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Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack.

17 Oct 2018

Study to explore bioethics of brain organoids

Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids.

16 Oct 2018

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

A study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that certain aggressive molecular features were far more prevalent in tumors from Nigerian women than in black or white American women.

16 Oct 2018

Age-related estrogen increase may be the culprit behind inguinal hernias in men

An age-related increase in estrogen may be the culprit behind inguinal hernias, a condition common among elderly men that often requires corrective surgery, according to a Northwestern Medicine study was published Oct. 15 in Proceedings of the National Academy of Sciences.

16 Oct 2018

Study uses novel approach to investigate genetic origins of mental illnesses

A study in Biological Psychiatry has established a new analytical method for investigating the complex genetic origins of mental illnesses using brain cells that are grown in a dish from human embryonic stem cells.

16 Oct 2018

Study uncovers important role of PRMT1 in dilated cardiomyopathy

In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy.

16 Oct 2018

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful.

15 Oct 2018

Researchers identify basic relationships of cell cycle and cellular senescence in the placenta

Working with researchers from Stanford University and St. Anna Children's Cancer Research, researchers from Jürgen Pollheimer's laboratory at the Medical University of Vienna's Department of Obstetrics and Gynecology have now, for the first time, identified basic relationships of the cell cycle and cellular senescence in the human placenta.

15 Oct 2018

New project aims to deliver fast, effective treatment for autoimmune rheumatic diseases

Affecting around 2 % of the population, autoimmune rheumatic diseases can have severe symptoms, including painful and swollen joints, fever, rashes, fatigue and sensitivity to the sun, with patients needing regular check-ups.

15 Oct 2018

Researchers to study the use of CRISPR on human liver on-a-chip platform

Two Arizona State University professors are among the first recipients of Somatic Cell Genome Editing grants from the National Institutes of Health Common Fund. The $2,600,000, five-year grant will fund the first study of the genome editing technology CRISPR to be used on a "human liver on-a-chip" platform.

15 Oct 2018

Scientists use haploid stem cells to produce mice with same-sex parents

In a new study, Chinese researchers were able to produce healthy mouse pups with two mothers. The research involved the use of haploid embryonic stem cells.

12 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Working Towards a Sustainable Future for the NHS

An interview with Jennifer Lee, Director of Market Access and Advocacy at Janssen UK, the pharmaceutical company of Johnson & Johnson, discussing the importance of innovation in the private sector and making new technologies available to the NHS.

12 Oct 2018

Study suggests new approach to treat life-threatening blood disorder in children

Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease.

12 Oct 2018

Legal scholars sound alarm on academies' report about returning research results to participants

In a Policy Forum article appearing in the Oct. 12 issue of Science, leading bioethics and legal scholars sound the alarm about a recent report from National Academies of Science, Engineering, and Medicine.

12 Oct 2018

Scientists discover molecular link between body weight and early-onset puberty

Becoming overweight at a young age can trigger a molecular chain reaction that leads some girls to experience puberty early, according to new research published in Nature Communications.

11 Oct 2018

Themis, Max-Planck-Innovation sign license agreement to develop and commercialize oncolytic virotherapies

Themis announced today that it has entered into a license agreement with Max-Planck-Innovation GmbH, the technology transfer agency of the Max Planck Society in Germany, granting it exclusive worldwide license to develop, manufacture and commercialize therapies based on an oncolytic measles virus platform that was jointly developed by the Eberhard-Karls-University Tübingen and the Max Planck Institute for Biochemistry. Financial terms of the agreement were not disclosed.

11 Oct 2018

Common gene variants linked to migraine risk in African-American children

Pediatric researchers have discovered common gene variants associated with migraines in African-American children.

11 Oct 2018

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Carnegie's Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combatting a host of diseases associated with altered levels of lipoproteins like LDL ("bad cholesterol").

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Genome News and Research

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

Study to explore bioethics of brain organoids

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

Age-related estrogen increase may be the culprit behind inguinal hernias in men

Study uses novel approach to investigate genetic origins of mental illnesses

Study uncovers important role of PRMT1 in dilated cardiomyopathy

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Researchers identify basic relationships of cell cycle and cellular senescence in the placenta

New project aims to deliver fast, effective treatment for autoimmune rheumatic diseases

Researchers to study the use of CRISPR on human liver on-a-chip platform

Scientists use haploid stem cells to produce mice with same-sex parents

Metabolome tests could be new way to measure obesity and health

Working Towards a Sustainable Future for the NHS

Study suggests new approach to treat life-threatening blood disorder in children

Legal scholars sound alarm on academies' report about returning research results to participants

Scientists discover molecular link between body weight and early-onset puberty

Themis, Max-Planck-Innovation sign license agreement to develop and commercialize oncolytic virotherapies

Common gene variants linked to migraine risk in African-American children

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Research team awarded $3.6 million to assess safety of genome editing

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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