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Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Scientists sequence and analyze genomes of Candida albicans

Candida albicans is one of the most formidable fungal species, causing infection in humans. Investigating the structure and reproduction methods of pathogenic populations can help us to understand how they emerge and spread.

10 Jul 2018

New study reveals transmission of NDM-bacteria between dogs and humans

In 2015, a New Delhi -metallo-beta-lactamase Escherichia coli bacteria was discovered in two Finnish dogs.An article recently published in the journal Eurosurveillance reveals that the dogs' owner did also carry the bacterium.

9 Jul 2018

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Study finds key evidence about genetic make-up of heart condition linked to sudden arrhythmic death

A new study published in Circulation, a peer-reviewed journal of the American Heart Association and led by a cardiologist at the Peter Munk Cardiac Centre at Toronto General Hospital has found evidence that only one of the 21 genes normally associated with Brugada Syndrome, a serious genetic heart condition associated with the risk of sudden arrhythmic death, is a definitive cause of the condition.

9 Jul 2018

Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Researchers discover critical link in mapping recurrent mutations of melanoma

A critical link in mapping recurrent mutations of melanoma -- the most serious form of skin cancer in humans -- has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University.

6 Jul 2018

Researchers find new way to convert skin cells into pluripotent stem cells

Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted to cells typical of early embryos, so-called induced pluripotent stem cells.

6 Jul 2018

The Bioethics of AI in the Healthcare Industry

With the advent of artificial intelligence, it is imperative that we examine the ethics of machine learning and data collection. Hugh Whittall, Director of the Nuffield Council on Bioethics, explains what AI is, how it is transforming the healthcare industry and the ethical concerns of the Council.

6 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

Mayo researchers determine how DNA repair protein gets to the site of damage

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets to the site of DNA damage. The authors say they hope this discovery research will help identify new therapies for ovarian cancer.

3 Jul 2018

NIH offers grant to examine potential of stem cell-derived cardiac cells for heart disease treatment

Examining the treatment potential of cardiac cells derived from human pluripotent stem cells may lead to dramatically altering the care of cardiac disease and heart injuries, thanks to a grant from the National Institutes of Health.

3 Jul 2018

Researchers develop new methods for studying evolution of cancer treatment resistance

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.

3 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Researchers discover gene that plays role in regulating body's immune response to infection

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

2 Jul 2018

Individuals may react differently to environmental chemicals based upon genetic profile

Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical.

30 Jun 2018

Genome News and Research

Researchers use genome editing to reduce cholesterol levels in animal model

Scientists sequence and analyze genomes of Candida albicans

New study reveals transmission of NDM-bacteria between dogs and humans

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Study finds key evidence about genetic make-up of heart condition linked to sudden arrhythmic death

Widespread transfer of genes between species appears to be key driver of evolution

Researchers discover critical link in mapping recurrent mutations of melanoma

Researchers find new way to convert skin cells into pluripotent stem cells

The Bioethics of AI in the Healthcare Industry

Researchers develop switch that can control genome editing

Mayo researchers determine how DNA repair protein gets to the site of damage

NIH offers grant to examine potential of stem cell-derived cardiac cells for heart disease treatment

Researchers develop new methods for studying evolution of cancer treatment resistance

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Researchers discover gene that plays role in regulating body's immune response to infection

Individuals may react differently to environmental chemicals based upon genetic profile

Enzyme TLK2 could serve as potential therapies for breast cancer, brain condition

Study finds sex-based differences in genetic risk factors for developing gliomas

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Genes associated with autism interact to modulate variable symptoms of disease

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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