Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Breast Health Center receives three-year accreditation from NAPBC

The Breast Health Center at Women & Infants Hospital of Rhode Island recently earned a three-year accreditation from the National Accreditation Program for Breast Centers.

3 Mar 2011

Neuralstem announces initiation of NSI-189 Phase Ia trial for major depressive disorder

Neuralstem, Inc. announced that the first subject was dosed yesterday in a Phase Ia trial to evaluate the safety of its drug, NSI-189, which is being developed for the treatment of major depressive disorder and other psychiatric indications. NSI-189 is the lead compound in Neuralstem's neurogenerative small molecule drug platform. This phase of the trial is in healthy volunteers and seeks to determine the maximum tolerated single dose.

2 Mar 2011

Additional pathology tests can improve survival rates in patients with oesophageal cancer

A University of Adelaide medical researcher says current treatment for people diagnosed with oesophageal cancer could be improved with additional pathology tests.

2 Mar 2011

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

Syndax Pharmaceuticals, a clinical-stage epigenetics oncology company, announced the National Cancer Institute (NCI) will sponsor a multi-center phase 2 study of Syndax's lead product entinostat, a novel inhibitor of histone deacetylases (HDAC), and anastrozole, an aromatase inhibitor, in postmenopausal women with operable triple negative breast cancer to evaluate biomarkers and surrogates for response.

2 Mar 2011

U-M's SIVQ software-tool can pinpoint cell and tissue samples more accurately

Ulysses Balis, M.D., clicks a mouse to identify a helicopter in a satellite photo of Baghdad, Iraq. With another click, an algorithm that he and his team designed picks out three more choppers without highlighting any of the buildings, streets, trees or cars.

1 Mar 2011

Radiologists develop new non-surgical post-mortem technique

A new non-surgical post-mortem technique that has the potential to revolutionise the way autopsies are conducted around the world has been pioneered by forensic pathologists and radiologists at the University of Leicester in collaboration with the University Hospitals of Leicester NHS Trust.

1 Mar 2011

ADC announces RNAscope technology clinical study results for HPV-associated head and neck cancers

Advanced Cell Diagnostics, Inc. today announced the results of its clinical study utilizing RNAscope technology to detect human papillomavirus E6/E7 mRNA in routine clinical specimens of head and neck cancer.

From Advanced Cell Diagnostics 1 Mar 2011

Dermatan sulfate holds potential as an additional biomarker for Sanfilippo disease

Sanfilippo disease is a rare disorder caused by the failure of enzymes to break down specific kinds of complex carbohydrates, resulting in their accumulation in cells and often severe physical and neurological problems - and sometimes early death.

1 Mar 2011

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals for the development of an active vaccination programme against Alzheimer's disease.

1 Mar 2011

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose tissue with muscle cells from rat hearts.

1 Mar 2011

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals (GSK) for the development of an active vaccination programme against Alzheimer´s disease. While the lead vaccine candidate AD02 is currently in phase II clinical testing, two additional preclinical programmes have been completed successfully. The second programme was related to alternative vaccine candidates generated by AFFiRiS´ AFFITOME® technology, including candidate AD03. Based on the promising preliminary results of this programme, GSK exercised its option for the alternative vaccine candidates which triggered a EUR 2.5 million payment to AFFiRiS. An additional EUR 1 million payment became due simultaneously for the successful completion of tests of alternative vaccine formulations.

28 Feb 2011

EPA approves BioNeutral's Ygiene 206 antimicrobial disinfectant

BioNeutral Group, Inc., a specialty life science technology-based company, today announced that it has received approval and registration from the Environmental Protection Agency (EPA) in response to the Company's regulatory application for its Ygiene™ 206.

28 Feb 2011

Final data from 4SC vidofludimus ENTRANCE Phase IIa trial against IBD presented at ECCO IBD Conference

4SC AG, a drug discovery and development company focused on autoimmune and cancer indications, announces the final data from the ENTRANCE Phase IIa trial in inflammatory bowel disease with vidofludimus, an oral inhibitor of interleukin-17 release and DHODH, including the secondary endpoints comprising the analysis of CDAI and CAI disease scores, change of prednisolone intake and threshold doses, safety, pharmacokinetics and biomarkers.

28 Feb 2011

Study: HT may affect symptom load and quality of life unrelated to hypothyroidism

Hashimoto's thyroiditis, an inflammatory disorder of the thyroid, is the most common cause of hypothyroidism, but a study has suggested that even when thyroid function is normal, HT may increase symptoms and decrease quality of life, as described in an article in Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc.

27 Feb 2011

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

Roche announced that a study published online today in the American Journal of Clinical Pathology demonstrated the ability of the cobas HPV Test to individually detect HPV-16 and HPV-18, two of the highest risk HPV genotypes causing 70 percent of cervical cancer cases.

From Roche Sequencing and Life Science 25 Feb 2011

New rapid and inexpensive test can effectively identify never-smoking group with lung adenocarcinoma

An inexpensive and rapid testing method can effectively identify a sub-group of never-smoking lung cancer patients whose tumors express a molecule associated with increased risk of disease progression or recurrence, US researchers have found.

25 Feb 2011

Refrigerated whole blood may have shelf life beyond current standard of 24 to 48 hours

In a finding that may potentially improve survival from war injuries and disasters, laboratory researchers report that refrigerated whole blood may have a shelf life well beyond the current standard of 24 to 48 hours.

24 Feb 2011

Ibio acquires Orphan Drug Designation and Fabry disease therapeutic program from Kentucky

iBio, Inc. today announced it has acquired Orphan Drug Designation for plant-produced human alpha galactosidase A and related property rights from an affiliate of Kentucky Bioprocessing LLC and has initiated a program, based on its iBioLaunch platform, to develop an improved version of the enzyme for therapy of Fabry disease.

23 Feb 2011

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

For the fifth consecutive year, Women & Infants Hospital of Rhode Island has been named a Center of Excellence for Neonatal Care by the Clinical Sciences Institute of OptumHealth, an independent audit company. According to OptumHealth, not all health care providers are created equal. For complex medical conditions, the disparity is especially high.

23 Feb 2011

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

A group of researchers led by scientists from the Virginia Bioinformatics Institute at Virginia Tech have developed a new technology that detects distinct genetic changes differentiating cancer patients from healthy individuals and could serve as a future cancer predisposition test.

23 Feb 2011

Pathology News and Research

Further Reading

Breast Health Center receives three-year accreditation from NAPBC

Neuralstem announces initiation of NSI-189 Phase Ia trial for major depressive disorder

Additional pathology tests can improve survival rates in patients with oesophageal cancer

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

U-M's SIVQ software-tool can pinpoint cell and tissue samples more accurately

Radiologists develop new non-surgical post-mortem technique

ADC announces RNAscope technology clinical study results for HPV-associated head and neck cancers

Dermatan sulfate holds potential as an additional biomarker for Sanfilippo disease

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

EPA approves BioNeutral's Ygiene 206 antimicrobial disinfectant

Final data from 4SC vidofludimus ENTRANCE Phase IIa trial against IBD presented at ECCO IBD Conference

Study: HT may affect symptom load and quality of life unrelated to hypothyroidism

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

New rapid and inexpensive test can effectively identify never-smoking group with lung adenocarcinoma

Refrigerated whole blood may have shelf life beyond current standard of 24 to 48 hours

Ibio acquires Orphan Drug Designation and Fabry disease therapeutic program from Kentucky

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

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