Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Research shows PODXL protein contributes to aggressive forms of bladder cancer

Aggressive forms of bladder cancer involve the protein PODXL - a discovery that could hold the key to improved treatment, according to researchers at Lund University, Uppsala University and KTH in Sweden.

24 May 2013

Common type of childhood asthma is not related to allergens and inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center and SUNY Downstate Medical Center has revealed the roots of a common type of childhood asthma, showing that it is very different from other asthma cases.

24 May 2013

Drug addiction can be visualized in specific regions of brain that determine decision-making

New research shows that craving drugs such as nicotine can be visualized in specific regions of the brain that are implicated in determining the value of actions, in planning actions and in motivation.

24 May 2013

Researchers reveal roots of a common type of childhood asthma

24 May 2013

Mayo Clinic, Cancer Genetics form joint venture to improve cancer care

Mayo Clinic and Cancer Genetics Inc. today launched OncoSpire Genomics, a joint venture with the singular goal of improving cancer care by discovering and commercializing diagnostic tests that leverage next-generation sequencing.

23 May 2013

Cognoptix' SAPPHIRE II eye test identifies Alzheimer's disease patients via Ab signature in the eyes

Cognoptix, an emerging medical device company, announced today that its SAPPHIRE II eye test identified Alzheimer's disease patients via a beta amyloid ("Ab") signature in their eyes in a 10-subject proof-of-concept clinical trial.

23 May 2013

Cancer experts to discuss latest developments and implications of cell therapies in oncology

John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 cancer centers, will bring together leading cancer experts, for presentation and discussion of the latest developments and implications of cell therapy and interventional immunology in oncology, on Friday, June 7 from 7:00am to 1:30pm.

23 May 2013

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

We have done it. We have decreased the increase in the cost of healthcare. ... Is this decline the desperately needed bend in the healthcare cost curve or just the impact of the depressed economy? ... A slower growth of healthcare cost would mean less burden on the individual family, freeing that family to invest in and live a higher quality of life.

22 May 2013

Caltech biologists show that microRNA-146a protects stem cells during inflammation

When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer.

22 May 2013

Alzheimer's disease: Researchers find new drug to prevent, treat the disease

Researchers at USC have found that a class of pharmaceuticals can both prevent and treat Alzheimer's Disease in mice.

22 May 2013

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day.

21 May 2013

Researchers pinpoint catalytic trigger for onset of Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease - when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.

21 May 2013

PathCentral releases APLIS platform to serve the needs of community pathologist

PathCentral, a technology-enabled company dedicated to the success of the pathology community, today introduced AP Anywhere, its bundled Anatomic Pathology Laboratory Information System technology offering.

20 May 2013

Quest Diagnostics completes acquisition of Concentra's toxicology and clinical laboratory business

Quest Diagnostics, the world's leading provider of diagnostic information services, announced today that it has acquired the toxicology and clinical laboratory business of medical center operator Concentra, a subsidiary of Humana Inc.

From Quest Diagnostics 20 May 2013

Study: VEGF inhibitor appears to improve glaucoma surgical outcomes

The most common cause of failure after glaucoma surgery is scarring at the surgical site, so researchers are actively looking for ways to minimize or prevent scar formation. Previous work had suggested that vascular endothelial growth factor (VEGF) activates fibrosis, whereas VEGF inhibition results in reduced scar formation and better surgical results.

18 May 2013

Alnylam reports pre-clinical data from ALN-AS1 program for treatment of AIP

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented key pre-clinical proof-of-concept data from its RNAi therapeutic program targeting aminolevulinate synthase-1 (ALAS-1) for the treatment of porphyria including acute intermittent porphyria.

18 May 2013

Protein processing breakdown in endoplasmic reticulum

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning.

17 May 2013

Scientists reveal inside story of European regulatory review and approval of Glybera

The scientists who led the team that developed Glybera, the first gene therapy drug approved for use in the Western world, provide a fascinating first-person account of their pioneering work in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 May 2013

Breathing motor vehicle emissions triggers change in HDL cholesterol

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.

16 May 2013

Secure cloud-based computing system to access, analyze human genomic cancer information

The University of Chicago launched the first secure cloud-based computing system that enables researchers to access and analyze human genomic cancer information without the costly and cumbersome infrastructure normally needed to download and store massive amounts of data.

16 May 2013

Pathology News and Research

Further Reading

Research shows PODXL protein contributes to aggressive forms of bladder cancer

Common type of childhood asthma is not related to allergens and inflammation

Drug addiction can be visualized in specific regions of brain that determine decision-making

Researchers reveal roots of a common type of childhood asthma

Mayo Clinic, Cancer Genetics form joint venture to improve cancer care

Cognoptix' SAPPHIRE II eye test identifies Alzheimer's disease patients via Ab signature in the eyes

Cancer experts to discuss latest developments and implications of cell therapies in oncology

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

Caltech biologists show that microRNA-146a protects stem cells during inflammation

Alzheimer's disease: Researchers find new drug to prevent, treat the disease

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Researchers pinpoint catalytic trigger for onset of Alzheimer's disease

PathCentral releases APLIS platform to serve the needs of community pathologist

Quest Diagnostics completes acquisition of Concentra's toxicology and clinical laboratory business

Study: VEGF inhibitor appears to improve glaucoma surgical outcomes

Alnylam reports pre-clinical data from ALN-AS1 program for treatment of AIP

Protein processing breakdown in endoplasmic reticulum

Scientists reveal inside story of European regulatory review and approval of Glybera

Breathing motor vehicle emissions triggers change in HDL cholesterol

Secure cloud-based computing system to access, analyze human genomic cancer information

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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