Spike Protein News and Research

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Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Researchers conducted an in vitro analysis to assess the host cell furin-mediated cleavability of the spike protein of the SARS-CoV-2 Omicron (B.1.529) variant.

26 Apr 2022

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

The new study, published in the journal Vaccines, reports on an attempt to use the SARS-CoV-2 spike subunit protein to elicit an immune reaction.

26 Apr 2022

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

A new study discusses the potential of certain plant compounds to block SARS-CoV-2 replication within host cells.

24 Apr 2022

Antibody escape in SARS-CoV-2 Omicron spike protein

Researchers examined antibody escape and cross-domain stabilization in the SARS-CoV-2 Omicron spike protein.

22 Apr 2022

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

Researchers compared the efficiency of monovalent and bivalent mRNA vaccines against SARS-CoV-2.

22 Apr 2022

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

A new study describes the impact of SARS-CoV-2 on host lipid metabolism.

21 Apr 2022

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

A new study shows that it is possible to use the genetic sequences of a person's antibodies to predict what pathogens those antibodies will target.

21 Apr 2022

Evolution of SARS-CoV-2 variants

Research has demonstrated the evolutionary process and biology of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic.

21 Apr 2022

Antibody response to Pfizer-BioNTech COVID-19 vaccine over 6 months

A new study published in PLoS ONE characterizes the antibody response to BNT162b2, the Pfizer-BioNTech COVID-19 vaccine

20 Apr 2022

Novel saliva immunoassays to detect prior SARS-CoV-2 infection

Six salivary ELISAs were developed to evaluate the immune response to SARS-CoV-2 and estimate rates of past infection.

20 Apr 2022

Polyethylene glycol-specific antibody responses induced by mRNA-1273 COVID-19 vaccine

Researchers determined the impact of COVID-19 vaccines on polyethylene glycol-specific antibody responses.

20 Apr 2022

Study investigates co-metabolism during SARS-CoV-2 infection

In a new study, researchers investigated host-virus co-metabolism during a SARS-CoV-2 infection.

20 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

Study investigates the production of a virosome-based COVID-19 vaccine candidate

In a new study, different signal peptides, baculovirus transfer vectors, cell lines, infection techniques, and formulation buffers were investigated with the purpose of building a scalable bioprocess to generate high-quality S protein for incorporation in a virosome-based COVID-19 vaccine candidate.

18 Apr 2022

Spike Protein News and Research

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

A novel mouse model to test SARS-CoV-2 viral infection

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

The challenges of Omicron

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

Antibody escape in SARS-CoV-2 Omicron spike protein

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

Evolution of SARS-CoV-2 variants

Antibody response to Pfizer-BioNTech COVID-19 vaccine over 6 months

Novel saliva immunoassays to detect prior SARS-CoV-2 infection

Polyethylene glycol-specific antibody responses induced by mRNA-1273 COVID-19 vaccine

Study investigates co-metabolism during SARS-CoV-2 infection

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

Study investigates the production of a virosome-based COVID-19 vaccine candidate

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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