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Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Results from the National Institutes of Health's Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study show that sildenafil (Viagra) and tadalafil (Cialis) may not be suitable candidates for treating dementia.

4 Oct 2022

Model simulations for use of rapid antigen testing for COVID-19 diagnosis

In new research, researchers overviewed the impact of rapid antigen tests use cases with and without surveillance; hospital-based screening to decrease nosocomial COVID-19, and COVID-19 testing to enable prompt and expanded treatment for different country settings.

4 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

What are the challenges of COVID-19 vaccination and herd immunity?

A new study reviewed the challenges of coronavirus disease 2019 (COVID-19) vaccination and herd immunity.

4 Oct 2022

What are the genetic associations of stroke pathogenesis across ancestry groups?

In new research, researchers identified genetic associations of stroke pathogenesis.

4 Oct 2022

BU neuroscientists hope to uncover new ways to treat memory-related disorders

You may not realize it, but each time you recall a memory - like your first time riding a bike or walking into your high school prom - your brain changes the memory ever so slightly.

3 Oct 2022

ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

Study: Fewer Black, Hispanic and Asian patients qualify for treatments that slow Alzheimer's progression

The development of anti-amyloid monoclonal antibodies that may slow the progression of Alzheimer's disease by breaking down amyloid plaques, a hallmark of the disease, has brought fresh hope to aging populations and the doctors who treat them.

3 Oct 2022

Researchers discover a molecule that promotes tumor cell survival in retinoblastoma

Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer.

3 Oct 2022

Labconco awarded a national group purchasing agreement with Premier, Inc.

Labconco has been awarded a group purchasing agreement for IV Hoods (Primary Engineering Controls) with Premier, Inc.

From Labconco 3 Oct 2022

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

Researchers investigated the use of aminoadamantane nitrate compounds as anti-SARS-CoV-2 drugs.

3 Oct 2022

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

Researchers demonstrated clinical features and infectivity of the currently dominant SARS-CoV-2 variant of concern Omicron, compared to Delta, the previously dominant VOC.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Universal vaccine advancement through AI and recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng and Dr. Lurong Pan about how AI computing can be used in combination with high throughput production and screening to enhance the development process for potential universal vaccines.

From Sino Biological Inc. 3 Oct 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

Gut microbiome could contribute to a person's risk for HIV infection, research suggests

New UCLA-led research suggests certain gut bacteria -- including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected.

30 Sep 2022

Oxytocin induces epicardial cell proliferation, study finds

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

30 Sep 2022

Gut microbiome likely to contribute to HIV infection

30 Sep 2022

Patients with scleroderma have reduced levels of Cathepsin L

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients.

30 Sep 2022

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Drugs News and Research

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Model simulations for use of rapid antigen testing for COVID-19 diagnosis

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

What are the challenges of COVID-19 vaccination and herd immunity?

What are the genetic associations of stroke pathogenesis across ancestry groups?

BU neuroscientists hope to uncover new ways to treat memory-related disorders

ASU scientists discover an unusual RNA biogenesis pathway

Study: Fewer Black, Hispanic and Asian patients qualify for treatments that slow Alzheimer's progression

Researchers discover a molecule that promotes tumor cell survival in retinoblastoma

Labconco awarded a national group purchasing agreement with Premier, Inc.

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Universal vaccine advancement through AI and recombinant technology

The compositional and functional diversity of the gut fungal microbiome

Gut microbiome could contribute to a person's risk for HIV infection, research suggests

Oxytocin induces epicardial cell proliferation, study finds

Gut microbiome likely to contribute to HIV infection

Patients with scleroderma have reduced levels of Cathepsin L

Study reveals the role of autophagy in competitive elimination of cancer cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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