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ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

ARIAD Pharmaceuticals, Inc. today announced that it is discontinuing the Phase 3 EPIC (Evaluation of Ponatinib versus Imatinib in Chronic Myeloid Leukemia) trial of Iclusig (ponatinib) in patients with newly diagnosed chronic myeloid leukemia.

18 Oct 2013

$Vertebral augmentation for spinal fractures improves patient survival, reduces overall costs$

Vertebral augmentation for spinal fractures improves patient survival, reduces overall costs

A study of 69,000 Medicare patient records led by Johns Hopkins researchers shows that people with spine compression fractures who undergo operations to strengthen back bones with cement survive longer and have shorter overall hospital stays than those who stick with bed rest, pain control and physical therapy.

18 Oct 2013

Use of effective, risky drug therapies by Medicare patients varies across US

A new report from the Dartmouth Atlas Project shows that the use of both effective and risky drug therapies by Medicare patients varies widely across U.S. regions, offering further evidence that location is a key determinant in the quality and cost of the medical care that patients receive.

18 Oct 2013

Good news: Knowing risk early, women can take action to prevent osteoporosis

On World Osteoporosis Day, October 20, the International Osteoporosis Foundation (IOF) is calling for women to take action now to protect their bone health. Broken bones due to osteoporosis often result in pain, immobility and loss of quality of life as well as early death.

17 Oct 2013

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation , today announced the results of the MPACT phase III clinical trial of ABRAXANE® in combination with gemcitabine were published online in the October 16th edition of the New England Journal of Medicine.

17 Oct 2013

ESTEVE reports positive top line results from E-58425 phase II trial for acute pain

ESTEVE, a pharmaceutical company focused on developing novel therapeutics for pain today announces positive top line results from its recently completed phase II trial, which was designed to evaluate the efficacy and safety of E-58425 in acute pain.

16 Oct 2013

Seven promising scientists named 2013 NYSCF - Robertson Investigators

The New York Stem Cell Foundation today named seven of the most promising scientists as its 2013 NYSCF - Robertson Investigators.

16 Oct 2013

UCSD professor receives $6.25M grant to support research on chronic lymphocytic leukemia

The Leukemia & Lymphoma Society has awarded Thomas J. Kipps, MD, PhD, Distinguished Professor of Medicine at the University of California, San Diego School of Medicine, with a 5-year, $6.25 million Specialized Center of Research program grant to support research on chronic lymphocytic leukemia (CLL), the most common adult leukemia in the United States.

16 Oct 2013

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

University of Cincinnati (UC) researchers have been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to study an isoform that plays a critical role in human resistance to fatigue.

16 Oct 2013

microRNAs may serve as therapeutic targets and predictors of metastasis

A class of molecules called microRNAs may offer cancer patients two ways to combat their disease.

15 Oct 2013

UC San Diego researcher awarded grant to advance research on chronic lymphocytic leukemia

The Leukemia & Lymphoma Society has awarded Thomas J. Kipps, MD, PhD, Distinguished Professor of Medicine at the University of California, San Diego School of Medicine, with a 5-year, $6.25 million Specialized Center of Research program grant to support research on chronic lymphocytic leukemia, the most common adult leukemia in the United States.

15 Oct 2013

FDA approves OTREXUP injection for adults with RA, children with active pJIA

Antares Pharma, Inc. today announced the approval of OTREXUP (methotrexate) injection by the U.S. Food and Drug Administration. OTREXUP is the first FDA approved subcutaneous methotrexate for once weekly self-administration with an easy-to-use, single dose, disposable auto injector.

14 Oct 2013

Researchers identify genetic variants associated with Barrett's and esophageal cancer

An international consortium co-led by researchers at Fred Hutchinson Cancer Research Center and the QIMR Berghofer Medical Research Institute in Australia has identified four genetic variants associated with an increased risk of esophageal cancer and its precursor, a condition called Barrett's esophagus.

14 Oct 2013

Resveratrol can make tumor cells more susceptible to radiation treatment

A recent study by a University of Missouri researcher shows that resveratrol, a compound found in grape skins and red wine, can make certain tumor cells more susceptible to radiation treatment. This research, which studied melanoma cells, follows a previous MU study that found similar results in the treatment of prostate cancer.

12 Oct 2013

Canadian discovery could lead to development of vaccine against Epstein-Barr virus

Development of a vaccine against Epstein-Barr virus has taken a step forward with the Canadian discovery of how EBV infection evades detection by the immune system.

12 Oct 2013

Vitamin D supplements ineffective in preventing osteoporosis, finds study

Taking vitamin D supplements does not improve bone mineral density at the total hip, spine, forearm, or in the body as a whole, a large meta-analysis involving more than 4000 healthy adults published in The Lancet has found.

11 Oct 2013

Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies. Now for the first time, scientists will combine NK cell therapy with an immunocytokine to target children with relapsed/refractory disease including those with bulky tumors.

11 Oct 2013

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

The National University of Singapore (NUS) and A*STAR will be jointly establishing the S$148 million Singapore Centre for Nutritional Sciences, Metabolic Diseases, and Human Development (SiNMeD).

11 Oct 2013

Crucial role of orthopedic surgeons in diagnosing mTBI among trauma care patients

In the United States, approximately 1.4 million people suffer a traumatic brain injury (TBI) each year. Of those injuries, three out of four are minor TBI (mTBI)-a head injury that causes a temporary change in mental status including confusion, an altered level of consciousness, or perceptual or behavioral impairments.

11 Oct 2013

Combining gene therapy with stem cells leads to faster healing of burns

Johns Hopkins researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound.

10 Oct 2013

Bone News and Research

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

Vertebral augmentation for spinal fractures improves patient survival, reduces overall costs

Use of effective, risky drug therapies by Medicare patients varies across US

Good news: Knowing risk early, women can take action to prevent osteoporosis

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

ESTEVE reports positive top line results from E-58425 phase II trial for acute pain

Seven promising scientists named 2013 NYSCF - Robertson Investigators

UCSD professor receives $6.25M grant to support research on chronic lymphocytic leukemia

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

microRNAs may serve as therapeutic targets and predictors of metastasis

UC San Diego researcher awarded grant to advance research on chronic lymphocytic leukemia

FDA approves OTREXUP injection for adults with RA, children with active pJIA

Researchers identify genetic variants associated with Barrett's and esophageal cancer

Resveratrol can make tumor cells more susceptible to radiation treatment

Canadian discovery could lead to development of vaccine against Epstein-Barr virus

Vitamin D supplements ineffective in preventing osteoporosis, finds study

Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

Crucial role of orthopedic surgeons in diagnosing mTBI among trauma care patients

Combining gene therapy with stem cells leads to faster healing of burns

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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