Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025

One shot to lower cholesterol for life? Scientists unlock a groundbreaking gene therapy

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction without altering DNA, offering a potential one-time treatment for high cholesterol.

11 Feb 2025

Changes to intermediate filament protein drive aggressive breast cancer growth

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

11 Feb 2025

AI approach reveals possible fusion of rare diseases in COVID-19 origins

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients.

10 Feb 2025

Study uncovers potential target for treating keloid scars

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress.

10 Feb 2025

Study examines how diet impacts gene expression in fat tissue

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

8 Feb 2025

Immune gene expression changes in myocardial infarction revealed through bioinformatics

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets.

8 Feb 2025

Understanding the role of alternative splicing in cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants.

8 Feb 2025

Study reveals how neurons save energy during protein synthesis

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks.

7 Feb 2025

Distinct myeloid-derived suppressor cell populations fuel aggressive brain tumor growth

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine.

7 Feb 2025

Pancreatic cancer immune landscape reveals opportunities for personalized therapies

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies.

7 Feb 2025

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer's disease

In a groundbreaking theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer's disease.

6 Feb 2025

New technology unlocks secrets of bacterial gene expression

How do bacteria - harmless ones living in our bodies, or those that cause disease - organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, captured which genes bacteria turn on in different situations and in different spatial environments.

6 Feb 2025

How olive oil bioactives regulate genes linked to insulin resistance

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity, inflammation, and beta-cell function, offering potential benefits for Type 2 Diabetes Mellitus prevention and management.

5 Feb 2025

Researchers discover how RNA molecules influence multiple generations

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies.

4 Feb 2025

Researchers develop model to identify tumor-fighting immune cells in lung cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

3 Feb 2025