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New dual-purpose contrast agent revolutionizes PET and MRI integration for enhanced diagnosis

A research team from IOCB Prague, working in collaboration with the University of Tübingen, Germany, and the Faculty of Science, Charles University, has developed a new type of contrast agent that can be used in both magnetic resonance imaging (MRI) and positron emission tomography (PET).

5 Aug 2024

Study provides novel insights into the molecular mechanisms of melanoma progression

Cong Peng et al., at Department of Dermatology, Xiangya Hospital, Central South University, China, conducted a study titled "NETO2 promotes melanoma progression via activation of the Ca²⁺/CaMKII signaling pathway" that investigates the role of Neuropilin and tolloid-like 2 (NETO2) in melanoma, a deadly form of skin cancer.

2 Aug 2024

New study links obesity to bacterium Megamonas

A recent study published in Cell Host & Microbe identifies a potential obesity-linked bacterium, Megamonas, from a large-scale cohort of obese individuals in China.

2 Aug 2024

New nanosensing technique enhances quality control for gene therapy vectors

Over the past few decades, there has been remarkable progress in genetic manipulation technologies, bringing us closer to the point where genes can be modified in vivo.

1 Aug 2024

Continuous noninvasive blood pressure monitoring using resonance sonomanometry

Resonance sonomanometry (RSM) for noninvasive, calibration-free continuous blood pressure (BP) measurement using ultrasound imaging.

1 Aug 2024

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Researchers at Xiamen University have made a significant advancement in cancer treatment by developing a novel class of X-ray-sensitizers (XSs) that could revolutionize radiotherapy.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

Sapio Sciences and Zifo Announce Strategic Partnership

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From Sapio Sciences 30 Jul 2024

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

29 Jul 2024

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Researchers find that the deletion of Gα13 in B-cells increases lymphoma risk by enhancing proliferation in gut-associated lymph nodes. Dietary glutamine significantly promotes these effects, highlighting a crucial link between diet and cancer.

29 Jul 2024

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

A research team led by UC San Diego has, for the first time, shown that a wearable, non-invasive device can measure activity in human cervical nerves in clinical settings.

29 Jul 2024

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

Researchers highlight the unprecedented success of GLP-1-based multi-receptor drugs in achieving substantial weight loss and improved health outcomes, potentially replacing bariatric surgery for obesity treatment.

28 Jul 2024

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Researchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins.

28 Jul 2024

Cordyceps sinensis shown to alleviate idiopathic pulmonary fibrosis in mice

A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough in acute myeloid leukemia treatment targets stem cells

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment.

24 Jul 2024

Study unveils key mechanisms behind colorectal cancer metastasis to the liver

In cases where cancer is fatal, nine out of ten times the culprit is metastasis.

24 Jul 2024

Creating the first genetically susceptible mice for late-onset Alzheimer's

Mice don't get Alzheimer's - and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.

24 Jul 2024

Oral-gut axis: How mouth bacteria impact your overall health

A recent review in Nature Reviews Microbiology highlights how oral and gut microbiomes interact, impacting overall human health. Oral microorganisms can enter the gut, contributing to dysbiosis and various diseases, necessitating further research on these complex interactions.

24 Jul 2024

in vivo News and Research

New dual-purpose contrast agent revolutionizes PET and MRI integration for enhanced diagnosis

Study provides novel insights into the molecular mechanisms of melanoma progression

New study links obesity to bacterium Megamonas

New nanosensing technique enhances quality control for gene therapy vectors

Continuous noninvasive blood pressure monitoring using resonance sonomanometry

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

Sapio Sciences and Zifo Announce Strategic Partnership

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Cordyceps sinensis shown to alleviate idiopathic pulmonary fibrosis in mice

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Breakthrough in acute myeloid leukemia treatment targets stem cells

Study unveils key mechanisms behind colorectal cancer metastasis to the liver

Creating the first genetically susceptible mice for late-onset Alzheimer's

Oral-gut axis: How mouth bacteria impact your overall health

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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