Clinical Trial News and Research

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Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Swallowing difficulties, or dysphagia, affect up to 80% of people with Parkinson's disease and can lead to serious complications, including malnutrition, aspiration and reduced quality of life.

24 Nov 2025

Study introduces cost-effective approach to analyze entire T-cell repertoire

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital.

24 Nov 2025

Scientists reverse aging in blood stem cells by restoring lysosome function

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

24 Nov 2025

Vegan diet with unhealthy plant foods promotes greater weight loss than Mediterranean diet

Eating a vegan diet increases consumption of plant-based foods-including those defined as "unhealthy" by the plant-based diet index-leading to greater weight loss than the Mediterranean diet, finds a new analysis by the Physicians Committee for Responsible Medicine published in Frontiers in Nutrition.

24 Nov 2025

New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer

Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.

24 Nov 2025

World’s first experimental lung cancer vaccine to enter clinical trials

People at high risk of lung cancer will soon be able to receive the first ever experimental vaccine designed to prevent the disease, in a world-first clinical trial led by researchers at UCL and the University of Oxford.

22 Nov 2025

Inflammation control can protect against AMD-like retinal damage

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models.

21 Nov 2025

New trial to test extended tranexamic acid use for faster ACL surgery recovery

A breakthrough could be coming in the way young people recover from surgery to reconstruct the anterior cruciate ligament (ACL) in the knee, a common sports injury.

21 Nov 2025

Diet swap alters breast milk composition within six days

Swapping beef for a plant-based meat substitute changed breast milk composition in just six days - even when the rest of the diet was made up of whole, unprocessed foods - according to a first-of-its-kind study from researchers at The University of Texas at Austin.

21 Nov 2025

Study suggests cannabis may temporarily curb alcohol consumption

The "California sober" trend, which involves ditching alcohol in favor of cannabis, is gaining momentum, spreading from Hollywood to health influencers to homes across America.

21 Nov 2025

Cancer stole her voice. She used AI, curse words, and kids’ books to get it back.

When doctors told her they had to remove her tongue and voice box to save her life from the cancer that had invaded her mouth, Sonya Sotinsky sat down with a microphone to record herself saying the things she would never again be able to say.

21 Nov 2025

Eating lean beef as part of MED diet could improve gut diversity

Incorporating lean beef into a Mediterranean diet reduces TMAO levels and improves gut health, highlighting the importance of dietary patterns for wellness.

21 Nov 2025

Engineered CAR-T cells show promise against glioblastoma in preclinical models

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

20 Nov 2025

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

Public interest in drugs known as glucagon-like peptide-1 receptor agonists, also called GLP-1 RAs, has surged in recent years, with popular types like semaglutide (sold under brand names like Ozempic and Wegovy) becoming known for their weight-loss effects.

20 Nov 2025

Structured infection prevention program can save mothers’ lives in low-resource settings

A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women's lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.

19 Nov 2025

Lean beef fits safely into a Mediterranean diet without raising heart disease risk

Eating moderate amounts of lean beef as part of a Mediterranean diet does not increase an emerging risk factor for cardiovascular disease, according to a new study by an interdisciplinary research team at Penn State.

19 Nov 2025

AI analysis of biopsy slides predicts rectal cancer treatment response

Artificial intelligence (AI) can predict how well patients with rectal cancer will respond to treatment by analyzing standard tissue samples taken during diagnosis, finds a new study from researchers at UCL and UCLH.

19 Nov 2025

New clinical trial shows promise for shorter TB treatment

New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."

19 Nov 2025

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

18 Nov 2025

New AI investment aims to accelerate the search for an effective HIV vaccine

As of 2024, over 40 million people in the world are diagnosed with human immunodeficiency virus (HIV)-a chronic, life-threatening infection that remains one of the leading global causes of death.

18 Nov 2025

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Clinical Trial News and Research

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Study introduces cost-effective approach to analyze entire T-cell repertoire

Scientists reverse aging in blood stem cells by restoring lysosome function

Vegan diet with unhealthy plant foods promotes greater weight loss than Mediterranean diet

New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer

World’s first experimental lung cancer vaccine to enter clinical trials

Inflammation control can protect against AMD-like retinal damage

New trial to test extended tranexamic acid use for faster ACL surgery recovery

Diet swap alters breast milk composition within six days

Study suggests cannabis may temporarily curb alcohol consumption

Cancer stole her voice. She used AI, curse words, and kids’ books to get it back.

Eating lean beef as part of MED diet could improve gut diversity

Engineered CAR-T cells show promise against glioblastoma in preclinical models

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

Structured infection prevention program can save mothers’ lives in low-resource settings

Lean beef fits safely into a Mediterranean diet without raising heart disease risk

AI analysis of biopsy slides predicts rectal cancer treatment response

New clinical trial shows promise for shorter TB treatment

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

New AI investment aims to accelerate the search for an effective HIV vaccine

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