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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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From DeNovix Inc. 13 Mar 2020

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

A study led by researchers at Baylor College of Medicine reports that a hyperactive variant of enzyme ACOX1 produces elevated levels of toxic reactive oxygen species (ROS) and causes a previously unidentified late-onset neurodegenerative disorder.

12 Mar 2020

New nano strategy for 'trapping and zapping' antibiotic resistant genes

It's not enough to take antibiotic-resistant bacteria out of wastewater to eliminate the risks they pose to society. The bits they leave behind have to be destroyed as well.

12 Mar 2020

Study shows how the body's inflammatory response can counterproductively suppress regeneration

In a new peer-reviewed publication, University of Illinois at Chicago researchers describe how the body's response to inflammation, which helps to fight many kinds of infections, also can counterproductively suppress much-needed cell repair and regeneration in blood vessels.

12 Mar 2020

People want more money, control in exchange for genomic data

Genomic data donated by the public is valuable for the companies that collect it. But a recent survey finds that once people are aware of issues surrounding the use and security of genetic information, people are more concerned about how it might be used and expect to be better compensated for providing it.

11 Mar 2020

Blood test for microbial DNA could warn of cancer

A new study published in the journal Nature on March 11, 2020, could transform the currently held views on cancer causation and diagnosis. The researchers have come up with a new technique to detect the presence and type of cancer by looking at microbial DNA circulating in the blood of the person being screened.

11 Mar 2020

BIN1 deficit leads to impaired spatial learning and memory

Bridging integrator 1, known as BIN1, is the second most common risk factor for late-onset Alzheimer's disease, according to genome-wide studies of genetic variants. Yet, scientists know little about what this protein does in the brain.

11 Mar 2020

Microbial DNA in the blood could help identify who has cancer

When Gregory Poore was a freshman in college, his otherwise healthy grandmother was shocked to learn that she had late-stage pancreatic cancer. The condition was diagnosed in late December. She died in January.

11 Mar 2020

Canine study discovers novel genes associated with hip dysplasia and osteoarthritis

Hip dysplasia, common in both dogs and humans, and associated osteoarthritis are complex disorders influenced by a multitude of genes.

11 Mar 2020

Scientists receive €2.45 million funding for leukemia research

Leukemia stem cells are considered to be the starting point of leukemia; their elimination is a basic prerequisite for a successful long-term therapy. Scientists at Heidelberg University Hospital, the Heidelberg Institute for Stem Cell Technology and Experimental Medicine at the German Cancer Research Center, the German Cancer Research Center and the European Molecular Biology Laboratory have now obtained research funding of €2.45 million from the German Federal Ministry of Education and Research as part of the junior research alliance LeukoSyStem.

11 Mar 2020

New technology could enable more accessible form of electron cryo-microscopy

The Rosalind Franklin Institute has committed to developing a multi-million pound technology which enables a more accessible form of electron cryo-microscopy.

11 Mar 2020

Exploiting careless cancer cells to develop new drugs

Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? Researchers at Uppsala University have succeeded in developing a substance that has demonstrated promising results in experiments on both animal models and human cancer cells.

11 Mar 2020

Exploring the biological link between reactivated HSV and neurological disease

Without even knowing it, most of us carry around latent Herpes Simplex Virus in our nervous system- a simple result of being born and living together with others carrying the virus.

10 Mar 2020

CRISPR-Cas system can be used to effectively target colitis pathogen

Research at North Carolina State University shows that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the pathogen that causes colitis - a chronic, degenerative disease of the colon.

10 Mar 2020

How a virus forms a protective shell to evade the immune system

A virus is a small infectious agent that replicates only inside the living cells of an organism. Viruses can infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea.

10 Mar 2020

Inherited ventricular arrhythmia fairly common among Finnish Leonbergers

A new study in Finland has revealed that inherited malignant ventricular arrhythmia is fairly common among Finnish Leonbergers under three years of age. At its worst, such arrhythmia can result in the dog's sudden death.

10 Mar 2020

Study reports second ever case of a patient to be cured of HIV

A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI.

10 Mar 2020

Scientists create new tool to study the genetic underpinnings of brain disorders

Scientists at the UNC School of Medicine and colleagues created a new computational tool called H-MAGMA to study the genetic underpinnings of nine brain disorders, including the identification of new genes associated with each disorder.

9 Mar 2020

'Primitive' stem cells shown to replace and repair damaged blood vessels in the retina

Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes.

9 Mar 2020

New toolkit to repair DNA breaks linked to aging, cancer and MND discovered

A new 'toolkit' to repair damaged DNA that can lead to aging, cancer and Motor Neurone Disease has been discovered by scientists at the Universities of Sheffield and Oxford.

9 Mar 2020