Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Novel computational tool helps scientists detect hidden cell types behind disease

Cells throughout the body work together like singers in a choir to keep us healthy, as long as they work in perfect harmony.

7 Apr 2025

Immigration crackdowns disrupt the caregiving industry. Families pay the price.

Alanys Ortiz reads Josephine Senek's cues before she speaks. Josephine, who lives with a rare and debilitating genetic condition, fidgets her fingers when she's tired and bites the air when something hurts.

4 Apr 2025

NUZ-001 shows positive results in human 3D brain model

Neurizon Therapeutics Limited (“Neurizon”), a clinical-stage biotech company dedicated to advancing treatments for neurodegenerative diseases, is pleased to advise that results from an independent study undertaken in collaboration with Tessara Therapeutics (“Tessara”) will be presented by the group’s Principal Scientist and Alzheimer’s Disease expert, Dr Mark Greenough at the AD/PD 2025 Advances in Sciences & Therapy conference on April 2nd to 3rd.

3 Apr 2025

Neuropathological basis of visual dysfunction in rare Alzheimer's forms

Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer's disease, finds a new study by UCL researchers.

3 Apr 2025

New drug shows neuroprotective and anti-inflammatory effects in murine models of Alzheimer's

Alzheimer's disease, the most common cause of dementia, is currently incurable. The current drugs available have very limited efficacy and only in mild stages of the disease.

2 Apr 2025

Senolytics offer hope for more precise Alzheimer's treatments

A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled "Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer's disease."

1 Apr 2025

Study links low LDL-C levels to reduced risk of dementia

People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, including lower risk of Alzheimer's disease related dementia, shows a study published online today in the Journal of Neurology Neurosurgery & Psychiatry.

1 Apr 2025

Weight training shields the brain from dementia in older adults

The benefits of weight training are many: it promotes gains in strength and muscle mass, reduces body fat, and contributes to well-being and mental health.

1 Apr 2025

Virtual reality offers new approach for early Alzheimer's detection

Most people donning virtual reality (VR) goggles are seeking the thrill of being immersed in a fictitious video game world. But some are donning them for an entirely different experience: to help researchers identify those most at risk of developing Alzheimer's disease.

1 Apr 2025

A new blood test could improve how Alzheimer’s disease is diagnosed

The blood test for eMTBR-tau243 shows strong correlation with tau pathology, enhancing Alzheimer's diagnosis and monitoring cognitive decline effectively.

1 Apr 2025

Mayo Clinic launches study to investigate rapidly progressive dementia in Alzheimer's

Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades.

1 Apr 2025

Study helps characterize how sleep deficiency may relate to Alzheimer's pathogenesis

New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over time.

31 Mar 2025

Blood test offers insight into Alzheimer's stage and severity

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

31 Mar 2025

Novel PET imaging method quantifies brain inflammation enzyme

A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research published in the March issue of The Journal of Nuclear Medicine.

28 Mar 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

Auburn researchers discover fundamental principle of how brain cells stay connected

Scientists at Auburn University have uncovered a fundamental principle of how brain cells stay connected, and their discovery could change how we understand Alzheimer's disease.

27 Mar 2025

Neighborhood disadvantage linked to higher dementia risk

People living in more disadvantaged neighborhoods may be more likely to develop dementia than people living in neighborhoods with fewer disadvantages, according to a study published on March 26, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

26 Mar 2025

New open-source tool identifies aging cells to help fight chronic diseases

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer's disease and other chronic diseases.

25 Mar 2025

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

A study in Alzheimer's & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).

25 Mar 2025

ADHD may be linked to increased risk of developing dementia later in life

An adult brain affected by attention deficit disorder with or without hyperactivity (ADHD) presents modifications similar to those observed in individuals suffering from dementia.

25 Mar 2025