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Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

In a recent study posted to the bioRxiv* preprint server, researchers presented the intragenomic rearrangements of β-coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

9 Mar 2022

A new view of SARS-CoV-2 genome structure

Researchers performed DMS mutational profiling with sequencing and DREEM clustering to determine the SARS-CoV-2 RNA secondary structure.

8 Mar 2022

Study identifies new immune checkpoint that may be exploited for cancer treatment

A collaborative study led by the Monash Biomedicine Discovery Institute has discovered a new immune checkpoint that may be exploited for cancer therapy.

8 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Peripubertal stress leads to increase in adipose tissue and reduces sociability

Between the end of childhood and the beginning of adolescence, there is a critical window of time referred to as "peripuberty".

2 Mar 2022

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

COVID-19 severity is correlated with body composition

In a recent study posted to the medRxiv* preprint server, researchers assessed the effect of changes in the abdominal well-being and physique on coronavirus disease 2019 (COVID-19) severity using magnetic resonance imaging (MRI).

28 Feb 2022

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

In a recent study, researchers evaluated the effect of COVID-19 vaccines on the symptomatic prevalence of SARS-CoV-2 infections beyond the acute phase of the disease.

28 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

Cellular automata imaging-based classification of SARS-CoV-2 variants

A new preprint classified and grouped SARS-CoV-2 variants based on their cellular automata imaging images and Hamming distances, to determine viral evolutions.

22 Feb 2022

TTUHSC expert wins NIH renewal grant to continue research on neurological disorders

According to the Global Burden of Disease study, neurological disorders are the leading cause of disability and the second leading cause of death after heart disease.

21 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

Combating leukemia cells by disrupting their energy maintenance mechanism

Acute myeloid leukemia, which affects blood and bone marrow cells, is a particularly dangerous form of cancer. More than half of patients under the age of 60 die.

17 Feb 2022

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Researchers examined patients with pulmonary PASC of SARS-CoV-2 to determine the frequency and function of SARS-CoV-2-specific T cells in their blood.

17 Feb 2022

Innovative coating kills SARS-CoV-2 and E. coli

Researchers develop a low-cost, non-toxic, and scalable antimicrobial polymer that can be functionalized on diverse fabrics.

16 Feb 2022

Developing nanoplatforms for direct drug delivery to T cells

T cells, also known as lymphocytes, have important roles in various immune reactions. However, there are only a few reports on delivery systems into T cells. Realizing this, it is essential to work and actively contribute in controlling immune systems.

16 Feb 2022

Intracellular News and Research

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

A new view of SARS-CoV-2 genome structure

Study identifies new immune checkpoint that may be exploited for cancer treatment

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Peripubertal stress leads to increase in adipose tissue and reduces sociability

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

COVID-19 severity is correlated with body composition

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

Melatonin as a safe and potentially life-saving treatment for COVID-19

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Cellular automata imaging-based classification of SARS-CoV-2 variants

TTUHSC expert wins NIH renewal grant to continue research on neurological disorders

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Research shows alterations in transfer RNAs at the epigenetic level in cancer

Combating leukemia cells by disrupting their energy maintenance mechanism

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Innovative coating kills SARS-CoV-2 and E. coli

Developing nanoplatforms for direct drug delivery to T cells

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