Renal disease News and Research

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Gore announces first implantation in IDE clinical study of ACUSEAL Vascular Graft in hemodialysis patients

W. L. Gore & Associates reported that the first patient, in an Investigational Device Exemption (IDE) clinical study evaluating the self sealing GORE® ACUSEAL Vascular Graft in patients on hemodialysis, has been surgically implanted with the device. The successful surgical procedure was performed on July 29, 2010 at Greenville Hospital System in Greenville, South Carolina. Less than 24 hours after the device was implanted it was successfully cannulated or punctured for initial hemodialysis access.

13 Aug 2010

Tengion announces clinical, corporate and second-quarter financial updates

Tengion Inc. today provided a corporate and product development update and reported its financial results for the quarter ended June 30, 2010.

12 Aug 2010

AACN endorses new clinical practice guidelines developed by Renal Physicians Association

The American Association of Critical-Care Nurses (AACN) recently endorsed the clinical practice guideline, "Shared Decision Making in the Appropriate Initiation of and Withdrawal from Dialysis," developed by Renal Physicians Association (RPA), Rockville, Md.

11 Aug 2010

Hemodialysis with AVF depends on patient’s health insurance: Study

Kidney disease patients insured by some federally sponsored national health care organizations are more likely to undergo an important predialysis procedure than patients with other types of insurance, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results may provide insights into ways to improve kidney-related care for patients before they go on dialysis.

10 Aug 2010

Pay-for-performance makes its way into dialysis clinics

Chattanooga (Tenn.) Times Free Press: A new Medicare rule may ding dialysis centers by up to two percent of their reimbursement in 2012 if they don't meet quality standards the agency sets. The program "is the agency's first pay-per-performance system, and it won't be the last." The agency has, however, run various experiments that pay providers for better performance.

10 Aug 2010

Research shows variations in care that kidney disease patients receive before starting dialysis

The wealth or poverty of kidney disease patients' communities impacts the quality of care patients receive before starting dialysis, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results suggest that medical professionals need to improve care for patients who have not yet started dialysis.

6 Aug 2010

Tips for caregivers to better manage their loved one's health care

According to the National Alliance for Caregiving, more than 65 million people in the United States serve as informal caregivers, typically for family members. This equates to more than one out of every four people serving as unpaid caregivers.

2 Aug 2010

Study reveals high rate of atrial fibrillation in patients with early stages of CKD

Millions of Americans in the early stages of chronic kidney disease (CKD) are at an increased risk of having atrial fibrillation (AF) - a major risk factor for stroke - according to new research by investigators at Wake Forest University Baptist Medical Center.

29 Jul 2010

Genzyme accepts CMS decision for delaying Renvela administration to dialysis patients

Genzyme Corp.today said it welcomed the Centers for Medicare and Medicaid Services' decision not to include oral medications without IV equivalents in Medicare's End Stage Renal Disease patient benefit. According to the final rule, these medications, including Genzyme's Renvela (sevelamer carbonate), will not be included in the bundle until January 1, 2014.

28 Jul 2010

Medicare to bundle payments for end-stage renal care, reward quality

Medicare payment for end-stage renal disease care may soon be tied to performance and quality measures if a new proposed rule issued by the Centers for Medicare and Medicaid Services is finalized. "If the rule is finalized, ESRD providers that do not meet set standards" - two measures for anemia management and one for hemodialysis quality - "could have their Medicare payments lowered by up to 2 percent starting January 2012, the CMS said" (McKinney, 7/26).

28 Jul 2010

New study reveals potential role of TGF-β1 in kidney disease

Fibrosis in the kidney is one of the key causes of progressive renal failure. High levels of the inflammatory molecule TGF-β1 in the kidney tubules due to tissue damage can cause fibrosis as well as nephron degeneration, resulting in loss of kidney function. To clarify the mechanisms regulating TGF-β1-mediated renal fibrosis, Koesters et al expressed high levels of TGF-β1 in renal tubules of mice. Nephron degeneration in this system was mediated by decomposition of the tubular cells. These data suggest that TGF-β1 may play a novel role in cell death of renal cells, thus contributing to renal fibrosis.

28 Jul 2010

Abbot's innovative solutions to be highlighted at AACC

A first-of-its-kind test that detects HIV infection earlier than ever before in the United States; a molecular assay for identification of two common sexually transmitted diseases; and an enhanced integrated analyzer offering significant workflow improvements; are among the many new advances Abbott will highlight at this year's American Association for Clinical Chemistry Lab Expo which starts today in Anaheim.

27 Jul 2010

African Americans at increased risk of kidney failure caused by hypertension

Regardless of demographics, African American patients with hypertensive nephrosclerosis have a higher rate of developing end stage renal disease than dying prematurely, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.Earlier studies showed patients of all races with Chronic Kidney Disease were at greater risk of dying prematurely from cardiovascular disease than reaching ESRD.

23 Jul 2010

BCBSGA offers key tips for caregivers for better health care management

According to the National Alliance for Caregiving, more than 65 million people in the United States serve as informal caregivers, typically for family members, which equates to more than one out of every four people serving as unpaid caregivers.

23 Jul 2010

KAI Pharmaceuticals completes enrollment in Phase 1 study of KAI-4169 for SHPT

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the Company has completed enrollment in a Phase 1 study of KAI-4169, a novel pharmaceutical agent for the treatment of secondary hyperparathyroidism, which is a frequent complication of end stage renal disease.

20 Jul 2010

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Kidney disease is a growing public health problem, with approximately half a million individuals in the United States requiring dialysis treatments to replace the function of their failed kidneys. The problem is particularly acute among African-Americans, whose rates of kidney disease are four times higher than those of European Americans.

20 Jul 2010

Proteinuria screening identifies risk for kidney disease progression

A morning urine test is superior to all other tests for detecting declining kidney performance in patients with diabetic kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that clinicians should monitor kidney function by measuring the albumin:creatinine ratio from a first morning urine sample.

16 Jul 2010

Study finds substantial regional variation in treatment practices for older adults with ESRD

There is substantial regional variation in treatment practices for care of older adults with end-stage renal disease, including receipt of hospice care and discontinuation of dialysis before death, according to a study in the July 14 issue of JAMA.

14 Jul 2010

UMMC to partner with Mayo Clinic to discover new therapies, train new medical scientists

The University of Mississippi Medical Center will partner with the renowned Mayo Clinic on a series of initiatives intended to convert laboratory discoveries into new therapies and train a new generation of medical scientists.

9 Jul 2010

Dysautonomia linked to CKD: Study

Individuals with a high resting heart rate and a low beat-to-beat heart rate variability have an increased risk of developing kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The findings suggest that the behavior of the autonomic nervous system may be a sentinel marker for late development of certain cases of kidney disease.

9 Jul 2010

Renal disease News and Research

Gore announces first implantation in IDE clinical study of ACUSEAL Vascular Graft in hemodialysis patients

Tengion announces clinical, corporate and second-quarter financial updates

AACN endorses new clinical practice guidelines developed by Renal Physicians Association

Hemodialysis with AVF depends on patient’s health insurance: Study

Pay-for-performance makes its way into dialysis clinics

Research shows variations in care that kidney disease patients receive before starting dialysis

Tips for caregivers to better manage their loved one's health care

Study reveals high rate of atrial fibrillation in patients with early stages of CKD

Genzyme accepts CMS decision for delaying Renvela administration to dialysis patients

Medicare to bundle payments for end-stage renal care, reward quality

New study reveals potential role of TGF-β1 in kidney disease

Abbot's innovative solutions to be highlighted at AACC

African Americans at increased risk of kidney failure caused by hypertension

BCBSGA offers key tips for caregivers for better health care management

KAI Pharmaceuticals completes enrollment in Phase 1 study of KAI-4169 for SHPT

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Proteinuria screening identifies risk for kidney disease progression

Study finds substantial regional variation in treatment practices for older adults with ESRD

UMMC to partner with Mayo Clinic to discover new therapies, train new medical scientists

Dysautonomia linked to CKD: Study

Free guide - Everything about renal proximal tubule cells eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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