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New test can tell if you are immune to SARS-CoV-2

In a recent study published in the journal Nature Biotechnology, an international team of researchers developed and evaluated quantitative polymerase chain reaction (qPCR)-based assays to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific functional T cell immunity.

15 Jun 2022

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness.

13 Jun 2022

Potential applications of bioactive molecules present in fruit peels

A recent study published in Current Issues in Molecular Biology reviewed the potential biological applications of fruit peel extracts.

13 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Researchers generated an AI resource to characterize the T cell epitope landscape for SARS-CoV-2 variants of concern.

9 Jun 2022

Study describes one of the first entirely new drug delivery microencapsulation approaches in decades

A new study from the University of Michigan describes one of the first entirely new drug delivery microencapsulation approaches in decades.

8 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.

6 Jun 2022

ASU study explores components of the immune system

Unless you are an identical twin, you probably aren't often mistaken for someone else. Likewise, our own sense of self as distinct from all other humans is deeply ingrained since early childhood.

2 Jun 2022

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Researchers identified a single viral gene product, the accessory factor ORF7a, facilitating SARS-CoV-2 immune evasion by downregulating the surface expression of MHC class I molecules.

1 Jun 2022

The immunogenicity and safety of the adjuvanted recombinant protein vaccine Sanofi/GSK-D614 or -B.1.351 administered as a heterologous booster dose

Researchers assessed the safety and immunogenicity of SARS-CoV-2 booster vaccines.

31 May 2022

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major histocompatibility complex class I (MHC-I) in hosts.

30 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.

24 May 2022

Peptides News and Research

New test can tell if you are immune to SARS-CoV-2

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Potential applications of bioactive molecules present in fruit peels

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Study describes one of the first entirely new drug delivery microencapsulation approaches in decades

De novo-designed mini-protein against SARS-CoV-2

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

ASU study explores components of the immune system

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

The immunogenicity and safety of the adjuvanted recombinant protein vaccine Sanofi/GSK-D614 or -B.1.351 administered as a heterologous booster dose

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Natural immunity weak and short-lived in unvaccinated after Omicron infection

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

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