subset of cancer cell lines

Rare gut condition is more predictable from individual's genetic makeup, study finds

Researchers discover pathway contributing to fatty liver disease

New strategy for editing and repairing genetic mutation associated with microduplications

German Research Foundation recently approves new research unit

Genetics may play a role in developing cancer therapy-induced cardiomyopathy

Researchers map genetic mutation behind incurable disease

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers discover mechanism to form influenza A virus

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

Study: Non-thermal plasma can inactivate 99.9% of dangerous airborne viruses

'Battle royale' of oral pathogen helps explain how dangerous bacteria persist in hospital environment

Cellular protein could take on role of restriction factor for hepatitis B virus

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

Researchers discover how specific mutation obstructs healthy blood cell maturation

NYU biologists develop methods to validate gene regulatory networks

Researchers identify genetic mutations that can promote regeneration after liver damage

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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