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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

OXGENE™ reports third consecutive year of 100% year on year revenue growth

OXGENE™ has more than doubled its annual revenue in the financial year just closed, in the third consecutive year of 100% year on year revenue growth.

From OXGENE 6 May 2020

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

The reason why we sleep remains an unresolved question of the 21st century. Research by Sara Marie Ulv Larsen, Sebastian Camillo Holst and colleagues from the Neurobiology Research Unit at the University Hospital Copenhagen, published this week in the open access journal PLoS Biology, now shows that the depth of non-rapid-eye-movement (nonREM) sleep in humans is associated with different genetic versions of a gene that encodes a water channel involved in fluid flow in the brain.

6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

New tool may offer a novel approach to prevent multiple chronic diseases

A study just released by Columbia University Mailman School of Public Health is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year.

6 May 2020

Study provides more insight into the initiation and progression of human cancers

Volume 11, Issue 18 of @Oncotarget Clinical implications of chromatin accessibility assessed by ATAC-seq profiling in human cancers especially in a large patient cohort is largely unknown.

6 May 2020

Researchers discover new gene involved in regulating the body's cholesterol

Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision -- or developing new drugs -- requires knowing which genes are involved in disease.

4 May 2020

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Cytosurge AG, a company manufacturing unique high-precision nanotechnology instruments, announced that they will collaboratively investigate CRISPR-based approaches to more effectively introduce multiple edits into the genome of single cells, while minimizing CRISPR-related toxicity.

4 May 2020

Scientists develop CRISPR-based test for SARS-CoV-2

Now, a team of scientists at the University of California Santa Barbara has developed a low-cost, rapid, and high-tech test that can detect SARS-CoV-2 effectively. They have developed a CRISPR-based test that is sensitive and effective as traditional tests.

4 May 2020

Researchers discover neural circuit that drives physical responses to emotional stress

Researchers at Nagoya University have discovered a neural circuit that drives physical responses to emotional stress.

4 May 2020

Scientists develop new way to deliver molecules that target specific genes within cells

A group of researchers from University of Toronto Engineering and SickKids Hospital have developed a new way to deliver molecules that target specific genes within cells.

4 May 2020

Individuals with high risk of cancer and CVD cannot be identified based on family history

Certain genetic changes, termed "pathogenic variants," substantially increase risk for cardiovascular disease and cancer--the leading causes of death--but testing to identify individual carriers is not part of current clinical practice.

4 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body.

3 May 2020

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

A team of Chinese scientists have reported the high-resolution cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2, the infective virus of COVID-19.

3 May 2020

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Researchers at EMBL's European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute analysed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

2 May 2020

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

In this interview, Dr. Polinski and Dr. Atabakhsh discuss the importance of developing biomarkers for Parkinson’s and the partnership between MJFF and Abcam.

From Abcam 1 May 2020

Multicolor Immunohistochemistry (IHC): Going Beyond a Single Color

An interview with Dr. Will Howat at SfN 2018, discussing the possibilities and challenges of immunohistochemistry (IHC) beyond a single color!

From Abcam 1 May 2020

Scientists generate molecular models of compounds relevant for COVID-19

The discovery of suitable drugs that could help treat diseases is a long process. However, computer-aided drug design and simulation could speed up the process and also increase the possibilities say experts. This form of drug design and simulation could soon be the gold standard in drug development.

30 Apr 2020

Study finds abnormal alternative RNA splicing patterns in aggressive prostate cancer

Aggressive forms of prostate cancer don't act the way they should, hanging on to genetic materials called introns that should be thrown away, a new six-year study led by Dean Tang, Ph.D., and Song Liu, Ph.D., of Roswell Park Comprehensive Cancer Center has revealed.

30 Apr 2020

SU2C commends FDA’s approval of new cancer therapy

Stand Up To Cancer (SU2C) welcomed the recent Food and Drug Administration (FDA) approval this month of encorafenib in combination with cetuximab for patients with advanced BRAF-mutated colorectal cancer.

30 Apr 2020

DNA News and Research

Further Reading

OXGENE™ reports third consecutive year of 100% year on year revenue growth

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

New tool may offer a novel approach to prevent multiple chronic diseases

Study provides more insight into the initiation and progression of human cancers

Researchers discover new gene involved in regulating the body's cholesterol

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Scientists develop CRISPR-based test for SARS-CoV-2

Researchers discover neural circuit that drives physical responses to emotional stress

Scientists develop new way to deliver molecules that target specific genes within cells

Individuals with high risk of cancer and CVD cannot be identified based on family history

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

Multicolor Immunohistochemistry (IHC): Going Beyond a Single Color

Scientists generate molecular models of compounds relevant for COVID-19

Study finds abnormal alternative RNA splicing patterns in aggressive prostate cancer

SU2C commends FDA’s approval of new cancer therapy

Understanding the DNA Damage Response in Innate Immunity eBook

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