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OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Sometimes vaccines need a little help to protect people against infectious diseases.

31 Oct 2019

Mutated version of DNA repair protein may illuminate its role in preventing cancer

Two trillion times each day, the cells in a typical human divide to replace old, damaged or dead cells. Before a cell divides, though, it makes an exact copy of its DNA, which will be passed on to the new cells.

31 Oct 2019

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common - and often treatment-resistant - form of kidney cancer, researchers at Johns Hopkins' departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them.

From Johns Hopkins Medicine 31 Oct 2019

KHN’s ‘What the Health?’: Spooky stuff

Open enrollment starts Nov. 1 in most states for people who buy health insurance under the Affordable Care Act. For the second year in a row, premiums for these individual market plans are down slightly, even without the federal tax penalty for those who remain uncovered.

31 Oct 2019

Mechanisms preserving cell identity are based on status of proteins housing DNA

The inheritance, not only of DNA, but of changes to proteins that package it, maintains the identity of cells as they multiply, a new study finds.

31 Oct 2019

Scientists identify protein that pulls the brake on nerve growth

During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists from the German Center for Neurodegenerative Diseases in Bonn have now identified a protein that regulates the growth of these extensions by pulling a brake.

31 Oct 2019

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

31 Oct 2019

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Calcium ions are essential to how muscles work effectively, playing a starring role in how and when muscles contract, tap energy stores to keep working and self-repair damage.

31 Oct 2019

Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

High-intensity workouts improve memory in older adults

Researchers at McMaster University who examine the impact of exercise on the brain have found that high-intensity workouts improve memory in older adults.

31 Oct 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Screening tool in pediatric ER accurately estimates suicide risk among youth

A suicide risk screening tool that Johns Hopkins Medicine implemented in its pediatric emergency department six years ago appears to provide an accurate gauge of which youth are most vulnerable and has identified more than 2,000 patients who might benefit from mental health treatment and resources, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins Medicine.

31 Oct 2019

Japanese chemists develop vicinal reaction for creating highly functionalized ketones

Organic chemists are molecular architects, designing sophisticated structures. As the molecules used in science and medicine become ever more complex, new tools are needed to piece together the building blocks.

31 Oct 2019

REANIMA project may overturn paradigms that underlie regenerative cardiology research

Research into new endogenous mechanisms of tissue regeneration is an innovative research avenue in cardiac regeneration.

31 Oct 2019

Olympus SLIDEVIEW™ VS200 Solution with Reliable, Flexible, and High-Throughput Slide Scanning

Using Olympus’ leading-edge X Line™ objectives enables higher resolution, flatter images for outstanding digital slides for quantitative data analysis.

From Evident Corporation - Life Sciences 31 Oct 2019

Discovery of 'cellular bike couriers' could shed light on disease spreading mechanisms

A previously unknown component of our cells that delivers proteins like a bike courier in heavy traffic could shed light on the mechanisms that allow cells to spread in diseases such as cancer.

31 Oct 2019

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Granulocyte colony-stimulating factor, which causes division and differentiation of bone marrow cells depending on the body's need for leukocytes, has a significant regulatory effect not only on innate, but also on adaptive immunity.

31 Oct 2019

Common early sign of cardiovascular disease associated with cancer risk

A Mayo Clinic-led study involving 488 cardiac patients whose cases were followed for up to 12 years finds that microvascular endothelial dysfunction, a common early sign of cardiovascular disease, is associated with a greater than twofold risk of cancer.

31 Oct 2019

Study finds altered brain asymmetry in autism spectrum disorder

The left and right halves of our brains develop differently, as each hemisphere 'specialises' in certain functions. For example, for most people the left hemisphere--controlling the right hand--is dominant for language.

31 Oct 2019

Research News and Research

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Mutated version of DNA repair protein may illuminate its role in preventing cancer

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

KHN’s ‘What the Health?’: Spooky stuff

Mechanisms preserving cell identity are based on status of proteins housing DNA

Scientists identify protein that pulls the brake on nerve growth

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Researchers discover key mechanism in insulin release by cholesterol metabolite

Discovery has potential to put the brakes on Parkinson's 'runaway train'

High-intensity workouts improve memory in older adults

Study identifies a kinase as potential target to treat heart failure

Screening tool in pediatric ER accurately estimates suicide risk among youth

Japanese chemists develop vicinal reaction for creating highly functionalized ketones

REANIMA project may overturn paradigms that underlie regenerative cardiology research

Olympus SLIDEVIEW™ VS200 Solution with Reliable, Flexible, and High-Throughput Slide Scanning

Discovery of 'cellular bike couriers' could shed light on disease spreading mechanisms

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Common early sign of cardiovascular disease associated with cancer risk

Study finds altered brain asymmetry in autism spectrum disorder

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