Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Reduced radiation can maintain high cure rates in patients with HPV-related oropharyngeal cancers

Human papillomavirus-positive oropharynx cancers (cancers of the tonsils and back of the throat) are on rise.

27 Dec 2016

UCLA-led research finds promising results for more personalized head and neck cancer treatment

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

23 Dec 2016

Blocking protein that initiates immune response against viral infections may help combat HIV

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV.

23 Dec 2016

Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

Early-stage non-small cell lung cancer (NSCLC) patients with squamous cell carcinoma (SqCC) have a significantly higher rate of local failure after stereotactic body radiation therapy (SBRT) than other NSCLC histological subtypes.

23 Dec 2016

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany.

22 Dec 2016

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New data presented at the 2016 San Antonio Breast Cancer Symposium (SABCS) demonstrate that analyzing tumor biology with the Oncotype DX test can identify patients unlikely to benefit from chemotherapy prior to breast cancer surgery (neoadjuvant setting) and guide treatment decisions without compromising outcomes.

22 Dec 2016

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Clinical Genomics, a private company developing evidence-based diagnostic tools for colorectal cancer, today announced the launch of Colvera, a blood-based test for colorectal cancer (CRC) recurrence monitoring. Colvera is the result of a decade of research, development and clinical validation in more than 4,000 patients.

22 Dec 2016

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.

21 Dec 2016

Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

Nearly three years of research have brought about remarkable results for the majority of 80 patients subjected to targeted alpha therapy of metastatic prostate cancer.

21 Dec 2016

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

Clarity, a global international scientific research company, based in Austin, Texas, announces the latest results of its IRB-approved OPERA study.

21 Dec 2016

Sanford study explores protein's role in improving survival of ovarian cancer patients

A Sanford Research lab is studying a protein's role in improving survival in ovarian cancer patients. Findings published in Oncogenesis indicate a higher level of a specific protein correlates with an increased survival rate and decrease in the spreading of cancer cells.

21 Dec 2016

AXT makes magnetic particle imaging technology available to researchers in Australia

AXT is proud to be able to bring another cutting-edge technology to Australia that will help our medical researchers accelerate the rate at which they bring new cures, remedies and therapies to clinical realities.

From AXT Pty Ltd 21 Dec 2016

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.

20 Dec 2016

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology.

20 Dec 2016

New SWOG review shows vitamin E and selenium do not prevent colorectal adenomas

Eight years ago, results from a landmark cancer prevention trial run by SWOG showed that a daily dose of vitamin E and selenium did not prevent prostate cancer.

20 Dec 2016

Regular NSAID use linked to increased risk of endometrial cancer mortality

Regular use of over-the-counter non-steroidal inflammatory drugs such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with Type 1 endometrial cancers, according to a new population-based study led by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

20 Dec 2016

FDA awards accelerated approval to new ovarian cancer drug

The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer.

19 Dec 2016

Oncology News and Research

Further Reading

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Reduced radiation can maintain high cure rates in patients with HPV-related oropharyngeal cancers

UCLA-led research finds promising results for more personalized head and neck cancer treatment

Blocking protein that initiates immune response against viral infections may help combat HIV

Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Generative AAE can be radically new way to discover drugs on demand

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

Sanford study explores protein's role in improving survival of ovarian cancer patients

AXT makes magnetic particle imaging technology available to researchers in Australia

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Novel genomics model allows personalized approach to radiation therapy

New SWOG review shows vitamin E and selenium do not prevent colorectal adenomas

Regular NSAID use linked to increased risk of endometrial cancer mortality

FDA awards accelerated approval to new ovarian cancer drug

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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