Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Paracetamol reduces damage caused to kidneys following severe muscle injury

The commonly-used painkiller Paracetamol can protect against kidney failure after severe muscle injury, according to research at the University of Essex.

4 Feb 2010

Patients with high levels of proteinuria have increased risk of all-cause death

Patients with high levels of proteinuria (protein in urine) in addition to another marker of reduced kidney function had an associated increased risk of all-cause death, heart attack or progression to kidney failure, according to a study in the February 3 issue of JAMA.

3 Feb 2010

One-third of doctors and diabetes patients prioritize health conditions differently

About one-third of doctors and their patients with diabetes do not see eye to eye on the most important health conditions to manage, according to a survey by the University of Michigan Medical School.

3 Feb 2010

Research offers new hope for rare metabolic disorder

A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has for the first time determined the mechanism of one of the cell's "recycling" enzymes, human alpha-galactosidase or alpha-GAL, as it breaks down substances in the lysosome, the cell's recycling center.

2 Feb 2010

Vantia Therapeutics initiates Phase IIb trial of VA106483 for nocturia

Vantia Therapeutics, an emerging pharmaceutical company developing novel, small molecule drugs targeting large, underserved medical markets, today announces it has begun its planned Phase IIb trial of its lead development compound VA106483 for nocturia.

2 Feb 2010

Minimally invasive living donor liver retrieval for pediatric transplant

NewYork-Presbyterian Morgan Stanley Children's Hospital is the only medical center in the United States to offer minimally invasive liver donation for pediatric transplantation. Surgeons use a laparoscopic technique to remove a section of liver from a living donor for implantation in a pediatric patient -- typically a parent donating to their child. The innovative approach promises dramatically improved recovery for the donor.

2 Feb 2010

Scientists find that protease HtrA2 can "clean" cells of oncogene WT1

Dr Jorg Hartkamp and Dr Stefan Roberts have found that the protease HtrA2 can "clean" cells of the oncogene WT1, which is found at high levels in many leukaemias and solid cancers such as breast and lung cancer.

From The University of Manchester 2 Feb 2010

Congressional leader stresses the importance of annual dilated eye exam for diabetes patients

In recognition of Black History Month, House Majority Whip James E. Clyburn is urging African Americans with diabetes to get an annual diabetic eye exam during February.

1 Feb 2010

DSG’s eCaseLink EDC system employed in clinical trials for treatment of chronic kidney disease

DSG’s eCaseLink™ Electronic Data Capture (EDC) and data management are currently being used by a biotechnology company for two current phase 2 and phase 2a clinical trials for treatments of progressive and chronic kidney disease.

1 Feb 2010

FMCNA ships dialysis machines and supplies for Haiti relief efforts

Fresenius Medical Care North America (FMCNA), the world's largest integrated provider of products and services for individuals undergoing dialysis because of chronic kidney failure, is donating and delivering dialysis supplies to Haitians, at a time when relief supplies continue to be slow to reach those in need following a devastating earthquake and aftershock.

30 Jan 2010

Medical equipment could be a key weapon in stopping nuclear waste seeping into environment

Medical equipment used for diagnosis of patients with heart disease and cancer could be a key weapon in stopping nuclear waste seeping into the environment, according to new research.

From The University of Manchester 30 Jan 2010

Econiche vaccine cited in February, 2010 issue of Scientific American

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today announced that Econiche(TM), the world's first vaccine developed to reduce the shedding by cattle of Escherichia coli (E. coli) O157, has been cited in the February, 2010 issue of Scientific American (Vol. 302, # 2).

29 Jan 2010

New research raises hopes that immune rejection of embryonic stem cell therapies can be avoided without drugs

New research in the FASEB Journal shows that bone marrow cells fuse to different types of cells, including embryonic stem cells, creating new hybrids that may evade immune rejection

29 Jan 2010

Level of key immune cells in kidney transplant patients may predict risk of skin cancer

Measuring certain types of immune cells may predict the high risk of skin cancer after kidney transplantation, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

29 Jan 2010

SCI indicates increased risk of declining kidney function in type 2 diabetics

In patients with type 2 diabetes, silent cerebral infarction (SCI)—small areas of brain damage caused by injury to small blood vessels—signals an increased risk of progressive kidney disease and kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

29 Jan 2010

Depression raises risks of advanced and severe complications from diabetes

Depression raises risks of advanced and severe complications from diabetes, according to a prospective study of Group Health primary-care patients in western Washington. These complications include kidney failure or blindness, the result of small vessel damage, as well as major vessel problems leading to heart attack or stroke.

28 Jan 2010

Research shows even mild to moderate kidney disease may diminish child's quality of life

Challenging prevailing wisdom that only children with end-stage kidney disease suffer physical, social, emotional and educational setbacks from their disease, research led by Johns Hopkins Children's Center shows that even mild to moderate kidney disease may seriously diminish a child's quality of life.

28 Jan 2010

Patients with NAFLD have higher overall mortality rate, say researchers

Researchers from the Karolinska Institute determined that patients with nonalcoholic fatty liver disease (NAFLD) have a higher overall mortality rate compared with the general population.

28 Jan 2010

TE can be accurately performed in majority of NAFLD patients to exclude advanced fibrosis

Researchers from France and Hong Kong determined that transient elastography (TE), a noninvasive, ultrasonic imaging modality, can be accurately performed in the majority of patients with nonalcoholic fatty liver disease (NAFLD) to exclude advanced fibrosis. Full findings of this study, funded by the Chinese University of Hong Kong, appear in the February issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

27 Jan 2010

Hypothermic machine perfusion outperforms standard cold-storage liver preservation

Preserving organs on ice prior to transplantation, an approach known as cold storage or CS, has been the standard practice in liver transplant for 20 years. Now there is new evidence that a technique called hypothermic machine perfusion (HMP) may offer an improvement, according to the first-ever study comparing the impact of the two techniques on transplant outcomes.

27 Jan 2010

Nephrology News and Research

Further Reading

Paracetamol reduces damage caused to kidneys following severe muscle injury

Patients with high levels of proteinuria have increased risk of all-cause death

One-third of doctors and diabetes patients prioritize health conditions differently

Research offers new hope for rare metabolic disorder

Vantia Therapeutics initiates Phase IIb trial of VA106483 for nocturia

Minimally invasive living donor liver retrieval for pediatric transplant

Scientists find that protease HtrA2 can "clean" cells of oncogene WT1

Congressional leader stresses the importance of annual dilated eye exam for diabetes patients

DSG’s eCaseLink EDC system employed in clinical trials for treatment of chronic kidney disease

FMCNA ships dialysis machines and supplies for Haiti relief efforts

Medical equipment could be a key weapon in stopping nuclear waste seeping into environment

Econiche vaccine cited in February, 2010 issue of Scientific American

New research raises hopes that immune rejection of embryonic stem cell therapies can be avoided without drugs

Level of key immune cells in kidney transplant patients may predict risk of skin cancer

SCI indicates increased risk of declining kidney function in type 2 diabetics

Depression raises risks of advanced and severe complications from diabetes

Research shows even mild to moderate kidney disease may diminish child's quality of life

Patients with NAFLD have higher overall mortality rate, say researchers

TE can be accurately performed in majority of NAFLD patients to exclude advanced fibrosis

Hypothermic machine perfusion outperforms standard cold-storage liver preservation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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