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Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Overuse injuries - think muscle strains, tennis elbow, and rotator cuff tears - are a considerable problem in the United States, especially among young athletes.

30 Mar 2020

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure.

30 Mar 2020

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

By mining a vast trove of genetic data, researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients.

30 Mar 2020

Origins of SARS-CoV-2 – natural or man-made?

With over 780,000 individuals across the world infected and over 37,000 dead, the world is gripped by the pandemic caused by the novel strain of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

New blood test accurately detects more than 50 types of cancer

Researchers have developed a blood test that could accurately detect up to 50 types of cancers, and some of these detections could be even before the symptoms appear. The test would help physicians detect the origin or the source of cancer within the body explain the researchers from the European Society of Oncology. The study titled, "Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA," was published in the latest issue of the journal Annals of Oncology.

30 Mar 2020

Coronavirus shown to spread in high heat and humidity

A new study explores the possibility that the novel coronavirus, which is ravaging the world, can spread in hot and humid conditions, dispelling the view held by some investigators that the virus is more easily transmissible in colder climates.

30 Mar 2020

Drone delivers insulin for diabetic patient living in a remote community

The international medical team that accomplished the world's first documented drone delivery of insulin for a patient living in a remote community described the project in an ENDO 2020 abstract that will be published in the Journal of the Endocrine Society.

30 Mar 2020

Research shows significant difference in radiation response between sexes

Women undergoing radiotherapy for many cancers are more likely than men to be cured, but the side effects are more brutal, according to one of Australia's most experienced radiation oncology medical physicists.

30 Mar 2020

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

The direct oral anticoagulant rivaroxaban dramatically cut the likelihood of serious venous thromboembolism (VTE) in people recovering from lower limb orthopedic surgery requiring immobilization in comparison with enoxaparin, another anticoagulant agent, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Unraveling gut-to-brain communication paves way for targeted treatments

Scientists at Flinders University have, for the first time, identified a specific type of sensory nerve ending in the gut and how these may 'talk' to the spinal cord, communicating pain or discomfort to the brain.

30 Mar 2020

One third of cardiologists in the U.S. report being burnt out

More than 1 out of 3 heart doctors in the U.S. report feeling burned out, according to results of a new survey presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology

30 Mar 2020

Investigational drug vericiguat benefits patients with worsening heart failure

Patients with worsening heart failure and reduced ejection fraction who received the investigational drug vericiguat had a significantly lower rate of cardiovascular death or heart failure hospitalization compared with those receiving a placebo, based on research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

New microfluidic chip can mimic hypoxic conditions after a heart attack

Researchers led by biomedical engineers at Tufts University invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack - specifically when an artery is blocked in the heart and then unblocked after treatment.

30 Mar 2020

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too low.

30 Mar 2020

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Oral apixaban as effective as dalteparin for treating blood clots in people with cancer

For people with cancer, the oral blood thinner apixaban is at least as effective as dalteparin, a low molecular weight heparin given by injection, in preventing a repeat venous thromboembolism (VTE), or blood clot, with no excess in major bleeding events, according to Phase 3 trial results presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Taking ticagrelor alone better for patients with complex heart disease

Patients with complex heart disease who stopped taking aspirin three months after the insertion of one or more coronary stents and then took the anti-platelet medication ticagrelor alone for a year had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor over the same period.

30 Mar 2020

Study quantifies economic burden of CVD in women with a history of preterm delivery

A new study quantifies the future economic burden of cardiovascular disease (CVD) in women with a history of preterm delivery.

30 Mar 2020

10-year follow-up study shows safety, efficacy of stenting compared with bypass surgery

In a study with the longest follow-up to date of patients with a high-risk form of heart disease known as left main coronary artery disease (LMCAD), researchers found no significant differences in rates of death, heart attack or stroke between patients who were treated with a stent and those who underwent heart bypass surgery.

30 Mar 2020

Research News and Research

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

Origins of SARS-CoV-2 – natural or man-made?

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

New blood test accurately detects more than 50 types of cancer

Coronavirus shown to spread in high heat and humidity

Drone delivers insulin for diabetic patient living in a remote community

Research shows significant difference in radiation response between sexes

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

Unraveling gut-to-brain communication paves way for targeted treatments

One third of cardiologists in the U.S. report being burnt out

Investigational drug vericiguat benefits patients with worsening heart failure

New microfluidic chip can mimic hypoxic conditions after a heart attack

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

Oral apixaban as effective as dalteparin for treating blood clots in people with cancer

Taking ticagrelor alone better for patients with complex heart disease

Study quantifies economic burden of CVD in women with a history of preterm delivery

10-year follow-up study shows safety, efficacy of stenting compared with bypass surgery

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