Platelets News and Research

RSS

Research findings open up possibility for developing potent anti-clotting drugs

Researchers at the University of Illinois at Chicago have discovered a molecular switch that causes small, beneficial clots that stop bleeding to enlarge further during wound healing. By blocking this switch in lab mice, the researchers prevented small clots from growing -- a process that can pose a danger in humans -- while preserving their ability to staunch bleeding

29 Oct 2013

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

An investigational new PARP inhibitor, BMN 673, is showing early responses in patients with heavily pretreated, advanced, BRCA-related cancers of the breast and ovary, according to phase I clinical trial results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

23 Oct 2013

FDA approves SC formulation of Genentech's Actemra for rheumatoid arthritis

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has approved a subcutaneous formulation of Actemra (tocilizumab) for the treatment of adults with moderately to severely active rheumatoid arthritis who have used one or more disease-modifying antirheumatic drugs, such as methotrexate, that did not provide enough relief.

22 Oct 2013

Detecting dangerous blood clots in the form of simple urine test

Detecting dangerous blood clots, which can cause life-threatening conditions such as strokes and heart attacks, leading causes of death for men and women in the U.S., has been a coveted and elusive goal.

17 Oct 2013

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation , today announced the results of the MPACT phase III clinical trial of ABRAXANE® in combination with gemcitabine were published online in the October 16th edition of the New England Journal of Medicine.

17 Oct 2013

Ticagrelor drug may reduce risk of dying following heart attack

Scientists from the University of Sheffield have discovered ground breaking clues as to how the pioneering heart drug ticagrelor might reduce the risk of dying following a heart attack, in comparison to previous standard treatments.

16 Oct 2013

DIM compound derived from cruciferous vegetable protects rodents from radiation doses

Georgetown University Medical Center researchers say a compound derived from cruciferous vegetable such as cabbage, cauliflower and broccoli protected rats and mice from lethal doses of radiation.

15 Oct 2013

Understanding the biological players in clot formation could lead to new thrombotic therapies

Ulhas Naik, professor of biological sciences and director of the Delaware Cardiovascular Research Center, pores over laboratory data on his computer, even during breakfast most mornings. He is on a quest to tease out the roles that various blood components play in the formation of clots.

9 Oct 2013

New research identifies protein that controls formation of different types of mature blood cells

New research in the Journal of Experimental Medicine identifies a protein that controls the formation of different types of mature blood cells - a finding that could be important to developing new treatments for blood diseases and helping realize the potential of regenerative medicine.

8 Oct 2013

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress (ECC2013) heard today.

1 Oct 2013

Researchers discover how aspirin improves survival in patients with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress heard today (Monday).

30 Sep 2013

Ohio State's Heart and Vascular Center names Garret FitzGerald as recipient of Schottenstein Prize

The Ohio State University Wexner Medical Center's Heart and Vascular Center has named Dr. Garret FitzGerald, professor of Medicine and Pharmacology; chair of the Department of Pharmacology and director of the Institute for Translational Medicine and Therapeutics at the Perelman School of Medicine at University of Pennsylvania, the recipient of the 2013 Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences.

26 Sep 2013

FDA approves use of abraxane to treat patients with late-stage pancreatic cancer

The U.S. Food and Drug Administration today expanded the approved uses of Abraxane (paclitaxel protein-bound particles for injectable suspension, ablumin-bound) to treat patients with late-stage (metastatic) pancreatic cancer.

7 Sep 2013

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Rigel Pharmaceuticals, Inc. today announced its plans to focus the Company's resources on the completion of three lead clinical programs. These efforts include commencing a Phase 3 clinical study of fostamatinib, an oral SYK inhibitor, in Immune Thrombocytopenic Purpura pending discussions with regulatory agencies.

5 Sep 2013

Golgi apparatus: New target for treatment of acute cerebral infarction

Expression of soluble CD40L has been shown to increase sig-nificantly in conditions such as stroke, myocardial infarction, unstable angina, high cholesterol, or other cardiovascular events. 95% of the circulating CD40L exists in activated platelets.

5 Sep 2013

Scientists develop new form of aspirin to cope with resistance

Scientists are reporting development of a new form of aspirin - taken daily by about 60 million people in the United States alone to reduce the risk of heart attack and stroke - that could extend aspirin's benefits to people who may not respond to the drug. Their advance toward coping with "aspirin resistance" appears in the journal ACS Nano.

5 Sep 2013

Increased risk caused by smoking is completely reversed after smoking cessation

Dr Dohi said: "Smokers are twice as likely to have a heart attack as people who have never smoked. Quitting smoking is the most important thing people can do to reduce their risk of cardiovascular disease. But until now, studies have not examined whether the increased risk caused by smoking is completely reversed after smoking cessation."

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Findings could alter ways in which doctors use platelets to treat traumatic injuries

A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections.

2 Sep 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

Platelets News and Research

Research findings open up possibility for developing potent anti-clotting drugs

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

FDA approves SC formulation of Genentech's Actemra for rheumatoid arthritis

Detecting dangerous blood clots in the form of simple urine test

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Ticagrelor drug may reduce risk of dying following heart attack

DIM compound derived from cruciferous vegetable protects rodents from radiation doses

Understanding the biological players in clot formation could lead to new thrombotic therapies

New research identifies protein that controls formation of different types of mature blood cells

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Researchers discover how aspirin improves survival in patients with colon cancer

Ohio State's Heart and Vascular Center names Garret FitzGerald as recipient of Schottenstein Prize

FDA approves use of abraxane to treat patients with late-stage pancreatic cancer

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Golgi apparatus: New target for treatment of acute cerebral infarction

Scientists develop new form of aspirin to cope with resistance

Increased risk caused by smoking is completely reversed after smoking cessation

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Findings could alter ways in which doctors use platelets to treat traumatic injuries

New angle for developing drugs to prevent thrombosis and heart attack

Latest eBooks

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms