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COVID-19 may provoke IgA-associated vasculitis

In a new study, scientists showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provokes immunoglobulin A (IgA)-associated vasculitis (IgAV).

30 Aug 2022

Disrupting a virus’s genome packaging can halt replication, study finds

Like savvy international travelers, viruses know exactly how to pack. With the genetic instructions for the next generation folded just so, snuggled into a custom-made outer covering studded with cell-grabbing proteins, these tiny invaders quest for new digs on the reg.

30 Aug 2022

The effects of amino acid substitutions on the affinity of the SARS-CoV-2 spike RBD to the human receptor hACE2

Researchers performed a structural bioinformatics analysis to evaluate the binding energy of the SARS-CoV-2 Omicron variants of concern spike protein receptor-binding domain to human angiotensin-converting enzyme 2 receptor compared to other VOCs.

30 Aug 2022

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

In this interview, we speak to Morteza Sarmadi from MIT about his labs latest research that developed microparticles able to deliver self-boosting vaccines.

30 Aug 2022

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

A study conducted by researchers in Brazil, Australia, Austria and the United States has made significant discoveries about a type of pediatric cancer with no approved drugs for treatment and with a low survival rate.

29 Aug 2022

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strategy to overcome tumor-induced immunosuppression.

29 Aug 2022

Review of ERAS programs in minimally invasive gynecologic surgery shows improved patient outcomes

Following Enhanced Recovery After Surgery (ERAS) protocols designed to minimize surgical stress results in improved patient recovery and satisfaction, reduced postoperative complications, and shorter hospital stays, according to a review of ERAS programs in minimally invasive gynecologic surgery by UT Southwestern researchers.

29 Aug 2022

Higher-cost Medicare Advantage plan not linked to better quality health care for seniors

Enrolling in a higher-cost Medicare Advantage plan may not always get seniors better quality health care, according to a new RAND Corporation study.

29 Aug 2022

Researchers discover new therapeutic target for triple-negative breast cancer

Breast cancer is categorized into three major subtypes: hormone receptor-positive, HER2-positive, and triple-negative.

29 Aug 2022

Anonymous $5.75 million gift will enable UVA to fight against rare blood cancers

A gift of more than $5.75 million from anonymous donors will allow UVA Cancer Center to speed the development of new treatments for rare blood cancers and provide more patients with these cancers access to cutting-edge clinical trials.

29 Aug 2022

Viruses modify host cellular machinery to produce high amounts of viral progeny

The study, published in Nature Communications, shows a new mechanism whereby viruses modify cellular machinery so that it can better read the instructions in the genome of the invading virus.

29 Aug 2022

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease.

29 Aug 2022

Older people experiencing homelessness more likely to die soon

A quarter of the participants in a long-term study of older people experiencing homelessness in Oakland died within a few years of being enrolled, UC San Francisco researchers found.

29 Aug 2022

Herpesvirus-6 and Epstein–Barr virus reactivation across acute SARS-CoV-2 patients

In a new story, scientists explored human herpesvirus-6 (HHV-6) and Epstein–Barr virus (EBV) reactivation among acute coronavirus disease 2019 (COVID-19) patients.

29 Aug 2022

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

The W.M. Keck Foundation has awarded a $1.2 million grant to medicinal chemistry and computational biology researchers at the University of Kansas and the University of Chicago focused on addressing a long-unresolved problem in biomedical research - finding molecules able to target the "undruggable proteome."

29 Aug 2022

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons.

29 Aug 2022

What are the clinical characteristics and complications of patients with a monkeypox infection?

Researchers described the clinical characteristics and complications of monkeypox virus infections.

29 Aug 2022

$SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction$

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

An analysis of more than 12,000 patients has found that the SGLT2 inhibitors dapagliflozin and empagliflozin reduce cardiovascular death or hospitalization for heart failure by 20% in heart failure patients with mildly reduced and preserved ejection fraction.

28 Aug 2022

Adding acetazolamide to intravenous loop diuretics decreases congestion in patients with acute decompensated heart failure

Acetazolamide added to intravenous loop diuretics decreases congestion within three days in patients with acute decompensated heart failure, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.

28 Aug 2022

Researchers develop a protein thermal shift chip for COVID-19

Announcing a new publication for Acta Materia Medica journal. Traditional protein chips are based on solid chips and cannot enable drug and target screening in a label-free manner.

26 Aug 2022

Drugs News and Research

COVID-19 may provoke IgA-associated vasculitis

Disrupting a virus’s genome packaging can halt replication, study finds

The effects of amino acid substitutions on the affinity of the SARS-CoV-2 spike RBD to the human receptor hACE2

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

Review of ERAS programs in minimally invasive gynecologic surgery shows improved patient outcomes

Higher-cost Medicare Advantage plan not linked to better quality health care for seniors

Researchers discover new therapeutic target for triple-negative breast cancer

Anonymous $5.75 million gift will enable UVA to fight against rare blood cancers

Viruses modify host cellular machinery to produce high amounts of viral progeny

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

Older people experiencing homelessness more likely to die soon

Herpesvirus-6 and Epstein–Barr virus reactivation across acute SARS-CoV-2 patients

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

What are the clinical characteristics and complications of patients with a monkeypox infection?

SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

Adding acetazolamide to intravenous loop diuretics decreases congestion in patients with acute decompensated heart failure

Researchers develop a protein thermal shift chip for COVID-19

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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