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IU researchers observe bacteria's 'DNA uptake' process

Indiana University scientists have made the first direct observation of a key step in the process that bacteria use to rapidly evolve new traits, including antibiotic resistance.

12 Jun 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

Scientists find novel tactic with potential for fighting medulloblastoma

Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in children. The results are scheduled for publication in Cancer Cell.

12 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Researchers isolate bacteria that pose triple threat from a patient in the U.S.

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States.

11 Jun 2018

Researchers identify oldest bubonic plague genome

An international team of researchers led by the Max Planck Institute for the Science of Human History has analyzed two 3,800-year-old Y. pestis genomes that suggest a Bronze Age origin for bubonic plague.

8 Jun 2018

International research team develops simplified CRISPR

Details of an advanced form of CRISPR technology have been published in Nature Communications.

8 Jun 2018

New research provides clues into development of mammalian cerebral cortex

The cerebral cortex - the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness - has fascinated neuroscientists for centuries.

8 Jun 2018

NCI cancer centers come together to discuss ways to eliminate HPV Cancers

The University of New Mexico Comprehensive Cancer Center has joined the other 69 cancer centers designated by the National Cancer Institute to issue a statement urging increased vaccination for human papillomavirus.

7 Jun 2018

Microbiotica collaborates with Genentech to develop drugs for IBD

Microbiotica, a leading player in microbiome-based therapeutics spun out of the Wellcome Sanger Institute, today announced that it has entered into a multi-year strategic collaboration with Genentech, a member of the Roche Group, to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease.

6 Jun 2018

Study finds how colon cancer alters its genes to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

6 Jun 2018

Researchers develop novel tool to analyze millions of single cells simultaneously

New research led by Holger Heyn at the Centro Nacional de Análisis Genómico of the Centre for Genomic Regulation, presents a sophisticated computational framework to analyze single-cell gene expression levels, scalable to process millions of individual cells.

From 10x Genomics, Inc. 6 Jun 2018

Finnish research solves family blood mystery

It's the late 1970s, and a man with an unexplained high hemoglobin level (Hb) is referred to Namsos Hospital north of Trondheim, Norway. It turns out that four members of his family have the same condition. Doctor Kjell Kanelønning is the physician who treats the family.

6 Jun 2018

Study identifies four tumor survival strategies in childhood cancer

Researchers have identified four main trajectories for the development of childhood cancer, two of which have been linked to disease relapse.

5 Jun 2018

New findings shed light on biological mechanisms of gene regulation

A team led by Prof. Stein Aerts uncovers how access to relevant DNA regions is orchestrated in epithelial cells.

5 Jun 2018

Study shows four survival strategies of tumor cells in childhood cancer

Cancer cells in children tend to develop by following four main trajectories - and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows.

5 Jun 2018

Researchers identify racial differences in breast cancer immune microenvironment

Roswell Park Comprehensive Cancer Center researchers have identified significant differences in the immune microenvironment of breast cancer tumors between African-American and white women, shedding light on the ways in which race can influence cancer development and outcomes.

4 Jun 2018

Free-floating DNA analysis test may help detect early-stage lung cancer

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas study suggests.

4 Jun 2018