Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Genetic factors influence obesity risk in children exposed to gestational diabetes

Children exposed to gestational diabetes in utero with a specific variation of a common gene are at a higher risk of becoming overweight or obese during childhood, according to a new study by researchers at the University of Colorado Anschutz Medical Campus.

30 May 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

Midlife weight loss may lower your long-term risk of diabetes, study finds

This study shows that midlife weight loss, without medical interventions, reduces chronic disease risk and supports longevity, beyond diabetes benefits.

29 May 2025

Cancer drug combo extends the lifespan of mice by 30%

The combination of two cancer drugs, rapamycin and trametinib, can extend the lifespan of mice by 30%, according to a study led by researchers at UCL and the Max Planck Institute for Biology of Ageing, Germany.

28 May 2025

High fat diet disrupts metabolism and increases disease risk

Consuming a high-fat diet can lead to a variety of health problems - not only weight gain but also an increased risk of diabetes and other chronic diseases.

28 May 2025

Combination of trametinib and rapamycin extends lifespan in mice

The researchers were able to show that Trametinib alone extends the lifespan of mice by 5-10%, while Rapamycin alone increases lifespan by 15-20%. Together, the drugs have a combinatorial effect that extends the life of the mice by around 30%.

28 May 2025

Scientists discover unique molecular fingerprints of insulin resistance

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

27 May 2025

New vascularized model of stem cell islets promises to improve diabetes research

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

23 May 2025

Cutting back on sugary drinks may protect men’s fertility, review finds

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, potentially impairing male reproductive health. This narrative review highlights dose-response effects, mechanisms, and research gaps, calling for further studies on diverse populations.

22 May 2025

Endurance training leads to significant drops in vascular resistance and diastolic blood pressure

Eight months of supervised marathon training in Finnish adults led to moderate reductions in peripheral diastolic blood pressure, systemic vascular resistance, and extracellular water volume. Central (aortic) blood pressure showed a non-significant decline, highlighting the specific impact of exercise on vascular health.

22 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

22 May 2025

BMI changes in adolescence mediate the effect of air pollution on metabolic health

Changes in Body Mass Index (BMI) during adolescence play an important role in the association between air pollution exposure and insulin resistance, according to a new study led by investigators from the Keck School of Medicine of USC.

20 May 2025

Eating kombu daily enhances gut health and heart markers in men

A 12-week randomized trial found that daily intake of boiled kombu (Laminaria japonica) powder reduced body fat and raised adiponectin in Japanese men, while improving blood pressure and gut microbiota in both sexes. No significant effects were seen in women for body fat reduction or adiponectin.

20 May 2025

Study shows any exercise can benefit older adults' health

Physical activity helps protect older adults against disease. A new study reveals that the health benefits also apply to those who exercise less than the recommended amount.

20 May 2025

Diabetes drug shows potential in slowing prostate cancer progression

A drug used to treat type 2 diabetes may also be effective in slowing the progression of prostate cancer.

20 May 2025

Targeting brain neurons to successfully treat type 2 diabetes

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.

15 May 2025

TMEM219 inhibition shows promise in restoring intestinal health in IBD

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases.

15 May 2025

Snus withdrawal linked to weight gain and elevated blood pressure

Snus users who stopped using snus experienced higher blood pressure and gained weight. This has been shown by a research group at Linköping University, Sweden, in a study on 33 people, published in Harm Reduction Journal.

15 May 2025